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Platelet serotonin concentration and monoamine oxidase activity in unmedicated chronic schizophrenic and in schizoaffective patients

Published online by Cambridge University Press:  09 July 2009

Michael H. Joseph ,
Frank Owen ,
Harry F. Baker  and
Rachel C. Bourne
Michael H. Joseph*
Affiliation:
Division of Psychiatry, Clinical Research Centre, Harrow
Frank Owen
Affiliation:
Division of Psychiatry, Clinical Research Centre, Harrow
Harry F. Baker
Affiliation:
Division of Psychiatry, Clinical Research Centre, Harrow
Rachel C. Bourne
Affiliation:
Division of Psychiatry, Clinical Research Centre, Harrow
*
1Address for correspondence: Dr M. H. Joseph, Division of Psychiatry, Clinical Research Centre, Watford Road, Harrow, Middx. HAI 3UJ.
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Synopsis

Elevated blood serotonin, perhaps secondary to reduced platelet MAO, has been reported in a group of chronic schizophrenic patients. We have failed to find elevated platelet serotonin, or any relationship between platelet serotonin and MAO either in a group of unmedicated chronic schizophrenic patients or in a group of schizoaffective patients. Possible reasons for these discrepancies are discussed.

Type
Preliminary Communication
Information
Psychological Medicine , Volume 7 , Issue 1 , February 1977 , pp. 159 - 162
Copyright
Copyright © Cambridge University Press 1977

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References

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