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The pineal and psychiatry: still fumbling in the dark?1

Published online by Cambridge University Press:  09 July 2009

P. M. Grasby  and
P J. Cowen
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Abstract

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Type
Editorial
Information
Psychological Medicine , Volume 17 , Issue 4 , November 1987 , pp. 817 - 820
Copyright
Copyright © Cambridge University Press 1987

References

Arato, M., Grof, E., Grof, P., Laszlo, I. & Brown, G. M. (1985). In The Pineal Gland: Endocrine Aspects (ed. Brown, G. M. & Wainwright, S. D.), pp. 277–282. Pergamon Press: Oxford.Google Scholar
Arendt, J. (1986). Assay of melatonin and its metabolites: results in normal and unusual environments. Journal of Neural Transmission Suppl. 21, 11–33.Google Scholar
Arendt, J. & Wilkinson, M. (1979). In Methods of Hormone Radioimmunoassay (ed. Jaffe, B. & Behrman, H.), pp. 101–119. Academic Press: New York.Google Scholar
Arendt, J., Hampton, S., English, J., Kwasowski, P. & Marks, V. (1982). 24-hour profiles of melatonin, cortisol, insulin, C-peptide and GIP following a meal and subsequent fasting. Clinical Endocrinology 16, 89–95.CrossRefGoogle ScholarPubMed
Arendt, J., Symons, A. M., Laud, C. A. & Pryde, S. J. (1983). Melatonin can induce early onset of the breeding season in ewes. Journal of Endocrinology 97, 395–400CrossRefGoogle ScholarPubMed
Arendt, J., Aldhous, M. & Marks, V. (1986). Alleviation of jet lag by melatonin: preliminary results of controlled double blind trail. British Medical Journal 292, 1170.Google Scholar
Axelrod, J. (1974). The pineal gland: a neurochemical transducer. Science 184, 1341–1348.Google Scholar
Brown, R., Kocsis, J. H., Caroff, S., Amsterdam, J., Winokur, A., Stokes, P. E. & Frazer, A. (1985). Differences in nocturnal melatonin secretion between melancholic depressed patients control subjects. American Journal of Psychiatry 142, 811–816.Google Scholar
Claustrat, B., Chazot, G., Brun, J., Jordan, D. & Sassolas, G. (1984). A chronobiological study of melatonin and cortisol secretion in depressed subjects: plasma melatonin, a biochemical marker in major depression. Biological Psychiatry 19, 1215–1229.Google Scholar
Cowen, P. J., Fraser, S., Sammons, R. & Green, A. R. (1983 a). Atenolol reduces plasma melatonin concentration in man. British Journal of Clinical Pharmacology 15, 579–581.Google Scholar
Cowen, P. J., Fraser, S., Grahame-Smith, D. G, Green, A. R. & Stanford, C. (1983 b). The effect of chronic antidepressant administration on beta-adrenoceptor function of the rat pineal. British Journal of Pharmacology 78, 89–96CrossRefGoogle ScholarPubMed
Cowen, P. J., Bevan, J. S., Gosden, B. & Elliott, S. A. (1985 a). Treatment with β-adrenoceptor blockers reduces plasma melatonin concentration. British Journal of Clinical Pharmacology 19, 258–260.CrossRefGoogle ScholarPubMed
Cowen, P. J., Green, A. R., Grahame-Smith, D. G. & Braddock, L. E. (1985 b). Plasma melatonin during desmethylimipramine treatment: evidence for changes in noradrenergic transmission. British Journal of Clinical Pharmacology 19, 799–805.CrossRefGoogle ScholarPubMed
Franey, C., Aldhous, M., Burton, S, Checkley, S. & Arendt, J. (1986). Acute treatment with desipramine stimulates melatonin and 6-sulphatoxy melatonin production in man. British Journal Clinical Pharmacology 22, 73–79.CrossRefGoogle Scholar
Fraser, S., Cowen, P, Franklin, M., Franey, C. & Arendt, J. (1983 a). Direct radioimmunoassay for melatonin in plasma. Clinical Chemistry 29, 396–397.CrossRefGoogle ScholarPubMed
Fraser, S., Cowen, P., Franklin, M. & Lewy, A. J. (1983 b). Direct radioimmunoassay and gas chromatography-mass spectrometry compared for determination of melatonin in plasma. Clinical Chemistry 19, 1703–1704.Google Scholar
Frazer, A., Brown, R., Kocsis, J., Caroff, S., Amsterdam, J, Winokur, A., Sweeney, J. & Stokes, P. (1986). Patterns melatonin rhythms in depression. Journal of Neural Transmission Suppl. 21, 269–290.Google Scholar
Heydorn, W. E., Brunswick, D. J. & Frazer, A. (1982). Effect treatment of rats with antidepressants on melatonin concentrations in the pineal gland and serum. Journal of Pharmacology and Experimental Therapeutics 222, 534–544.Google ScholarPubMed
Lewy, A. J., Wehr, T. A., Goodwin, F. K., Newsome, D. A.Markey, S. P. (1980). Light suppresses melatonin secretion humans. Science 210, 1267–1269.Google Scholar
Lewy, A. J., Nurnberger, J. I., Wehr, T. A., Pack, D., Becker, L. E., Powell, R. L. & Newsome, D. A. (1985). Supersensitivity to light: possible trait marker for manic depressive illness. American Journal of Psychiatry 142, 725–727.Google ScholarPubMed
Moore, R. Y. (1978). In Frontiers in Neuroendocrinology (ed. Ganong, W. F. & Martin, L.), vol. 5, pp. 185–206. Raven Press: New York.Google Scholar
Moyer, J. A., Greenberg, L. H., Frazer, A. & Weiss, B. (1981). Subsensitivity of the beta-adrenergic receptor linked adenylate cyclase system of rat pineal gland following repeated treatment with desmethylimipramine and nialamide. Molecular Pharmacology 19, 187–193.Google Scholar
Mullen, P. & Silman, R. (1977). The pineal and psychiatry: a review. Psychological Medicine 7, 407–417.Google Scholar
Murphy, D. L., Tamarkin, L., Sunderland, T., Garrick, N. A. & Cohen, R. M. (1986). Human plasma melatonin is elevated during treatment with the monoamine oxidase inhibitors clorgyline and tranylcypromine but not deprenyl. Psychiatry Research 17, 119–127.Google Scholar
Nair, N. P. V., Hariharasubramanian, N. & Pilapil, C. (1984). Circadian rhythm of plasma melatonin in endogenous depression. Progress Neuro-Psychopharmacology and Biological Psychiatry 8, 715–718.CrossRefGoogle ScholarPubMed
Nair, N. P. V., Hariharasubramanian, N., Pilapil, C., Isaac, I. & Thavundayil, J. X. (1986). Plasma melatonin – an index of brain aging in humans? Biological Psychiatry 21, 141–150.Google Scholar
Pandey, G. N., Heinze, W. J., Brown, B. D. & Davis, J. M. (1979). Electroconvulsive shock treatment decreases beta-adrenergic sensitivity in rat brain. Nature 280, 234–235.CrossRefGoogle ScholarPubMed
Redman, J., Armstrong, S. & Ng, K. T. (1983). Free running activity rhythms in the rat: entertainment by melatonin. Science 219, 1089–1091.Google Scholar
Rosenthal, N. E., Sack, D. A., Gillin, J. C., Lewy, A. J., Goodwin, F. K., Davenport, Y., Mueller, P. S., Newsome, D. A. & Wehr, T. A. (1984). Seasonal affective disorder. Archives of General Psychiatry 41, 72–80.Google Scholar
Rosenthal, N. E., Sack, D. A., Jacobsen, F. M., James, S. P., Parry, B. L., Arendt, J., Tamarakin, L. & Wehr, T. A. (1986). Melatonin in seasonal Affective Disorder and phototherapy. Journal of Neural Transmission, Suppl. 21, 257–267.Google ScholarPubMed
Sack, R. L. & Lewy, A. J. (1986). Desmethylimipramine treatment increases melatonin production in humans. Biological Psychiatry 21, 406–410.Google Scholar
Sellinger-Barnett, M. M., Mendels, J. & Frazer, A. (1980). The effect of psychoactive drugs on beta-adrenergic receptor binding sites in rat brain. Neuropharmacology 19, 447–454.Google Scholar
Sulser, F. (1979). New perspectives on the mode of action of antidepressant drugs. Trends in Pharmacological Sciences 1, 92–94.Google Scholar
Thompson, C., Mezey, G., Corn, T., Franey, J., English, J., Arendt, J. & Checkley, S. A. (1985). The effect of desipramine upon melatonin and cortisol secretion in depressed and normal subjects. British Journal of Psychiatry 147, 389–393.Google Scholar
Thompson, C., Franey, C., Arendt, J. & Checkley, S. A. (1987). A comparison of melantonin secretion in depressed patients and normal subjects. British Journal of Psychiatry (in the press).Google Scholar
Vaughan, G. M., Pelham, R. W., Pang, S. F., Loughlin, L. L., Wilson, K. M., Sandock, K. L., Vaughan, M. K., Koslow, S. H. & Reiter, R. J. (1976). Nocturnal elevation of plasma melatonin and urinary 5-hydroxyindoleacetic acid in young men: attempts at modification by brief changes in environmental lighting and sleep and by autonomic drugs. Journal of Clinical Endocrinology and Metabolism 42, 752–764.Google Scholar
Waldhauser, F., Weissenbacher, G., Zeitlhuber, U., Waldhauser, M., Frisch, H. & Wurtman, R., (1984). Fall in nocturnal serum melatonin levels during prepuberty and pubescence. Lancet i, 362–365.Google Scholar
Webley, G. E. & Leidenberger, F. (1986). The circadian pattern of melatonin and its positive relationship with progesterone in women. Journal of Clinical Endocrinology and Metabolism 63, 323–328.CrossRefGoogle ScholarPubMed
Wehr, T. A., Jacobsen, F. M., Sack, D. A., Arendt, J., Tamarkin, L. & Rosenthal, N. E. (1986). Phototherapy of Seasonal Affective Disorder. Archives of General Psychiatry 43, 870–875.Google Scholar
Wetterberg, L (1983). The relationship between the pineal gland and the pituitary – adrenal axis in health, endocrine and psychiatric conditions Psychoneuroendocrinology 8, 75–80.Google Scholar