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Medical Research Council Unit for Metabolic Studies in Psychiatry, Sheffield

Published online by Cambridge University Press:  09 July 2009

F. A. Jenner
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Extract

The Medical Research Council Unit for Metabolic Studies in Psychiatry was set up at Middle-wood Hospital, Sheffield, in 1967. It was to a considerable extent a continuation of the Medical Research Council Unit for the Chemical Pathology of Mental Disorders which had been associated with the Department of Physiology in the University of Birmingham under the direction of Professor I. E. Bush. The latter unit had in its turn largely corne from a group headed by Sir George Pickering at Oxford.

Type
Research Report
Information
Psychological Medicine , Volume 3 , Issue 3 , August 1973 , pp. 379 - 384
Copyright
Copyright © Cambridge University Press 1973

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References

BIBLIOGRAPHY AND REFERENCES

Bailey, E., and Chapman, J. A. (1973). The use of chloro-methyldimethylsilyl ether derivatives for the analysis of hydroxylatcd steroids by gas chromatography-mass spectrometry. Analytical Chemistry, (in press).Google Scholar
Bailey, E., Fenoughty, M., and Wheeler, M. J. (1973). The group estimation of urinary II-oxy-17-hydroxycortico-steroids using gas-liquid chromatography. Biochemical Medicine. 7, 1–13.CrossRefGoogle Scholar
Bailey, E., Jenner, F. A., and Wheeler, M. J. (1971). Renal function during the stages of sleep. Journal of Physiology, 218, 40–42.Google ScholarPubMed
Birch, N. J. (1970). Effects of lithium on plasma magnesium. British Journal of Psychiatry, 116, 461.CrossRefGoogle ScholarPubMed
Birch, N. J., and Jenner, F. A. (1972). The distribution of lithium and its effects on the distribution and excretion of other ions in the rat. (Submitted for publication.) (See Birch, N. J., Ph.D. Thesis, University of Sheffield.)Google Scholar
Bond, P. A. (1972). The determination of 4-hydroxy-3-methoxyphenylethylene glycol in urine and CSF using gas chromatography. Biochemical Medicine, 6, 36–45.CrossRefGoogle Scholar
Bond, P. A., Jenner, F. A., Lee, C. R., Lenton, E., Pollitt, R. J., and Sampson, G. A., (1972). The effect of lithium salts on the urinary excretion of α-oxoglutarate in man. British Journal of Pharmacology. 46, 116–123.CrossRefGoogle ScholarPubMed
Bond, P. A., Jenner, F. A., and Sampson, G., A. (1972). Daily variations of the urine content of 3-methoxy-4-hydroxyphenylglycol in two manie-depressive patients. Psychological Medicine, 2, 81–85.CrossRefGoogle Scholar
Chard, N., Grant, L., and Jenner, F. A. (1966). A device for timing micturitionof rats. Journal of Physiology, 184, 10–11.Google Scholar
Crane, C. W., Gay, W. M. B., and Jenner, F. A. (1969). Urea production from labelled ammonia in argininosuccinic aciduria. Clinica et Chimica Acta, 24, 445–448.CrossRefGoogle ScholarPubMed
Empson, J. A. C., and Clarke, P. R. F. (1970). Rapid eye movements and remembering. Nature, 227, 287–288.CrossRefGoogle ScholarPubMed
Fell, V., and Pollitt, R. J. (1971). The use of diagonal electrophoresis to demonstrate some unusual urinary homocystine metabolitcs in homocystinuria. In Inherited Disorders of Sulphur Metabolisin, Proceedings of the Eighth Symposium of the Society for the Study of Inborn Errors of Metabolism, pp. 232–234. Edited by Carson, N. A. J. and Raine, D. N.. Churchill, Livingstone: Edinburgh.Google Scholar
Garston, J. B., Gordon, R. R., Hart, C. T., and Pollitt, R. J. (1970). An unusual case of homocystinuria. British Journal of Ophthalnology, 54, 248–251.CrossRefGoogle ScholarPubMed
Giessing, L. R., Harding, G. F. A., Jenner, F. A., and Johannessen, N. B. (1967). The EEG in three cases of periodic catatonia. British Journal of Psychiatry, 113, 1271–1282.CrossRefGoogle Scholar
Goodwin, J. C., and Jenner, F. A. (1967). The cyclical excretion of a sodium thioglycollalc-rcsistant Antidiuretic factor by a periodic psychotic. Journal of Endocrinology, 38, xxiv.Google Scholar
Goodwin, J. C., and Jenner, F. A. (1967). The antidiuretic activity of human urine on Controlled diets with varying sodium chloridc and Water content. Journal of Physiology, 189, pp. 62–63.Google ScholarPubMed
Goodwin, J. C., Jenner, F. A., Lobban, M. C., and Sheridan, M. (1965). Renal rhythms in a patient with a 48 hr cycle of psychosis during a period of life on an abnormal time routine. Journal of Physiology, 176, pp. 16–17.Google Scholar
Goodwin, J. C., Jenner, F. A., and Slater, S. E. (1968). The diurnal pattern of excretion of antidiuretic hormone. Journal of Physiology, 196, pp. 112–113.Google ScholarPubMed
Grant, L. (1966). A useful rat head holder for cerebral surgery. Medical and Biological Engineering, 4, 401–402.CrossRefGoogle ScholarPubMed
Grant, L., Chard, N., and Jenner, F. A. (1968). An automated System for longterm studies of animal activity. Animal Behaviour, 16, 589.Google Scholar
Grant, L., and Haddrell, D. (1971). An operating table plus head holder for rats. Medical and Biological Engineering, 9, 703–704.CrossRefGoogle ScholarPubMed
Grant, L., Hopkinson, P., Jennings, G., and Jenner, F. A. (1971). Period of adjustment of rats used for experimental studies. Nature, 232, 135.CrossRefGoogle ScholarPubMed
Grant, L., Jenner, F. A., and Willey, B. (1966). Pinealectomy in the rat. Journal of Physiology, 182, p. 24.Google Scholar
Hanna, S. M., Jenner, F. A., Pearson, I. B., Sampson, G. A., and Thompson, E. A. (1972). The therapeutic effect of lithium carbonate on a patient with a forty-eight hour periodic psychosis. British Journal of Psychiatry, 121, 271–280.CrossRefGoogle ScholarPubMed
Harding, G., Jeavons, P. M., Jenner, F. A., Drummond, P., Sheridan, M. and Howells, G. W. (1966). The electro-encephalogram in three cases of periodic psychoses. Electroencepholography and Clinical Neurophysiology, 21, 59–66.CrossRefGoogle Scholar
Harris, C. A., and Jenner, F. A. (1969a). The ionic specificity of lithium as an inhibitor of the action of vasopressin. Journal of Physiology, 203, pp. 73–74.Google ScholarPubMed
Harris, C. A., and Jenner, F. A. (1969b). The inhibition of the action of vasopressin by lithium ions. Journal of Physiology, 200, p. 59.CrossRefGoogle ScholarPubMed
Harris, C. A., and Jenner, F. A. (1971a). The inhibition by lithium ions of the action of vasopressin and cyclic A.M.P. on water transport in the toad's bladder. Journal de Pharmacologie, 2, 215–216.Google Scholar
Harris, C. A., and Jenner, F. A. (1971b). The irrelevance of total body and serum lithium levels in the inhibition of the action of vasopressin by lithium. Journal of Physiology, 214, 43–44.Google ScholarPubMed
Harris, C. A., and Jenner, F. A. (1972). Some aspects of the inhibition of the action of antidiuretic hormone by lithium ions in the rat kidney and bladder of the toad Bufo marinus. British Journal of Pharmacology, 44, 223–232.CrossRefGoogle ScholarPubMed
Jenner, F. A. (1970). The physiology and biochemistry of periodic psychoses including periodic catatonia. In Biochemistry, Schizophrenias and Affective Illnesses, pp. 29–42. Edited by Himwich, H. E.. Williams and Wilkins: Baltimore.Google Scholar
Jenner, F. A. (1967). Studies on periodic catatonia. In Amines and Schizophrenia, pp. 115–121. Edited by Himwich, H. E., Kety, S. S., and Smythies, J. R.. Pergamon Press: Oxford.CrossRefGoogle Scholar
Jenner, F. A. (1968). Periodic psychoses in the light of biological rhythm research. International Review of Neurobiology, 11, 129–169.CrossRefGoogle ScholarPubMed
Jenner, F. A. (1965). A psychotic analogue. In Biomechanics and Related Bio-engineering Topics, Proceedings of a Symposium, Glasgow, 1964. pp. 467–473. Edited by Kenedi, R. M.. Pergamon Press: Oxford.Google Scholar
Jenner, F. A., Gjessing, L. R., Cox, J. R., Davies-Jones, A., Hullin, R. P., and Hanna, S. M. (1967). A manic depressive psychosis with a persistent forty-eight hour cycle. British Journal of Psychiatry, 113, 895–910.CrossRefGoogle ScholarPubMed
Jenner, F. A., Goodwin, J. C., Sheridan, M., Tauber, I. J., and Lobban, M. C. (1968). The effect of an altered time regime on biological rhythms in a 48-hour periodic psychosis. British Journal of Psychiatry, 114, 215–224.CrossRefGoogle Scholar
Jenner, F. A., and Pollitt, R. J. (1967). Large quantities of 2-acetamido-1(β-L-aspartamido)-1,2-dideoxyglucose in the urine of mentally retarded siblings. Biochemical Journal, 103, pp. 48P–49P.Google Scholar
Kinson, G. A., Singer, B., and Grant, L. (1968). Tissue weights and adrenocortical function at various time intervals after pinealectomy in the rat. In Third International Congress of Endocrinology, Mexico, 1968. Abstracts of Brief Communications, p. 179. Edited by Gual, C.. International Congress Series No. 157. Excerpta Medica: Amsterdam.Google Scholar
Kinson, G. A., Singer, B., and Grant, L. (1968). Adrenocortical hormone swcretion at various time intervals after pinealectomy in the rat. General and Comparative Endocrinology, 10, 447–449.CrossRefGoogle Scholar
Lee, C. R., and Pollitt, R. J. (1970b). The anhydrides of argininosuccinic acid. Tetrahedron, 26, 3113–3121.CrossRefGoogle ScholarPubMed
Lee, C. R., and Pollitt, R. J. (1972a). The estimation of glutarate in urine using gas chromatography mass spectrometry with an internaisotopic standard. Biochemical Medicine, 6, 536–542.CrossRefGoogle ScholarPubMed
Lee, C. R., and Pollitt, R. J. (1972b). New derivatives of argininosuccinic acid in the urine of a patient with arginino-succinicaciduria. Biochemical Journal, 126, 79–87.CrossRefGoogle Scholar
Lee, C. R. and Pollitt, R. J. (1973). The eflect of lithium salts on the urinary excretion of somc dicarboxylic acids. Biochemical Society Transactions, 1, 108–109.CrossRefGoogle Scholar
Pearson, I. B., and Jenner, F. A. (1971). Lithium in psychiatry. Nature, 232, 532–533.CrossRefGoogle ScholarPubMed
Pollitt, R. J., Jenner, F. A., and Merskey, H. (1968). Aspartylglycosaminuria. An inborn error of metabolism associatcd with mental defect. Lancet, 2, 253–255.CrossRefGoogle ScholarPubMed
Pollitt, R. J., and Jenner, F. A. (1969a). Enzymatic eleavage of 2-acetamido-1-(β-L-aspartamido)-1,2-dideoxy-β-D-glu-cose by human plasma and seminal Fluid. Failure to detect the heterozygous state for aspartylglycosaminuria. Clinica Chimica Acta, 25, 413–416.CrossRefGoogle Scholar
Pollitt, R. J., and Jenner, F. A. (1969b). Two new inborn errors of metabolism? In Some Inherited Disorders of Brain and Muscle. Proceedings of the Fifth Symposium of the Society for the Study of Inborn Errors of Metabolism, pp. 78–81. Edited by Allan, J. D. and Raine, D. N.. Living-stone: Edinburgh.Google Scholar
Pollitt, R. J., and Jenner, F. A. (1971). Aspartylglycosaminuria—a new inborn error possibly due to a lysosomal enzyme defect. In Cellular Organelles and Membranes in Mental Retardation, pp. 95–106. Edited by Benson, P. F.. Churchill Livingstone: Edinburgh.Google Scholar
Pollitt, R. J., Jenner, F. A., and Davies, M. (1968). Sibs with mental and physical retardation and trichorrhexis nodosa with abnormal amino acid composition of the hair. Archives of Disease in Childhood, 43, 211–216.CrossRefGoogle ScholarPubMed
Pollitt, R. J., and Pretty, K. M. (1972). Glycoasparagines in the urine of patients with aspartylglycosaminuria. Biochemical Journal, 128, 129P–130P.CrossRefGoogle ScholarPubMed
Pollitt, R. J., and Stonier, P. D. (1971). Proteins of normal hair and of cystine-deficient hair from mentally retarded siblings. Biochemical Journal, 122, 433–444.CrossRefGoogle ScholarPubMed
Rowe, Dorothy (1972). The Individual Microcosm. Ph.D. Thesis; University of Sheffield.Google Scholar