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The impact of parenthood on risk of registration for alcohol use disorder in married individuals: a Swedish population-based analysis

Published online by Cambridge University Press:  25 October 2018

Kenneth S. Kendler ,
Sara Larsson Lönn ,
Jessica E. Salvatore ,
Jan Sundquist  and
Kristina Sundquist
Kenneth S. Kendler*
Affiliation:
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA Department of Psychiatry, Virginia Commonwealth University, Richmond VA, USA Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA
Sara Larsson Lönn
Affiliation:
Center for Primary Health Care Research, Lund University, Malmö, Sweden
Jessica E. Salvatore
Affiliation:
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA Department of Psychology, Virginia Commonwealth University, Richmond VA, USA
Jan Sundquist
Affiliation:
Center for Primary Health Care Research, Lund University, Malmö, Sweden Department of Family Medicine and Community Health, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, USA Department of Functional Pathology, Center for Community-based Healthcare Research and Education (CoHRE), School of Medicine, Shimane University, Shimane, Japan
Kristina Sundquist
Affiliation:
Center for Primary Health Care Research, Lund University, Malmö, Sweden Department of Family Medicine and Community Health, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, USA Department of Functional Pathology, Center for Community-based Healthcare Research and Education (CoHRE), School of Medicine, Shimane University, Shimane, Japan
*
Author for correspondence: Kenneth S. Kendler, E-mail: [email protected]
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Abstract

Background

Although being married with children is associated with a reduced rate of alcohol use disorder (AUD), is this finding independent of a marital effect, different in mothers and fathers and potentially causal in effect.

Methods

Using Cox proportional hazards, we examined, in 1 252 237 married individuals, the association between a resident younger and older child and risk for AUD registration in national medical, criminal, and pharmacy registers. Using logistic regression, we analyzed, in 600 219 parents, within-person models comparing risk for AUD prior to first pregnancy v. with young children. We examined whether risk for AUD in 1302 parents after a first spousal AUD registration was reduced by having a young resident child.

Results

Compared with childless married individuals, resident younger children were associated with a reduced risk for AUD in mothers [hazard ratio (HR) 0.36, 95% confidence interval 0.31–0.41] and fathers (HR 0.66, 0.60–0.73). The reduced risk was attenuated but still significant for older children. Within-person models confirmed the protective effect of young children in mothers [odds ratio (OR) 0.49, 0.30–0.80] but yielded inconclusive results in fathers (OR 0.85, 0.58–1.25). After a first spousal registration for AUD, a resident young child was associated with a substantial reduction in risk for mothers and a weaker marginal effect in fathers.

Conclusion

In married individuals, resident children are associated with a reduction in basal risk for AUD which is stronger in mothers than fathers and with younger v. older children. This effect is also evident during high-risk periods. In mothers, our results are consistent with a largely causal effect.

Keywords

Alcohol use disorderchildrenepidemiologymarriage
Type
Original Articles
Information
Psychological Medicine , Volume 49 , Issue 13 , October 2019 , pp. 2141 - 2148
Copyright
Copyright © Cambridge University Press 2018 

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References

Bachman, JG, Wadsworth, KN, O'Malley, PM, Johnston, LD and Schulenberg, JE (1997) Smoking, Drinking, and Drug Use in Young Adulthood: The Impacts of New Freedoms and New Responsibilities. Mahwah, NJ: Lawrence Erlbaum Associates.Google Scholar
Chilcoat, HD and Breslau, N (1996) Alcohol disorders in young adulthood: effects of transitions into adult roles. Journal of Health and Social Behavior 37, 339–349.Google Scholar
Christie-Mizell, CA and Peralta, RL (2009) The gender gap in alcohol consumption during late adolescence and young adulthood: gendered attitudes and adult roles. Journal of Health and Social Behavior 50, 410–426.Google Scholar
Craig, L and Bittman, M (2008) The incremental time costs of children: an analysis of children's impact on adult time use in Australia. Feminist Economics 14, 59–88.Google Scholar
Fergusson, DM, Boden, JM and John, HL (2012) Transition to parenthood and substance use disorders: findings from a 30-year longitudinal study. Drug and Alcohol Dependence 125, 295–300.Google Scholar
Hajema, KJ and Knibbe, RA (1998) Changes in social roles as predictors of changes in drinking behaviour. Addiction 93, 1717–1727.Google Scholar
Heath, AC, Bucholz, KK, Madden, PA, Dinwiddie, SH, Slutske, WS, Bierut, LJ, Statham, DJ, Dunne, MP, Whitfield, JB and Martin, NG (1997) Genetic and environmental contributions to alcohol dependence risk in a national twin sample: consistency of findings in women and men. Psychological Medicine 27, 1381–1396.Google Scholar
Kendler, KS, Ji, J, Edwards, AC, Ohlsson, H, Sundquist, J and Sundquist, K (2015) An extended Swedish national adoption study of alcohol use disorder. JAMA Psychiatry 72, 211–218.Google Scholar
Kendler, KS, Lonn, SL, Salvatore, J, Sundquist, J and Sundquist, K (2016a) Effect of marriage on risk for onset of alcohol use disorder: a longitudinal and co-relative analysis in a Swedish national sample. American Journal of Psychiatry 173, 911–918.Google Scholar
Kendler, KS, PirouziFard, M, Lonn, S, Edwards, AC, Maes, HH, Lichtenstein, P, Sundquist, J and Sundquist, K (2016b) A national Swedish twin-sibling study of alcohol use disorders. Twin Research and Human Genetics 19, 430–437.Google Scholar
Kendler, KS, Lonn, SL, Salvatore, J, Sundquist, J and Sundquist, K (2017) Divorce and the onset of alcohol use disorder: a Swedish population-based longitudinal cohort and co-relative study. American Journal of Psychiatry 174, 451–458.Google Scholar
Kendler, KS, Lönn, SL, Salvatore, J, Sundquist, J and Sundquist, K (2018) The origin of spousal resemblance for alcohol use disorder. JAMA Psychiatry 75, 280–286.Google Scholar
Koob, GF and Volkow, ND (2016) Neurobiology of addiction: a neurocircuitry analysis. The Lancet Psychiatry 3, 760–773.Google Scholar
Kringlen, E, Torgersen, S and Cramer, V (2001) A Norwegian psychiatric epidemiological study. American Journal of Psychiatry 158, 1091–1098.Google Scholar
Kuntsche, S, Knibbe, RA and Gmel, G (2009) Social roles and alcohol consumption: a study of 10 industrialised countries. Social Science and Medicine 68, 1263–1270.Google Scholar
Leonard, KE and Eiden, RD (2007) Marital and family processes in the context of alcohol use and alcohol disorders. Annual Review of Clinical Psychology 3, 285–310.Google Scholar
Levy, F, Le Strat, Y, Hoertel, N, Ancelet, C and Dubertret, C (2018) Childbirth and alcohol consumption impact of recent childbirth on alcohol consumption. Journal of Child and Family Studies 27, 2245–2253.Google Scholar
Little, M, Handley, E, Leuthe, E and Chassin, L (2009) The impact of parenthood on alcohol consumption trajectories: variations as a function of timing of parenthood, familial alcoholism, and gender. Developmental Psychopathology 21, 661–682.Google Scholar
Merline, AC, O'Malley, PM, Schulenberg, JE, Bachman, JG and Johnston, LD (2004) Substance use among adults 35 years of age: prevalence, adulthood predictors, and impact of adolescent substance use. American Journal of Public Health 94, 96–102.Google Scholar
Neve, RJ, Lemmens, PH and Drop, MJ (2000) Changes in alcohol use and drinking problems in relation to role transitions in different stages of the life course. Substance Abuse 21, 163–178.Google Scholar
O'Malley, PM (2004) Maturing out of problematic alcohol use. Alcohol Research & Health 28, 202–204.Google Scholar
Prescott, CA and Kendler, KS (1999) Genetic and environmental contributions to alcohol abuse and dependence in a population-based sample of male twins. American Journal of Psychiatry 156, 34–40.Google Scholar
R Development Core Team (2017) R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing. Online Source.Google Scholar
Rebora, P, Salim, A and Reilly, M (2014) bshazard: Nonparametric Smoothing of the Hazard Function. R package version 1.0. Vienna, Austria: The R Foundation for Statistical Computing. Online Source.Google Scholar
Rutter, M (1996) Transitions and turning points in developmental psychopathology: as applied to the age span between childhood and mid-adulthood. International Journal of Behavioral Development 19, 603–626.Google Scholar
Schulenberg, J, Maggs, JL and O'Malley, PM (2003) How and why the understanding of developmental continuity and discontinuity is important: the sample case of long-term consequences of adolescent substance use. In Mortimer, JT & Shanaham, M (eds), Handbook of the Life Course. New York: Kluwer Academic/Plenum Publishers, pp. 413–436.Google Scholar
Staff, J, Schulenberg, JE, Maslowsky, J, Bachman, JG, O'Malley, PM, Maggs, JL and Johnston, LD (2010) Substance use changes and social role transitions: proximal developmental effects on ongoing trajectories from late adolescence through early adulthood. Developmental Psychopathology 22, 917–932.Google Scholar
Staff, J, Greene, KM, Maggs, JL and Schoon, I (2013) Family transitions and changes in drinking from adolescence through mid-life. Addiction 109, 227–236.Google Scholar
Statistics Sweden (2016) Women and men in Sweden: Facts and Figures 2016. Örebro: Statistics Sweden, Population Statistics Unit. SE-701 89. Online Source.Google Scholar
Tyssen, R, Vaglum, P, Aasland, OG, Gronvold, NT and Ekeberg, O (1998) Use of alcohol to cope with tension, and its relation to gender, years in medical school and hazardous drinking: a study of two nation-wide Norwegian samples of medical students. Addiction 93, 1341–1349.Google Scholar
Verges, A, Jackson, KM, Bucholz, KK, Grant, JD, Trull, TJ, Wood, PK and Sher, KJ (2012) Deconstructing the age-prevalence curve of alcohol dependence: why ‘maturing out’ is only a small piece of the puzzle. Journal of Abnormal Psychology 121, 511–523.Google Scholar
Verhulst, B, Neale, MC and Kendler, KS (2015) The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies. Psychological Medicine 45, 1061–1072.Google Scholar
Yamaguchi, K and Kandel, DB (1985) On the resolution of role incompatibility – a life event history analysis of family roles and marijuana use. American Journal of Sociology 90, 1284–1325.Google Scholar
Yule, GU (1912) On the methods of measuring association between two attributes. Journal of the Royal Statistical Society 75, 579–652.Google Scholar
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