Published online by Cambridge University Press: 09 July 2009
Sixty years ago the distinguished epidemiologist Joseph Goldberger, following his outstanding achievements in clarifying the causes of pellagra, was offered a large research grant to investigate schizophrenia. He responded to the proposal by studying the available evidence concerning the schizophrenic syndrome and then politely declined to take up the challenge. ‘In five or more years’, he wrote, ‘I could probably find out nothing. Much work will be needed on the physiology of the central nervous system and on many collateral problems before dementia praecox can be understood’ (Parsons, 1943).
Part of the William Withering lecture on ‘The Epidemiology of Madness’ delivered at the University of Birmingham, March, 1992.