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The global burden of anxiety disorders in 2010

Published online by Cambridge University Press:  22 January 2014

A. J. Baxter ,
T. Vos ,
K. M. Scott ,
A. J. Ferrari  and
H. A. Whiteford
A. J. Baxter*
Affiliation:
School of Population Health, University of Queensland, Herston, Australia Queensland Centre for Mental Health Research, Wacol, Australia
T. Vos
Affiliation:
University of Washington, Institute for Health Metrics and Evaluation, Seattle, WA, USA
K. M. Scott
Affiliation:
Department of Psychological Medicine, University of Otago, Dunedin, New Zealand
A. J. Ferrari
Affiliation:
School of Population Health, University of Queensland, Herston, Australia Queensland Centre for Mental Health Research, Wacol, Australia
H. A. Whiteford
Affiliation:
School of Population Health, University of Queensland, Herston, Australia Queensland Centre for Mental Health Research, Wacol, Australia
*
*Address for correspondence: A. J. Baxter, M.P.H., Queensland Centre for Mental Health Research, University of Queensland, Brisbane, QLD 4074, Australia. (Email: [email protected])
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Abstract

Background

Despite their high prevalence, the global burden of anxiety disorders has never been calculated comprehensively. The new Global Burden of Disease (GBD) study has estimated burden due to morbidity and mortality caused by any anxiety disorder.

Method

Prevalence was estimated using Bayesian meta-regression informed by data identified in a systematic review. Years of life lived with disability (YLDs) were calculated by multiplying prevalent cases by an average disability weight based on severity proportions (mild, moderate and severe). Disability-adjusted life years (DALYs) were then calculated and age standardized using global standard population figures. Estimates were also made for additional suicide mortality attributable to anxiety disorders. Findings are presented for YLDs, DALYs and attributable burden due to suicide for 21 world regions in 1990 and 2010.

Results

Anxiety disorders were the sixth leading cause of disability, in terms of YLDs, in both high-income (HI) and low- and middle-income (LMI) countries. Globally, anxiety disorders accounted for 390 DALYs per 100 000 persons [95% uncertainty interval (UI) 191–371 DALYs per 100 000] in 2010, with no discernible change observed over time. Females accounted for about 65% of the DALYs caused by anxiety disorders, with the highest burden in both males and females experienced by those aged between 15 and 34 years. Although there was regional variation in prevalence, the overlap between uncertainty estimates means that substantive differences in burden between populations could not be identified.

Conclusions

Anxiety disorders are chronic, disabling conditions that are distributed across the globe. Future estimates of burden could be further improved by obtaining more representative data on severity state proportions.

Keywords

Anxiety disordersburden of diseasedisabilityepidemiologyglobal healthpublic health
Type
Original Articles
Information
Psychological Medicine , Volume 44 , Issue 11 , August 2014 , pp. 2363 - 2374
Copyright
Copyright © Cambridge University Press 2014 

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