Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-17T14:53:45.805Z Has data issue: false hasContentIssue false

Genetic influences on life events in childhood

Published online by Cambridge University Press:  09 July 2009

Anita Thapar*
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine, Cardiff
Peter McGuffin
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine, Cardiff
*
1Address for correspondence: Dr Anita Thapar, Department of Child and Adolescent Psychiatry, Royal Manchester Children's Hospital, Pendlebury, Manchester M27 4HA.

Synopsis

Until recently, life events were considered as chance occurrences. However, there is now increasing evidence that reported life events, at least in adult life are not random. Life events not only tend to cluster in families but also appear to be influenced by genetic factors. The aim of this study was to investigate whether genetic factors also influence reported life events in childhood using a systematically ascertained sample of 376 twin pairs aged 8 to 17. Overall, reported life events in this younger population were found to be heritable. However, the degree of genetic and environmental influence appeared to vary across the sexes, at least for parent-rated life events and according to whether life events were rated by the parents or the children themselves. Genetic influences appeared to be more important for self reports, suggesting that individual differences in cognition play a role in reporting life events.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Andrews, J., Davies, K., Chalmers, I. & Campbell, H. (1986). The Cardiff Births Survey. In Genetic and Population Studies in Wales (ed. Harper, P. S. and Sunderland, E.), pp. 317341. University of Wales Press: Cardiff.Google Scholar
Beardsall, L. & Dunn, J. (1992). Adversities in childhood: siblings' experiences, and their relations to self-esteem. Journal of Child Psychology and Psychiatry 33, 349359.CrossRefGoogle ScholarPubMed
Brown, G. W. & Harris, T. O. (1989). Depression. In Life Events and Illness (ed. Brown, G. W. and Harris, T. O.), pp. 4993. Guilford Press: New York.Google Scholar
Brown, G. W., Harris, T. O. & Hepworth, C. (1994). Life events and endogenous depression. Archives of General Psychiatry 51, 525534.CrossRefGoogle ScholarPubMed
Cohen, D. J., Dibble, E., Grawe, J. M. & Pollin, W. (1975). Reliably separating identical from fraternal twins. Archives of General Psychiatry 32, 13711375.CrossRefGoogle ScholarPubMed
Eaves, L. J., Eysenck, H. J. & Martin, N. (1989). Genes, Culture and Personality. Academic: New York.Google Scholar
Fergusson, D. M. & Horwood, L. J. (1987). Vulnerability to life events exposure. Psychological Medicine 17, 739749.CrossRefGoogle ScholarPubMed
Goodyer, I. M. (1990). Recent life events and psychiatric disorder in school age children. Journal of Child Psychology and Psychiatry 31, 839848.CrossRefGoogle ScholarPubMed
Goodyer, I. M., Kolvin, I. & Gatzanis, S. (1987). The impact of recent life events in psychiatric disorders of childhood and adolescence. British Journal of Psychiatry 151, 179185.CrossRefGoogle ScholarPubMed
Goodyer, I. M., Cooper, P. J., Vize, C. M. & Ashby, L. (1993). Depression in 11–16-year-old girls: the role of past parental psychopathology and exposure to recent life events. Journal of Child Psychology and Psychiatry 34, 11031115.CrossRefGoogle ScholarPubMed
Hewitt, J. K., Silberg, J. L., Neale, M. C., Eaves, L. J. & Erickson, M. (1992). The analysis of parental ratings of Children's; behavior using LISREL. Behavior Genetics 22, 293317.CrossRefGoogle ScholarPubMed
Johnson, J. H. & McCutcheon, S. (1980). Assessing life stress in older children and adolescents: Preliminary findings with the life events checklist. In Stress and Anxiety (ed. Sarasson, I. E. and Spielberger, C. D.), pp. 111125. Hemisphere Publishing Corporation: New York.Google Scholar
Kendler, K. S., Neale, M., Kessler, R., Heath, A. & Eaves, L. (1993). A twin study of recent life events and difficulties. Archives of General Psychiatry 50, 789796.CrossRefGoogle ScholarPubMed
Loehlin, J. C. & Nichols, R. C. (1976). Heredity, Environment and Personality. University of Texas Press: Austin.Google Scholar
McGuffin, P. & Katz, R. (1993). Genes, adversity and depression. In Nature, Nurture and Psychology (ed. Plomin, R. and McClearn, G. E.), pp. 217230. American Psychological Association: Washington, DC.CrossRefGoogle Scholar
McGuffin, P., Katz, R., Aldrich, J. & Bebbington, P. (1988). The Camberwell collaborative depression study. II. Investigation of family members. British Journal of Psychiatry 152, 766774.CrossRefGoogle ScholarPubMed
McGuffin, P., Owen, M. J., O'Donovan, M. C., Thapar, A. & Gottesman, I. I. (1994). Seminars of Psychiatry Genetics. Gaskell: London.Google Scholar
McGuire, S., Neiderhiser, J. M., Reiss, D., Hetherington, E. M. & Plomin, R. (1994). Genetic and environmental influences on perceptions of self-worth and competence in adolescence: a study of twins, full siblings and step-siblings. Child Development 65, 785799.CrossRefGoogle ScholarPubMed
Magnus, K., Diener, E., Fujita, F. & Pavot, W. (1993). Extraversion and neuroticism as predictors of objective life events: a longitudinal analysis. Journal of Personality and Social Psychology 65, 10461053.CrossRefGoogle ScholarPubMed
Neale, M. C. (1991) Mx. Statistical Modeling. Department of Human Genetics, MCV, Richmond, Virginia.Google Scholar
Neale, M. C. & Cardon, L. R. (1992). Methodology for Genetic Studies of Twins and Families. Kluwer Academiemic Publishers: Dordrecht.CrossRefGoogle Scholar
Neale, M. C. & Stevenson, J. (1989). Rater bias in the EASI temperament scales: a twin study. Journal of Personality and Social Psychology 56, 446455.CrossRefGoogle Scholar
Nichols, R. C. & Bilbro, W. C. (1966). The diagnosis of twin zygosity. Acta Genetica, Basel 16, 265275.Google ScholarPubMed
Paykel, E. S. (1978). Contribution of life events to causation of psychiatric illness. Psychological Medicine 8, 245253.CrossRefGoogle ScholarPubMed
Plomin, R. (1994). Genetics and Experience. The Interplay Between Nature and Nurture. Sage: Thousand Oaks.Google Scholar
Plomin, R. & Bergeman, C. S. (1991). The nature of nurture: genetic influence on ‘environmental’ measures. Behavioral and Brain Sciences 14, 373427.CrossRefGoogle Scholar
Plomin, R., Litchenstein, P., Pedersen, N. L., McClearn, G. E. & Nesselroade, J. R. (1990). Genetic influences on life events during the last half of the life span. Psychology and Aging 5, 2530.CrossRefGoogle ScholarPubMed
Poulton, R. G. & Andrews, G. (1992). Personality as a cause of adverse life events. Acta Psychiatrica Scandinavica 85, 3538.CrossRefGoogle ScholarPubMed
Scarr, S. & McCartney, K. (1983). How people make their own environments: a theory of genotype environment effects. Child Development 54, 424435.Google Scholar
Schulman, P., Keith, D. & Seligman, M. E. (1993). Is optimism heritable? A study of twins. Behaviour Research and Therapy 31, 569574.CrossRefGoogle ScholarPubMed
Simons, A. D., Angell, K. L., Monroe, S. M. & Thase, M. E. (1993). Cognition and life stress in depression cognitive factors and the definition, rating and generation of negative life events. Journal of Abnormal Psychology 102, 584591.CrossRefGoogle ScholarPubMed
Thapar, A. & McGuffin, P. (1994). A twin study of depressive symptoms in childhood. British Journal of Psychiatry 165, 259265.CrossRefGoogle ScholarPubMed
Thapar, A., Hervas, A. & McGuffin, P. (1995). Childhood hyperactivity disorder is highly heritable and shows sibling competition effects: twin study evidence. Behaviour Genetics 25, 537544.CrossRefGoogle ScholarPubMed