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Factors influencing the occurrence of schizophrenia-like psychosis in patients with temporal lobe epilepsy

Published online by Cambridge University Press:  09 July 2009

David C. Taylor
David C. Taylor
Affiliation:
Human Development Research Unit, Park Hospital for Children, Oxford
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Synopsis

From a series of 255 patients who had undergone temporal lobectomy for the relief of intractable psychomotor epilepsy, all 47 patients with ‘alien tissue’ (small tumours, hamartomas, focal dysplasia) in the resected temporal lobe were contrasted with a group of 41 patients who showed mesial temporal sclerosis in their resected lobe. Five per cent of the mesial temporal sclerosis group and 23% of the alien tissue group were psychotic. A marked interaction occurred between psychosis and ‘left handedness’. In the alien tissue group, females, especially left-handed females, were the most likely to have developed a schizophrenia-like psychosis.

Type
Original Article
Information
Psychological Medicine , Volume 5 , Issue 3 , August 1975 , pp. 249 - 254
Copyright
Copyright © Cambridge University Press 1975

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