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Facial emotion processing in schizophrenia: a non-specific neuropsychological deficit?

Published online by Cambridge University Press:  24 September 2009

E. Pomarol-Clotet ,
F. Hynes ,
C. Ashwin ,
E. T. Bullmore ,
P. J. McKenna  and
K. R. Laws
E. Pomarol-Clotet*
Affiliation:
Benito Menni Complex Assistencial Salut Mental, Barcelona, and CIBERSAM, Spain
F. Hynes
Affiliation:
Birmingham and Solihull Mental Health Trust, Birmingham, UK
C. Ashwin
Affiliation:
Department of Psychology, University of Bath, UK
E. T. Bullmore
Affiliation:
Department of Psychiatry, University of Cambridge, Addenbrooke's Hospital, UK
P. J. McKenna
Affiliation:
Benito Menni Complex Assistencial Salut Mental, Barcelona, and CIBERSAM, Spain
K. R. Laws
Affiliation:
School of Psychology, University of Hertfordshire, UK
*
*Address for correspondence: Dr E. Pomarol-Clotet, Benito Menni Complex Assistencial en Salut Mental, Germanes Hospitalàries del Sagrat Cor de Jesús, C/Doctor Antoni Pujades 38-C, 08830 Sant Boi de Llobregat, Barcelona, Spain. (Email: [email protected])
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Abstract

Background

Identification of facial emotions has been found to be impaired in schizophrenia but there are uncertainties about the neuropsychological specificity of the finding.

Method

Twenty-two patients with schizophrenia and 20 healthy controls were given tests requiring identification of facial emotion, judgement of the intensity of emotional expressions without identification, familiar face recognition and the Benton Facial Recognition Test (BFRT). The schizophrenia patients were selected to be relatively intellectually preserved.

Results

The patients with schizophrenia showed no deficit in identifying facial emotion, although they were slower than the controls. They were, however, impaired on judging the intensity of emotional expression without identification. They showed impairment in recognizing familiar faces but not on the BFRT.

Conclusions

When steps are taken to reduce the effects of general intellectual impairment, there is no deficit in identifying facial emotions in schizophrenia. There may, however, be a deficit in judging emotional intensity. The impairment found in naming familiar faces is consistent with other evidence of semantic memory impairment in the disorder.

Keywords

Cognitionemotionface processingschizophrenia
Type
Original Articles
Information
Psychological Medicine , Volume 40 , Issue 6 , June 2010 , pp. 911 - 919
Copyright
Copyright © Cambridge University Press 2009

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References

Archer, J, Hay, DC, Young, AW (1992). Face processing in psychiatric conditions. British Journal of Psychiatry 31, 45–61.Google ScholarPubMed
Archer, J, Hay, DC, Young, AW (1994). Movement, face processing and schizophrenia: evidence of a differential deficit in expression analysis. British Journal of Clinical Psychology 33, 517–528.CrossRefGoogle ScholarPubMed
Bediou, B, Asri, F, Brunelin, J, Krolak-Salmon, P, D'Amato, T, Saoud, M, Tazi, I (2007). Emotion recognition and genetic vulnerability to schizophrenia. British Journal of Psychiatry 191, 126–130.CrossRefGoogle ScholarPubMed
Bediou, B, Franck, N, Saoud, M, Baudouin, JY, Tiberghien, G, Dalery, J, d'Amato, T (2005 a). Effects of emotion and identity on facial affect processing in schizophrenia. Psychiatry Research 133, 149–157.CrossRefGoogle ScholarPubMed
Bediou, B, Krolak-Salmon, P, Saoud, M, Henaff, MA, Burt, M, Dalery, J, D'Amato, T (2005 b). Facial expression and sex recognition in schizophrenia and depression. Canadian Journal of Psychiatry 50, 525–533.CrossRefGoogle ScholarPubMed
Bellack, AS, Blanchard, JJ, Mueser, KT (1996). Cue availability and affect perception in schizophrenia. Schizophrenia Bulletin 22, 535–544.CrossRefGoogle ScholarPubMed
Benton, AL, Sivan, AB, Hamsher, KD (1994). Contributions to Neuropsychological Assessment: A Clinical Manual. Oxford University Press: Oxford.Google Scholar
Bernard, FA, Bullmore, ET, Graham, KS, Thompson, SA, Hodges, JR, Fletcher, PC (2004). The hippocampal region is involved in successful recognition of both remote and recent famous faces. Neuroimage 22, 1704–1714.CrossRefGoogle ScholarPubMed
Bigelow, NO, Paradiso, S, Adolphs, R, Moser, DJ, Arndt, S, Heberlein, A, Nopoulos, P, Andreasen, NC (2006). Perception of socially relevant stimuli in schizophrenia. Schizophrenia Research 83, 257–267.CrossRefGoogle ScholarPubMed
Brune, M (2005 a). Emotion recognition, ‘theory of mind,’ and social behavior in schizophrenia. Psychiatry Research 133, 135–147.CrossRefGoogle ScholarPubMed
Brune, M (2005 b). ‘Theory of mind’ in schizophrenia: a review of the literature. Schizophrenia Bulletin 31, 21–42.CrossRefGoogle ScholarPubMed
Calder, AJ, Young, AW (2005). Understanding the recognition of facial identity and facial expression. Nature Reviews. Neuroscience 6, 641–651.CrossRefGoogle ScholarPubMed
Chambon, V, Baudouin, JY, Frank, N (2006). The role of configural information in facial emotion recognition in schizophrenia. Neuropsychologia 44, 2437–2444.CrossRefGoogle ScholarPubMed
Chapman, LJ, Chapman, JP (1973). Disordered Thought in Schizophrenia. Appleton-Century-Crofts: New York.Google Scholar
Derntl, B, Finkelmeyer, A, Toygar, TK, Hulsmann, A, Schneider, F, Falkenberg, DI, Habel, U (2009). Generalized deficit in all core components of empathy in schizophrenia. Schizophrenia Research 108, 197–206.CrossRefGoogle ScholarPubMed
Edwards, J, Jackson, HJ, Pattison, PE (2002). Emotion recognition via facial expression and affective prosody in schizophrenia: a methodological review. Clinical Psychology Review 22, 789–832.CrossRefGoogle ScholarPubMed
Edwards, J, Pattison, PE, Jackson, HJ, Wales, RJ (2001). Facial affect and affective prosody recognition in first-episode schizophrenia. Schizophrenia Research 48, 235–253.CrossRefGoogle ScholarPubMed
Ekman, P, Friesen, W (1976). Pictures of Facial Affect. Consulting Psychologists Press: Palo Alto.Google Scholar
Ellis, AW, Young, AW (1988). Human Cognitive Neuropsychology. Erlbaum: Hove.Google Scholar
Endicott, J, Spitzer, RL, Fleiss, JL, Cohen, J (1976). The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance. Archives of General Psychiatry 33, 766–771.CrossRefGoogle Scholar
Gabrovska, VS, Laws, KR, Sinclair, J, McKenna, PJ (2003). Visual object processing in schizophrenia: evidence for an associative agnosic deficit. Schizophrenia Research 59, 277–286.CrossRefGoogle ScholarPubMed
Gaebel, W, Wolwer, W (1992). Facial expression and emotional face recognition in schizophrenia and depression. European Archives of Psychiatry and Clinical Neuroscience 242, 46–52.CrossRefGoogle ScholarPubMed
Gur, RE, McGrath, C, Chan, RM, Schroeder, L, Turner, T, Turetsky, BI, Kohler, C, Alsop, D, Maldjian, J, Ragland, JD, Gur, RC (2002). An fMRI study of facial emotion processing in patients with schizophrenia. American Journal of Psychiatry 159, 1992–1999.CrossRefGoogle ScholarPubMed
Hall, J, Whalley, HC, McKirdy, JW, Romaniuk, L, McGonigle, D, McIntosh, AM, Baig, BJ, Gounto una, VE, Job, DE, Donaldson, DI, Sprengelmeyer, R, Young, AW, Johnstone, EC, Lawrie, SM (2008). Overactivation of fear systems to neutral faces in schizophrenia. Biological Psychiatry 64, 70–73.CrossRefGoogle ScholarPubMed
Haxby, JV, Hoffman, EA, Gobbini, MI (2000). The distributed human neural system for face perception. Trends in Cognitive Sciences 4, 223–233.CrossRefGoogle ScholarPubMed
Hofer, A, Benecke, C, Edlinger, M, Huber, R, Kemmler, G, Rettenbacher, MA, Schleich, G, Fleischhacker, WW (2009). Facial emotion recognition and its relationship to symptomatic, subjective, and functional outcomes in outpatients with chronic schizophrenia. European Psychiatry 24, 27–32.CrossRefGoogle ScholarPubMed
Johnston, PJ, Enticott, PG, Mayes, AK, Hoy, KE, Herring, SE, Fitzgerald, PB (2008). Symptom correlates of static and dynamic facial affect processing in schizophrenia: evidence of a double dissociation? Schizophrenia Bulletin. Published online: 26 October 2008. doi:10.1093/schbul/sbn136.CrossRefGoogle Scholar
Johnston, PJ, Katsikitis, M, Carr, VJ (2001). A generalised deficit can account for problems in facial emotion recognition in schizophrenia. Biological Psychology 58, 203–227.CrossRefGoogle ScholarPubMed
Kerr, SL, Neale, JM (1993). Emotion perception in schizophrenia: specific deficit or further evidence of generalized poor performance? Journal of Abnormal Psychology 102, 312–318.CrossRefGoogle ScholarPubMed
Kohler, CG, Bilker, W, Hagendoorn, M, Gur, RE, Gur, RC (2000). Emotion recognition deficit in schizophrenia: association with symptomatology and cognition. Biological Psychiatry 48, 127–136.CrossRefGoogle ScholarPubMed
Kohler, CG, Turner, TH, Bilker, WB, Brensinger, CM, Siegel, SJ, Kanes, SJ, Gur, RE, Gur, RC (2003). Facial emotion recognition in schizophrenia: intensity effects and error pattern. American Journal of Psychiatry 160, 1768–1774.CrossRefGoogle ScholarPubMed
Kohler, CG, Walker, JB, Martin, EA, Healey, KM, Moberg, PJ (2009). Facial emotion perception in schizophrenia: a meta-analytic review. Schizophrenia Bulletin. Published online: 27 March 2009. doi:10.1093/schbul/sbn192.Google ScholarPubMed
Kucharska-Pietura, K, David, AS, Masiak, M, Phillips, ML (2005). Perception of facial and vocal affect by people with schizophrenia in early and late stages of illness. British Journal of Psychiatry 187, 523–528.CrossRefGoogle ScholarPubMed
Laws, K, McKenna, PJ, McCarthy, RA (1996). Reconsidering the gospel according to group studies: a neuropsychological case study approach to schizophrenia. Cognitive Neuropsychiatry 1, 319–343.CrossRefGoogle ScholarPubMed
Mandal, MK, Pandey, R, Prasad, AB (1998). Facial expressions of emotions and schizophrenia: a review. Schizophrenia Bulletin 24, 399–412.CrossRefGoogle ScholarPubMed
Marwick, K, Hall, J (2008). Social cognition in schizophrenia: a review of face processing. British Medical Bulletin 88, 43–58.CrossRefGoogle ScholarPubMed
McKenna, PJ (2007). Schizophrenia and Related Syndromes, 2nd edn. Routledge: Hove.Google Scholar
McKenna, PJ, Ornstein, T, Baddeley, AD (2002). Schizophrenia. In Handbook of Memory Disorders (ed. Baddeley, A. D., Wilson, B. A. and Kopelman, M.), pp. 413–435. Wiley: Chichester.Google Scholar
Namiki, C, Hirao, K, Yamada, M, Hanakawa, T, Fukuyama, H, Hayashi, T, Murai, T (2007). Impaired facial emotion recognition and reduced amygdalar volume in schizophrenia. Psychiatry Research 156, 23–32.CrossRefGoogle ScholarPubMed
Nelson, HE, Willison, JR (1991). The Revised National Adult Reading Test: Test Manual. NFER-Nelson: Windsor, Berks.Google Scholar
Novic, J, Luchins, DJ, Perline, R (1984). Facial affect recognition in schizophrenia. Is there a differential deficit? British Journal of Psychiatry 144, 533–537.CrossRefGoogle Scholar
Phillips, ML, Williams, L, Senior, C, Bullmore, ET, Brammer, MJ, Andrew, C, Williams, SC, David, AS (1999). A differential neural response to threatening and non-threatening negative facial expressions in paranoid and non-paranoid schizophrenics. Psychiatry Research 92, 11–31.CrossRefGoogle ScholarPubMed
Pinkham, AE, Penn, DL, Perkins, DO, Lieberman, J (2003). Implications for the neural basis of social cognition for the study of schizophrenia. American Journal of Psychiatry 160, 815–824.CrossRefGoogle Scholar
Reichenberg, A, Harvey, PD (2007). Neuropsychological impairments in schizophrenia: integration of performance-based and brain imaging findings. Psychological Bulletin 133, 833–858.CrossRefGoogle ScholarPubMed
Reske, M, Habel, U, Kellermann, T, Backes, V, Jon Shah, N, von Wilmsdorff, M, Gaebel, W, Zilles, K, Schneider, F (2009). Differential brain activation during facial emotion discrimination in first-episode schizophrenia. Journal of Psychiatric Research 43, 592–599.CrossRefGoogle ScholarPubMed
Sachs, G, Steger-Wuchse, D, Kryspin-Exner, I, Gur, RC, Katschnig, H (2004). Facial recognition deficits and cognition in schizophrenia. Schizophrenia Research 68, 27–35.CrossRefGoogle ScholarPubMed
Salem, JE, Kring, AM, Kerr, SL (1996). More evidence for generalized poor performance in facial emotion perception in schizophrenia. Journal of Abnormal Psychology 105, 480–483.CrossRefGoogle ScholarPubMed
Schatz, J (1998). Cognitive processing efficiency in schizophrenia: generalized vs domain specific deficits. Schizophrenia Research 30, 41–49.CrossRefGoogle ScholarPubMed
Schneider, F, Gur, RC, Gur, RE, Shtasel, DL (1995). Emotional processing in schizophrenia: neurobehavioral probes in relation to psychopathology. Schizophrenia Research 17, 67–75.CrossRefGoogle ScholarPubMed
Schneider, F, Gur, RC, Koch, K, Backes, V, Amunts, K, Shah, NJ, Bilker, W, Gur, RE, Habel, U (2006). Impairment in the specificity of emotion processing in schizophrenia. American Journal of Psychiatry 163, 442–447.CrossRefGoogle ScholarPubMed
Silver, H, Shlomo, N, Turner, T, Gur, RC (2002). Perception of happy and sad facial expressions in chronic schizophrenia: evidence for two evaluative systems. Schizophrenia Research 55, 171–177.CrossRefGoogle ScholarPubMed
Sprong, M, Schothorst, P, Vos, E, Hox, J, van Engeland, H (2007). Theory of mind in schizophrenia: meta-analysis. British Journal of Psychiatry 191, 5–13.CrossRefGoogle ScholarPubMed
Tsoi, DT, Lee, KH, Khokhar, WA, Mir, NU, Swalli, JS, Gee, KA, Pluck, G, Woodruff, PW (2008). Is facial emotion recognition impairment in schizophrenia identical for different emotions? A signal detection analysis. Schizophrenia Research 99, 263–269.CrossRefGoogle ScholarPubMed
Turetsky, BI, Kohler, CG, Indersmitten, T, Bhati, MT, Charbonnier, D, Gur, RC (2007). Facial emotion recognition in schizophrenia: when and why does it go awry? Schizophrenia Research 94, 253–263.CrossRefGoogle ScholarPubMed
Van't Wout, M, van Dijke, A, Aleman, A, Kessels, RP, Pijpers, W, Kahn, RS (2007). Fearful faces in schizophrenia: the relationship between patient characteristics and facial affect recognition. Journal of Nervous and Mental Disease 195, 758–764.CrossRefGoogle ScholarPubMed
Walker, E, McGuire, M, Bettes, B (1984). Recognition and identification of facial stimuli by schizophrenics and patients with affective disorders. British Journal of Clinical Psychology 23, 37–44.CrossRefGoogle ScholarPubMed
Wing, JK, Cooper, JE, Sartorius, N (1974). The Measurement and Classification of Psychiatric Symptoms. Cambridge University Press: Cambridge.Google Scholar
Wynn, JK, Lee, J, Horan, WP, Green, MF (2008). Using event related potentials to explore stages of facial affect recognition deficits in schizophrenia. Schizophrenia Bulletin 34, 679–687.CrossRefGoogle ScholarPubMed