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Duration of relapse prevention after cognitive therapy in residual depression: follow-up of controlled trial

Published online by Cambridge University Press:  21 December 2004

E. S. PAYKEL ,
J. SCOTT ,
P. L. CORNWALL ,
R. ABBOTT ,
C. CRANE ,
M. POPE  and
A. L. JOHNSON
E. S. PAYKEL
Affiliation:
Department of Psychiatry, University of Cambridge, UK; Department of Psychiatry, University of Newcastle, UK; the Institute of Psychiatry, London, UK; MRC Biostatistics Unit, Cambridge, UK
J. SCOTT
Affiliation:
Department of Psychiatry, University of Cambridge, UK; Department of Psychiatry, University of Newcastle, UK; the Institute of Psychiatry, London, UK; MRC Biostatistics Unit, Cambridge, UK
P. L. CORNWALL
Affiliation:
Department of Psychiatry, University of Cambridge, UK; Department of Psychiatry, University of Newcastle, UK; the Institute of Psychiatry, London, UK; MRC Biostatistics Unit, Cambridge, UK
R. ABBOTT
Affiliation:
Department of Psychiatry, University of Cambridge, UK; Department of Psychiatry, University of Newcastle, UK; the Institute of Psychiatry, London, UK; MRC Biostatistics Unit, Cambridge, UK
C. CRANE
Affiliation:
Department of Psychiatry, University of Cambridge, UK; Department of Psychiatry, University of Newcastle, UK; the Institute of Psychiatry, London, UK; MRC Biostatistics Unit, Cambridge, UK
M. POPE
Affiliation:
Department of Psychiatry, University of Cambridge, UK; Department of Psychiatry, University of Newcastle, UK; the Institute of Psychiatry, London, UK; MRC Biostatistics Unit, Cambridge, UK
A. L. JOHNSON
Affiliation:
Department of Psychiatry, University of Cambridge, UK; Department of Psychiatry, University of Newcastle, UK; the Institute of Psychiatry, London, UK; MRC Biostatistics Unit, Cambridge, UK
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Abstract

Background. Although there is good evidence that cognitive therapy (CBT) lessens relapse and recurrence in unipolar depression, the duration of this effect is not known.

Method. One hundred and fifty-eight subjects, from a randomized controlled trial of CBT plus medication and clinical management versus medication and clinical management alone, were followed 6 years after randomization (4½ years after completion of CBT) and the longitudinal course assessed.

Results. Effects in prevention of relapse and recurrence were found to persist, with weakening, and were not fully lost until 3½ years after the end of CBT. Residual symptoms were also lessened.

Conclusions. The effect of CBT in reduction of relapse and recurrence persists for several years. The potential value of subsequent additional CBT some time after cessation should be explored.

Type
Research Article
Information
Psychological Medicine , Volume 35 , Issue 1 , January 2005 , pp. 59 - 68
Copyright
2005 Cambridge University Press

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