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Detecting psychiatric disorders in medical practice using the General Health Questionnaire. Why do cut-off scores vary?

Published online by Cambridge University Press:  09 July 2009

A. M. Van Hemert*
Affiliation:
Departments of Psychiatry and Internal Medicine, University Hospital, Leiden; Department of Psychiatry, Dijkzigt University Hospital, Rotterdam, The Netherlands
M. Den Heijer
Affiliation:
Departments of Psychiatry and Internal Medicine, University Hospital, Leiden; Department of Psychiatry, Dijkzigt University Hospital, Rotterdam, The Netherlands
M. Vorstenbosch
Affiliation:
Departments of Psychiatry and Internal Medicine, University Hospital, Leiden; Department of Psychiatry, Dijkzigt University Hospital, Rotterdam, The Netherlands
J. H. Bolk
Affiliation:
Departments of Psychiatry and Internal Medicine, University Hospital, Leiden; Department of Psychiatry, Dijkzigt University Hospital, Rotterdam, The Netherlands
*
1Address for correspondence: Dr Albert M. van Hemert, Department of Psychiatry, Out-patient Clinic, University Hospital Leiden, Building 1, B1-P, PO Box 9600, 2300 RC Leiden, The Netherlands.

Synopsis

In this study we assessed the accuracy of the General Health Questionnaire in detecting psychiatric disorders in general medical out-patients. A total of 290 newly referred patients were interviewed with the Present State Examination. Prior to the interview, 112 patients completed the full GHQ-60, 100 completed the GHQ-30 and 78 completed the GHQ-12. Data from the first group were used to study the full GHQ-60, together with the GHQ-30 and and GHQ-12, when disembedded from the full questionnaire. In a comparison between the disembedded and the separate versions of the GHQ-30 and GHQ-12 we observed considerable variation in the cut-off scores where a certain sensitivity and specificity was attained. In ROC-analysis, the versions were not materially different in their discriminatory capacity (area under the curve). The use of different criteria to define a ‘case’ demonstrated that case severity was another source of increasing cut-off scores. Our data demonstrate that the use of disembedded or separate versions of the questionnaire, together with variation in the case criteria can be a major explanation for variation in cut-off scores that was observed in previous studies.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1995

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References

Cleary, P. D., Bush, B. T. & Kessler, L. G. (1987). Evaluating the use of mental health screening scales in primary care settings using receiver operating characteristics curves. Medical Care 25 (Suppl), S90S98.CrossRefGoogle Scholar
Garyfallos, G., Karastergiou, A., Adamopoulou, A., Moutzoukis, C., Alagiozidou, E., Mala, D. & Garyfallos, A. (1991). Greek version of the general health questionnaire: accuracy of translation and validity. Acta Psychiatrica Scandinavica 84, 371378.CrossRefGoogle ScholarPubMed
Goldberg, D. (1972). The Detection of Psychiatric Illness by Questionnaire. Oxford University Press: London.Google Scholar
Goldberg, D. (1985). Identifying psychiatric illness among general medical patients. British Medical Journal 291, 161162.CrossRefGoogle ScholarPubMed
Goldberg, D. (1986). Use of the general health questionnaire in clinical work. British Medical Journal 293, 11881189.CrossRefGoogle ScholarPubMed
Goldberg, D. & Hiller, V. F. (1979). A scaled version of the General Health Questionnaire. Psychological Medicine 9, 139145.CrossRefGoogle ScholarPubMed
Huppert, F. A., Walters, D. E., Day, N. E. & Elliot, B. J. (1989). The factor structure of the general health questionnaire (GHQ-30). A reliability study on 6317 community residents. British Journal of Psychiatry 155, 178185.CrossRefGoogle Scholar
Koeter, M. W. J. & Ormel, J. (1991). General Health Questionnaire. Nederlandse bewerking (Dutch version). Swets and Seitlinger B.V.: Lisse.Google Scholar
Mari, J. J. & Williams, P. (1985). A comparison of the validity of two psychiatric screening questionnaires (GHQ-12 and SRQ-20) in Brazil, using relative operating characteristic (ROC) analysis. Psychological Medicine 15, 651659.CrossRefGoogle ScholarPubMed
Mayou, R. & Hawton, K. (1986). Psychiatric disorders in General Hospital. British Journal of Psychiatry 149, 172190.CrossRefGoogle ScholarPubMed
Metz, C. E., Wang, P. L. & Heineman, H. B. (1984). ROCFIT. Department of Radiology & the Franklin McLean Memorial Research Institute. University of Chicago: Chicago.Google Scholar
Pan, P. C. & Goldberg, D. (1990). A comparison of the validity of GHQ-12 and CHQ-12 in Chinese primary care patients in Manchester. Psychological Medicine 20, 931940.CrossRefGoogle ScholarPubMed
Sacket, D. L., Haynes, R. B. & Tugwell, P. (1985). Clinical Epidemiology. A Basic Science for Clinical Medicine, pp. 59138. Little, Brown and Company: Boston/Toronto.Google Scholar
Slooff, C. J., Mulder-Hajonides van der Meulen, W. R. E. H. & Van den Hoofdakker, R. H. (1983). De nederlandse vertaling van de Present State Examination 9e editie. I. Betrouwbaarheidsaspecten. (The Dutch translation of the Present State Examination 9th edition. I. Aspects of reliability). Tijdschrift voor Psychiatrie 25, 151163.Google Scholar
Van Hemert, A. M., Hengeveld, M. W., Bolk, J. H., Rooijmans, H. G. M. & Vandenbroucke, J. P. (1993 a). Psychiatric disorders in relation to medical illness among patients of a general medical outpatient clinic. Psychological Medicine 23, 167173.CrossRefGoogle Scholar
Van Hemert, A. M., Hawton, K. E., Bolk, J. H. & Fagg, J. (1993 b). Key symptoms in the detection of affective disorders in general medical patients. Journal of Psychosomatic Research 37, 397404.CrossRefGoogle Scholar
Vásquez-Barquero, J. L., Williams, P., Diez-Manrique, J. F., Lequerica, J. & Arenal, A. (1988). The factor structure of the GHQ-60 in a community sample. Psychological Medicine 18, 211218.CrossRefGoogle Scholar
Wing, J. K. (1976). A technique for studying psychiatric morbidity in in-patient and out-patient series and in general population samples. Psychological Medicine 6, 665671.CrossRefGoogle ScholarPubMed
Wing, J. K., Cooper, J. & Sartorius, N. (1974). The Measurement and Classification of Psychiatric Symptoms. Cambridge University Press: Cambridge.Google Scholar