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Cognitive impairment and dementia in Parkinson's disease: a controlled study

Published online by Cambridge University Press:  09 July 2009

J. L. Boyd ,
C. A. Cruickshank ,
C. W. Kenn ,
P. Madeley ,
R. H. S. Mindham ,
A. G. Oswald ,
R. J. Smith  and
E. G. S. Spokes
J. L. Boyd*
Affiliation:
Department of Psychiatry, University of Leeds
C. A. Cruickshank
Affiliation:
Department of Psychiatry, University of Leeds
C. W. Kenn
Affiliation:
Department of Psychiatry, University of Leeds
P. Madeley
Affiliation:
Department of Psychiatry, University of Leeds
R. H. S. Mindham
Affiliation:
Department of Psychiatry, University of Leeds
A. G. Oswald
Affiliation:
Department of Psychiatry, University of Leeds
R. J. Smith
Affiliation:
Department of Psychiatry, University of Leeds
E. G. S. Spokes
Affiliation:
Department of Psychiatry, University of Leeds
*
1Address for correspondence: Mrs J. L. Boyd, Department of Psychiatry, 15 Hyde Terrace, Leeds LS2 9LT.
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Synopsis

The performance of 47 patients with Parkinson's disease on a battery of tests of cognition, motor function, disability and mood was compared with the performance of 47 healthy control subjects who were matched to the patients on the basis of age, sex and pre-morbid IQ. An increased prevalence of impairment over a range of cognitive functions was observed in the Parkinson's disease patients as compared with their matched controls. The differences between the Parkinson's disease patients and controls could not be accounted for by factors such as depressed mood, effects of medication or motor impairment. Our findings are discussed in relation to the methodology of previous studies in this area and to the need for a comprehensive clinico-pathological longitudinal study.

Type
Original Articles
Information
Psychological Medicine , Volume 21 , Issue 4 , November 1991 , pp. 911 - 921
Copyright
Copyright © Cambridge University Press 1991

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