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The case for biology in the aetiology of anorexia nervosa1

Published online by Cambridge University Press:  09 July 2009

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Copyright © Cambridge University Press 1994

References

Anand, B. K. & Brobeck, J. R. (1951). Localisation of a ‘feeding center’ in hypothalamus of the rat. Proceedings of the Society for Experimental Biology and Medicine 77, 323324.CrossRefGoogle ScholarPubMed
Beumont, P. J. V., Abrahams, S. F. & Simson, K. G. (1981). The psychosexual histories of adolescent girls and young women with anorexia nervosa. Psychological Medicine 11, 131140.CrossRefGoogle Scholar
Blundell, J. E. & Hill, A. J. (1991). Serotonin, eating disorders and the satiety cascade. In Serotonin-related Psychiatric Syndromes: Clinical and Therapeutic Links (ed. Cassano, C. B. and Akiskal, H. S.), pp. 125129. Royal Society of Medicine, Services International Congress and Symposium. Series No: 165.Google Scholar
Brewerton, T. D., Mueller, E. A., Brandt, H. A., Lesem, D., Murphy, D. L. & Jimerson, D. C. (1990). Serotonin in eating disorders. In Serotonin in Major Psychiatric Disorders (ed. Coccaro, E. F. and Murphy, D. L.), pp. 155184. American Journal of Psychiatry Press: Washington, DC.Google Scholar
Broberg, D. J. & Bernstein, I. L. (1989). Cephalic insulin release in anorexic women. Physiology and Behavior 45, 871874.CrossRefGoogle ScholarPubMed
Bryant-Waugh, R. & Lask, B. (1991). Anorexia nervosa in a group of Asian children living in Britain. British Journal of Psychiatry 158, 229233.CrossRefGoogle Scholar
Buchan, T. & Gregory, L. D. (1984). Anorexia nervosa in a black Zimbabwean. British Journal of Psychiatry 145, 326330.CrossRefGoogle Scholar
Buhrich, N. (1981). Frequency of presentation of anorexia nervosa in Malaysia. Australian and New Zealand Journal of Psychiatry 15, 153155.CrossRefGoogle ScholarPubMed
Buvat-Herbaut, M., Hebbinchuys, P., Lemaire, A. & Buvat, J. (1983). Attitudes towards weight, body image, eating, menstruation, pregnancy and sexuality in 81 cases of anorexia nervosa compared to 281 normal control school girls. International Journal of Eating Disorders 2, 4559.3.0.CO;2-1>CrossRefGoogle Scholar
Carter, A. & Davis, S. T. (1977). Biogenic amines, reproductive hormones and female sexual behaviour. A review. Behavioural Research 1: 213225.Google Scholar
Casper, R. C. (1990). Personality features of women with good outcome from restricting anorexia nervosa. Psychosomatic Medicine 52, 156170.CrossRefGoogle ScholarPubMed
Casper, R. C., Pandy, G. N., Jaspan, J. B. & Rubenstein, A. H. (1988). Hormone and metabolite plasma levels after oral glucose in bulimia and healthy controls. Biological Psychiatry 24, 663674.CrossRefGoogle ScholarPubMed
Chernin, K. (1986). The Hungry Self. Virago: London.Google Scholar
Cloninger, C. R. (1987). A systematic model for clinical description and classification of personality variants: a proposal. Archives of General Psychiatry 44, 573588.CrossRefGoogle Scholar
Coddington, R. D. & Bruch, H. (1970). Gastric perceptivity in normal, obese and schizophrenic subjects. Psychosomatics 11, 571579.CrossRefGoogle ScholarPubMed
Coppen, A. J., Gupta, R. K., Eccleston, E. G., Wood, K. M. & Wakeling, A. (1976). Plasma tryptophan in anorexia nervosa. Lancet i, 961.CrossRefGoogle Scholar
Crisp, A. H. (1967). The possible significance of some behavioural correlates of weight and carbohydrate intake. Journal of Psychosomatic Research 11, 117131.CrossRefGoogle ScholarPubMed
Curzon, G. (1992). Serotonin and eating disorders: pharmacological relationships. International Academy of Biomedical Drug Research 1, 112128.Google Scholar
Donohoe, T. P. (1984). Stress-induced anorexia: implications for anorexia nervosa. Life Sciences 34, 203218.CrossRefGoogle ScholarPubMed
Dourish, C. T., Kennett, G. A. & Curzon, G. (1987). The 5-HT-1A agonists 8-OH-DPAT, buspirone and ipsapirone attenuate stress-induced anorexia in rats. Journal of Psychopharmacology 1, 2331.CrossRefGoogle ScholarPubMed
Dunn, A. J. & Welch, J. (1991). Stress and endotoxin-induced increases in brain tryptophan and serotonin metabolism depend on sympathetic nervous system activation. Journal of Neurochemistry 57, 16151622.CrossRefGoogle Scholar
Edwards, G. (1987). Anorexia and the family. In Fed Up and Hungry: Women, Oppression and Food (ed. Lawrence, M.), pp. 3341. Women's Press: London.Google Scholar
Escamilla, R. F. & Lisser, H. (1942). ‘Simmond's disease’. Journal of Clinical Endocrinology 2, 65.CrossRefGoogle Scholar
Fairburn, C. G. (1983). Eating disorders. In Companion to Psychiatric Studies (ed. Kendell, R. E. and Zealley, A. K.), pp. 535547. Churchill Livingstone: Edinburgh.Google Scholar
Frankfurt, M. & McEwen, B. S. (1991). 5, 7-Dihydroxytryptamine and gonadal steroid manipulation alter spine density in ventromedial hypothalamic neurons. Neuroendocrinology 54, 654657.CrossRefGoogle ScholarPubMed
Gandhi, D. H., Prakash Appaya, M. & Machado, T. (1991). Anorexia nervosa in Asian children. British Journal of Psychiatry 159, 591592.CrossRefGoogle ScholarPubMed
Goodall, E. & Silverstone, T. (1988). Differential effect of D-fenfluramine and metergoline on food intake in human subjects. Appetite 11, 215228.CrossRefGoogle ScholarPubMed
Goodwin, G. M., Fairburn, C. G. & Cowen, P. J. (1987). The effects of dieting and weight loss on neuroendocrine responses to tryptophan, clonidine and apomorphine in volunteers. Archives of General Psychiatry 44, 952955.CrossRefGoogle ScholarPubMed
Goodwin, G. M., Shapiro, C. M., Bennie, J., Dick, H., Carroll, S. & Fink, G. (1989). The neuroendocrine responses and psychological effects of infusion of L-tryptophan in anorexia nervosa. Psychological Medicine 19, 857864.CrossRefGoogle ScholarPubMed
Gull, W. W. (1873). Proceedings of the Clinical Society of London. British Medical Journal i, 527529.Google Scholar
Haleem, D. J. (1988). Serotoninergic functions in rat brain: sex-related differences and responses to stress. Ph.D. thesis, University of London.Google Scholar
Haleem, D. J., Kennett, G. A. & Curzon, G. (1988). Adaptation of female rats to stress: shift to male pattern by inhibition of corticosterone synthesis. Brain Research 458, 339347.CrossRefGoogle ScholarPubMed
Hetherington, M. M. & Rolls, B. J. (1988). Sensory-specific satiety and food intake in eating disorders. In Eating Behaviour in Eating Disorders (ed. Walsh, B. T.), pp. 141160. American Psychiatric Press: Washington, DC.Google Scholar
Hetherington, M. M. & Rolls, B. J. (1991). Eating behaviour in eating disorders: response to preloads. Physiology and Behaviour 50, 101108.CrossRefGoogle ScholarPubMed
Hill, A. J. & Blundell, J. E. (1990). Sensitivity of the appetite control system in obese subjects to nutritional and serotoninergic challenges. International Journal of Obesity 14, 219233.Google ScholarPubMed
Hill, A. J. & Blundell, J. E. (1991). Food selection, body weight and the premenstrual syndrome (PMS). Effect of D-fenfluramine. (Abstr.) International Journal of Obesity 15, 215.Google Scholar
Holden, N. L. & Robinson, P. H. (1988). Anorexia nervosa and bulimia nervosa in British blacks. British Journal of Psychiatry 152, 544549.CrossRefGoogle ScholarPubMed
Holland, A. J., Hall, A., Murray, R., Russell, G. F. M. & Crisp, A. (1984). Anorexia nervosa: a study of 34 twin pairs and one set of triplets. British Journal of Psychiatry 145, 414419.CrossRefGoogle ScholarPubMed
Holland, A. J., Sicotte, N. & Treasure, J. L. (1988). Anorexia nervosa: evidence for a genetic basis. Journal of Psychosomatic Research 32, 561571.CrossRefGoogle ScholarPubMed
Humphrey, L. L., Apple, R. F. & Kirschenbaum, D. S. (1986). Differentiating bulimic-anorexic from normal families using interpersonal and behavioural observational systems. Journal of Consulting and Clinical Psychology 54, 190195.CrossRefGoogle ScholarPubMed
Irvin, L. (1983). Castaway. Penguin: London.Google Scholar
Janet, P. (1907). The Major Symptoms of Hysteria. Macmillan: London.CrossRefGoogle Scholar
Johnston, J. L., Leiter, L. A., Burrow, G. N., Garfinkel, P. E. & Anderson, G. H. (1984). Excretion of urinary catecholamine metabolites in anorexia nervosa: effect of body composition and energy intake. American Journal of Clinical Nutrition 40, 10011006.CrossRefGoogle ScholarPubMed
Jones, D. J., Fox, M. M., Babigan, H. M. & Hutton, H. E. (1980). Epidemiology of anorexia nervosa in Munroe County, New York: 1960–1976. Psychosomatic Medicine 42, 551558.CrossRefGoogle Scholar
Kalan, P., Rosegren, E., Lindvall, O. & Bjorklund, A. (1989). Hippocampal noradrenaline and serotonin release over 24 hours as measured by the dialysis technique in freely moving rats: correlation to behavioural activity state, effect of handling and tail pinch. European Journal of Neuroscience 1, 181188.CrossRefGoogle Scholar
Kaye, W. H., Gwirtsman, H. E., Brewerton, T. D., George, D. T. & Wurtman, R. J. (1988 a). Bingeing behavior and plasma amino acids: a possible involvement of brain serotonin in bulimia nervosa. Psychiatry Research 23, 3143.CrossRefGoogle ScholarPubMed
Kaye, W. H., Gwirstman, H. E., George, D. T., Jimerson, D. C. & Ebert, M. H. (1988 b). CSF 5-HIAA concentrations in anorexia nervosa: reduced values in underweight subjects normalise after weight gain. Biological Psychiatry 23, 102105.CrossRefGoogle ScholarPubMed
Kaye, W. H., Ballenger, J. C., Lydiard, R. B., Stuart, G. W., Laraia, M. T., O'Neil, P., Fossey, M. D., Stevens, V., Lesser, S. & Hsu, G. (1990 a). CFS monoamine levels in normal-weight bulimia: evidence for abnormal noradrenergic activity. American Journal of Psychiatry 147, 225229.Google Scholar
Kaye, W. H., Berrettini, W., Gwirtsman, H. & George, D. T. (1990 b). Altered cerebrospinal fluid neuropeptide Y and peptide YY immunoreactivity in anorexia and bulimia nervosa. Archives of General Psychiatry 47, 548556.CrossRefGoogle ScholarPubMed
Kaye, W. H., Gwirstman, H. E., George, D. T. & Ebert, M. H. (1991). Altered serotonin activity in anorexia nervosa after long-term weight restoration. Archives of General Psychiatry 48, 556562.CrossRefGoogle ScholarPubMed
Kendell, R. E., Hall, D. J. & Hailey, A. (1973). The epidemiology of anorexia nervosa. Psychological Medicine 3, 200203.CrossRefGoogle ScholarPubMed
Kennett, G. A., Chaouloff, F., Marcou, M. & Curzon, G. (1986). Female rats are more vulnerable than males in an animal model of depression: the possible role of serotonin. Brain Research 382, 416421.CrossRefGoogle Scholar
Kennett, G. A., Dourish, C. T. & Curzon, G. (1987 a). 5-HT (1B) agonists induce anorexia at a post-synaptic site, 5-HT (1A) agonists cause hyperphagia. European Journal of Pharmacology 141, 429435.CrossRefGoogle Scholar
Kennett, G. A., Dourish, C. T. & Curzon, G. (1987 b). Antidepressant-like action of 5-HT-1A agonists and conventional antidepressants in an animal model of depression. European Journal of Pharmacology 134, 265274.CrossRefGoogle Scholar
Keys, A., Brozak, J., Henshall, A., Mickelson, O. & Taylor, H. L. (1950). The Biology of Human Starvation, Vol II, pp. 850857. University of Minnesota Press: Minneapolis.CrossRefGoogle Scholar
Khandelwal, S. K. & Sazena, S. (1990). Anorexia nervosa in people of Asian extraction. British Journal of Psychiatry 157, 784.CrossRefGoogle Scholar
Kog, E. & Vandereycken, W. (1989). Family interaction in eating disorder patients and normal controls. International Journal of Eating Disorders 8, 1123.3.0.CO;2-1>CrossRefGoogle Scholar
Kope, T. M. & Sack, W. H. (1987). Anorexia nervosa in Southeast Asian refugees: a report on three cases. Journal of the American Academy of Child and Adolescent Psychiatry 26, 795796.CrossRefGoogle ScholarPubMed
Lasègue, E. C. (1873). On hysterical anorexia. Medical Times Gazette 2, 265269.Google Scholar
Lee, S. (1991). Anorexia nervosa in Hong Kong: a Chinese perspective. Psychological Medicine 21, 703712.CrossRefGoogle Scholar
Leiter, L. A., Huboticky, N. & Anderson, G. H. (1987). Effects of L-tryptophan on food intake and selection in lean men and women. Annals of the New York Academy of Sciences 499, 327328.CrossRefGoogle Scholar
Linniola, M., Virkkunen, M., Scheinin, M., Nuutila, A., Rimon, R. & Goodwin, F. K. (1983). Low cerebrospinal fluid 5-HIAA concentration differentiates impulsive from non-impulsive violent behaviour. Life Sciences 33, 26092614.CrossRefGoogle Scholar
Littlewood, R. (1992). DSM-IV and culture: is the classification internationally valid? Psychiatric Bulletin 16, 257261.CrossRefGoogle Scholar
Lucas, A. R., Beard, C. M., O'Fallon, W. M. & Kurland, L. T. (1988). Anorexia nervosa in Rochester, Minnesota: a 45-year study. Mayo Clinic Proceedings 63, 433442.CrossRefGoogle ScholarPubMed
Lucas, A. R., Beard, M. C., O'Fallon, M. W. & Kurland, L. T. (1991). 50-year trends in the incidence of anorexia nervosa in Rochester, Minn.: a population-based study. American Journal of Psychiatry 148, 917922.Google ScholarPubMed
Luine, V. N., Frankfurt, M., Rainbow, T. C., Biegon, A. & Asmitia, E. (1983). Intrahypothalamic 5,7-dihydroxytryptamine facilitates feminine sexual behaviour and decreases (H)imipramine binding and 5-HT uptake. Brain Research 264, 344348.CrossRefGoogle Scholar
Luine, V. N., Thornton, J. E., Frankfurt, M. & MacLusky, N. J. (1987). Effects of hypothalamic serotonin depletion on lordosis behaviour and gonadal hormone receptors. Brain Research 426, 4754.CrossRefGoogle ScholarPubMed
McBride, P. A., Anderson, G. M., Khait, V. D., Sunday, S. R. & Halmi, K. A. (1991). Serotoninergic responsivity in eating disorders. Psychopharmacology Bulletin 27, 365372.Google Scholar
McCullagh, E. P. & Tupper, W. R. (1940). ‘Anorexia Nervosa’. Annals of International Medicine 14, 817821.Google Scholar
Marcé, L. A. (1860). On a form of hypochondriacal delirium occurring consecutive to dyspepsia and characterized by refusal of food. Journal of Psychological Medicine and Mental Pathology 13, 204206.Google Scholar
Meyer, J. E. (1961). Das Syndrom der Anorexia Nervosa: Katamnestische Untersuchungen. Archiv für Pschychiatrie und Nervenkrankheiten und Zeitschrift für die Gesämte Neurologie und Psychiatrie 202, 3159.CrossRefGoogle Scholar
Morley, J. E. & Blundell, J. E. (1988). The neurobiological basis of eating disorders: some formulations. Biological Psychiatry 23, 5378.CrossRefGoogle ScholarPubMed
Morley, J. E., Levine, A. D. & Willenberg, M. L. (1986). Stress-induced feeding disorders. In Pharmacology of Eating Disorders: Theoretical and Clinical Developments (ed. Carruba, M. A. and Blundell, J. E.), pp. 7199. Raven Press: New York.Google Scholar
Morton, R. (1694). Phthisiologia – Or a Treatise of Consumptions. Smith & Walford: London.Google Scholar
Mumford, D. B., Whitehouse, A. M. & Platts, M. (1991). Eating disorders among Asian schoolgirls in Bradford: socio-cultural correlates. British Journal of Psychiatry 158, 222228.CrossRefGoogle Scholar
Norman, R. L. & Smith, C. J. (1991). Restraint inhibits luteinizing hormone and testosterone secretion in intact male rhesus macaques: effects of concurrent naloxone administration. Neuroendocrinology 55, 405415.CrossRefGoogle Scholar
Nwaefuna, A. (1981). Anorexia nervosa in a developing country. British Journal of Psychiatry 138, 270271.CrossRefGoogle ScholarPubMed
O'Dwyer, A. & Treasure, J. (1992). Assessment of the tridimensional personality questionnaire in eating disorders: is it a useful investigative tool?Presentation at Royal College of Psychiatrists Annual Meeting,Dublin.Google Scholar
O'Keane, V. & Dinan, T. G. (1991). Prolactin and cortisol responses to D-fenfluramine in major depression: evidence for diminished responsivity of central serotoninergic function. American Journal of Psychiatry 148, 10091015.Google Scholar
O'Keane, V., O'Hanlon, M. & Webb, M. (1991). Prolactin responses throughout the menstrual cycle: evidence for an oestrogen-induced alteration. Clinical Endocrinology 34, 289292.CrossRefGoogle ScholarPubMed
O'Keane, V., Moloney, E., O'Neill, H., O'Connor, A., Smith, C. & Dinan, T. G. (1992). Blunted prolactin responses to D-fenfluramine in sociopathy. Evidence for sub-sensitivity of central serotoninergic function. British Journal of Psychiatry 160, 643646.CrossRefGoogle Scholar
Ong, Y. L., Tsoi, W. F. & Cheah, J. S. (1982). A clinical and psychosocial study of seven cases of anorexia nervosa in Singapore. Singapore Medical Journal 23, 255261.Google ScholarPubMed
Orbach, S. (1986). Hunger Strike. Penguin: London.Google Scholar
Pirke, K. M., Pahl, J., Schweiger, V. & Warnhoff, M. (1985). Metabolic and endocrine indices of starvation in bulimia: a comparison with anorexia nervosa. Psychiatric Research 15, 3339.CrossRefGoogle ScholarPubMed
Ploog, D. W. & Pirke, K. M. (1987). Psychobiology of anorexia nervosa. Psychological Medicine 17, 843859.CrossRefGoogle ScholarPubMed
Pumariega, A. J., Edwards, P. & Mitchell, C. B. (1984). Anorexia nervosa in black adolescents. Journal of the American Academy of Child and Adolescent Psychiatry 23, 111114.Google ScholarPubMed
Robinson, P. & Andersen, A. (1985). Anorexia nervosa in American blacks. Journal of Psychosomatic Research 19, 183188.CrossRefGoogle ScholarPubMed
Robinson, R. G., Tortosa, M. & Sullivan, J. (1983). Quantitative assessment of psychological state in patients with anorexia nervosa or bulimia: response to caloric stimulus. Psychosomatic Medicine 45, 283291.CrossRefGoogle ScholarPubMed
Rowland, N. E. (1986). Effect of continuous infusions of dexfenfluramine on food intake, body weight and brain amines in rats. Life Sciences 39, 25812586.CrossRefGoogle ScholarPubMed
Russell, G. F. M. (1970). Anorexia nervosa: its identity as an illness treatment. In Modern Trends in Psychological Medicine (ed. Price, J. E.), pp. 131164. Butterworth: London.Google Scholar
Ryle, J. A. (1936). Anorexia nervosa. Lancet ii, 893899.CrossRefGoogle Scholar
Schmidt, U., Tiller, J. M. & Treasure, J. L. (1992). The role of life events and difficulties in the onset of eating disorders. Psychiatric Bulletin (Suppl. 4).Google Scholar
Silber, T. (1984). Anorexia nervosa in black adolescents. Journal of the National Medical Association 76, 2932.Google ScholarPubMed
Silverstone, T. & Russell, G. F. M. (1967). ‘Gastric hunger’ contractions in anorexia nervosa. British Journal of Psychiatry 113, 257263.CrossRefGoogle ScholarPubMed
Solzhenitsyn, A. (1963). On Day in the Life of Ivan Denisovitch. Penguin: London.Google Scholar
Szmukler, G., McCance, C. & McCrone, L. (1986). Anorexia nervosa: a psychiatric case register study from Aberdeen. Psychological Medicine 16, 4958.CrossRefGoogle ScholarPubMed
Thomas, J. P. & Szmukler, G. I. (1985). Anorexia nervosa in patients of Afro-Caribbean extraction. British Journal of Psychiatry 146, 653656.CrossRefGoogle ScholarPubMed
Traskamn, S., Asberg, M., Bertilsson, L. & Sjostrrand, L. (1981). Monoamine metabolites in CSF and suicidal behaviour. Archives of General Psychiatry 38, 631636.CrossRefGoogle Scholar
Treasure, J. L. & Holland, A. J. (1991). Genes and aetiology of eating disorders. In The New Genetics of Mental Illness (ed. McGuffin, P. and Murray, R. M.), pp. 198211. Butterworth-Heinemann: Oxford.CrossRefGoogle Scholar
Vonnegut, K. (1969). Slaughterhouse 5. Penguin: London.Google Scholar
Waller, J. V., Kaufman, R. M. & Deutsch, F. (1940). Anorexia nervosa: a psychosomatic entity. Psychosomatic Medicine 2, 316.CrossRefGoogle Scholar
Willi, J., Giacometti, G. & Limacher, B. (1990). Update on the epidemiology of anorexia nervosa in a defined region of Switzerland. American Journal of Psychiatry 147, 15141517.Google Scholar
Yatham, L. N., Barry, S. & Dinan, T. G. (1989). Serotonin receptors, buspirone and premenstrual syndrome. Lancet i, 14471448.CrossRefGoogle Scholar