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Anxiety and the brain: not by neurochemistry alone1

Published online by Cambridge University Press:  09 July 2009

J. A. Gray
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Abstract

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Type
Editorial
Information
Psychological Medicine , Volume 9 , Issue 4 , November 1979 , pp. 605 - 609
Copyright
Copyright © Cambridge University Press 1979

References

Amsel, A. (1962). Frustrative nonreward in partial reinforcement and discrimination learning: some recent history and a theoretical extension. Psychological Review 69, 306–328.CrossRefGoogle Scholar
Barker, J. L. & Ransom, B. R. (1978). Pentobarbitone pharmacology of mammalian central neurones grown in tissue culture. Journal of Physiology 280, 355–372.CrossRefGoogle ScholarPubMed
Braestrup, G. & Squires, R. F. (1977). Specific benzodiazepine receptors in rat brain characterized by high- affinity [3H]-diazepam binding. Proceedings of the National Academy of Sciences, USA 74, 3805–3809CrossRefGoogle ScholarPubMed
Broadhurst, P. L. (1975). The Maudsley reactive and nonreactive strains of rats: a survey. Behavior Genetics 5, 299–319.CrossRefGoogle ScholarPubMed
Browne, T. R. & Perry, J. K. (1973). Benzodiazepines in the treatment of epilepsy, Epilepsia 14, 277–310.CrossRefGoogle ScholarPubMed
Cook, L. & Sepinwall, J. (1975). Behavioral analysis of the effects and mechanisms of action of benzodiazepines. In Mechanism of Action of Benzodiazepines (ed. Costa, E. and Greengard, P.), pp. 1–28. Raven Press: New York.Google ScholarPubMed
Costa, E. & Greengard, P. (eds.) (1975). Mechanism of Action of Benzodiazepines. Raven Press: New York.Google ScholarPubMed
Crow, T. J. (1973). Catecholamine-containing neurones and electrical self-stimulation. 2. A theoretical interpretation and some psychiatric implications. Psychological Medicine 3, 66–73.CrossRefGoogle ScholarPubMed
Elliott, K. & Whelan, J. (eds.) (1978). Functions of the Septo-Hippocampal System. CIBA Foundation Symposium no. 58 (new series). Elsevier: Amsterdam.Google Scholar
Eysenck, H. J. (1967). The Biological Basis of Personality. C. C. Thomas: Springfield IIIGoogle Scholar
Fuxe, K., Agnati, L. F., Bolme, P., Hökfelt, T., Lidbrink, P., Ljungdahl, A., Perez, de la Mora M. & Ögren, S.-O. (1975). The possible involvement of GABA mechanisms in the action of benzodiazepines on central catecholamine neurons. In Mechanism of Action of Benzodiazepines (ed. Costa, E. and Greengard, P.), pp. 45–61. Raven Press: New York.Google ScholarPubMed
Gray, J. A. (1964). The relation between stimulus intensity and response strength in the context of Pavlovian personality theory. Unpublished Ph.D. thesis: University of London.Google Scholar
Gray, J. A. (1970). Sodium amobarbital, the hippocampal theta rhythm and the partial reinforcement extinction effect. Psychological Review 77, 465–480.CrossRefGoogle ScholarPubMed
Gray, J. A. (1973). Causal theories of personality and how to lest them. In Multivariate Analysis and Psychological Theory (ed. Royce, J. R.), pp. 409–463. Academic Press: London.Google Scholar
Gray, J. A. (1975). Elements of a Two-Process Theory of Learning. Academic Press: London.Google Scholar
Gray, J. A. (1977). Drug effects on fear and frustration: possible limbic site of action of minor tranquillizers. In Handbook of Psychopharmacology (ed. Iversen, L. L.Iversen, S. D. and Snyder, S. H.), pp. 433–529. Plenum: New York.Google Scholar
Gray, J. A. (1978). The 1977 Myers Lecture: The neuropsychology of anxiety. British Journal of Psychology 69, 417–434.CrossRefGoogle Scholar
Gray, J. A., McNaughton, N., James, D. T. D. & Kelly, P. H. (1975). Effect of minor tranquillisers on hippocampal theta rhythm mimicked by depletion of forebrain nor-adrenaline. Nature 258, 424–425.CrossRefGoogle Scholar
Gray, J. A., Feldon, J., Rawlins, J. N. P., Owen, S. & McNaughton, N. (1978). The role of the septo-hippocampal system and its noradrenergic afferents in behavioural responses to nonreward. In Functions of the Septo-Hippocampal System (ed. Elliott, K. and Whelan, J.), pp. 275–300. CIBA Foundation Symposium no. 58 (new series). Elsevier: Amsterdam.Google Scholar
Guidotti, A., Toffano, G. & Costa, E. (1978). An endogenous protein modulates the affinity of GABA and benzodiazepine receptors in rat brain. Nature 275, 553–555.CrossRefGoogle ScholarPubMed
Macdonald, R. L. & Barker, J. L. (1978). Benzodiazepines specifically modulate GABA-mediated postsynaptic inhibition in cultured mammalian neurones. Nature 271, 563–564.CrossRefGoogle ScholarPubMed
Mason, S. T. & Iversen, S. D. (1975). Learning in the absence of forebrain noradrenaline. Nature 258, 422–424.CrossRefGoogle ScholarPubMed
McLennan, H. & Miller, J. J. (1974). The hippocampal control of neuronal discharges in the septum of the rat. Journal of Physiology 237, 607–624.CrossRefGoogle ScholarPubMed
McLennan, H. & Miller, J. J. (1976). Frequency-related inhibitory mechanisms controlling rhythmical activity in the septal area. Journal of Physiology 254, 827–841.CrossRefGoogle ScholarPubMed
Meldrum, B. S. (1975). Epilepsy and y–aminobutyrie acidmediated inhibition. International Review of Neurobiology 17, 1–36.CrossRefGoogle ScholarPubMed
Möhler, H. & Okada, T. (1977). Benzodiazeipne receptor: demonstration in the central nervous system. Science 198, 849–851.CrossRefGoogle ScholarPubMed
Mowrer, O. H. (1947). On the dual nature of learning: a reinterpretation of ‘conditioning’ and ‘problem-solving’. Harvard Educational Review 17, 102–148.Google Scholar
Owen, S., Boarder, M. R., Feldon, J., Gray, J. A. & Fillenz, M. (1979). Role of forebrain noradrenaline in reward and nonreward. Proceedings of the 4th International Catecholamine SymposiumCaliforniaSeptember 1978 (ed. Usdin, E.) (in the press).CrossRefGoogle Scholar
Paul, S. M. & Skolnick, P. (1978). Rapid changes in brain benzodiazepine receptors after experimental seizures. Science 202, 892–894.CrossRefGoogle ScholarPubMed
Randall, L. O. & Kappell, B. (1973). Pharmacological activity of some benzodiazepines and their metabolites. In The Benzodiazepines (ed. Garattini, S., Mussini, E. and Randall, L. O.), pp. 27–51. Raven Press: New York.Google Scholar
Ransom, B. R. & Barker, J. L. (1976). Pentobarbital selectively enhances GABA-mediated post-synaptic inhibition in tissue cultured mouse spinal neurons. Brain Research 114, 530–535.CrossRefGoogle ScholarPubMed
Robertson, H. A., Martin, I. L. & Candy, J. M. (1978). Differences in benzodiazepine receptor binding in Maudsley reactive and Maudsley non-reactive rats. European Journal of Pharmacology 50, 455–457.CrossRefGoogle ScholarPubMed
Rolls, E. T. (1975). The Brain andReward. Pergamon: Oxford.Google Scholar
Schallek, W., Schlosser, W. & Randall, L. O. (1972). Recent developments in the pharmacology of the benzodiazepines. Advances in Pharmacology and Chemotherapy 10, 119–181.CrossRefGoogle Scholar
Soubrié, P., Thiébot, M. H. & Simon, P. (1978). Enhanced suppressive effects of aversive events induced in rats by picrotoxin: evidence for a GABA control on behavioral inhibition. Abstracts of the 11th Congress of the Collegiun Inrernationale Neurophychopharmacologicumx, p. 426.Google Scholar
Squires, C. & Braestrup, R. F. (1977). Benzodiazepine receptors in rat brain. Nature 266, 732–734.CrossRefGoogle ScholarPubMed
Stein, L. (1968). Chemistry of reward and punishment. In Psychopharmacology: A Review of Progress 1957–1967 (ed. Efron, D. H.), pp. 105–123. US Government Printing Office: Washington, D.C.Google Scholar
Stein, L. & Wise, D. C. (1972). Possible etiology of schizophrenia: progressive damage to the noradrenergic reward system by endogenous 6-hydroxydopamine. In Neurotransmitters (ed. Kopin, I.J.). Research Publications of the Association for Nervous and Mental Disease 50, 298–311.Google Scholar
Stein, L., Wise, C. D. & Berger, B. D. (1973). Anti-anxiety action of benzodiazepines: decrease in activity of serotonin neurons in the punishment system. In The Benzodtazepines (ed. Garattini, S.Mussini, E. and Randall, L. O.), pp. 299–326. Raven Press: New York.Google Scholar
Storm-Mathisen, J. (1978). Localization of putative transmitters in the hippocampal formation (with a note on the connections to septum and hypothalamus). In Functions of the Septo-Hippocampal System (ed. Elliott, K. and Whelan, J.), pp. 49–79. CIBA Foundation Symposium no. 58 (new series). Elsevier: Amsterdam.Google Scholar
Ungerstedt, U. (1971). Stereotaxic mapping of the monoamine pathways in the rat brain. Acta Physiologica Scandinavica 82, Suppl. 367, 1–48.CrossRefGoogle Scholar
Williamson, M. J., Paul, S. M. & Skolnick, P. (1978). Labelling of benzodiazepine receptors in vivo. Nature 275, 551–553.CrossRefGoogle ScholarPubMed