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Antisense as an explanatory, experimental and therapeutic tool for psychiatric disorders1

Published online by Cambridge University Press:  09 July 2009

Paul J. Harrison  and
Philip W. J. Burnet
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Abstract

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Type
Editorial
Information
Psychological Medicine , Volume 24 , Issue 2 , May 1994 , pp. 275 - 279
Copyright
Copyright © Cambridge University Press 1994

References

Adelman, J. P., Bond, C. T., Douglass, J. & Herbert, E. (1987). Two mammalian genes transcribed from opposite strands of the same DNA. Science 235, 1514–1517.CrossRefGoogle ScholarPubMed
Akhtar, S. & Juliano, R. L. (1992). Cellular uptake and intracellular fate of antisense oligonucleotides. Trends in Cell Biology 2, 139–144.CrossRefGoogle ScholarPubMed
Caceres, A. & Kosik, K. S. (1990). Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons. Nature 343, 461–463.CrossRefGoogle ScholarPubMed
Chang, E. H., Miller, P. S., Cushman, C., Devadas, K., Pirollo, K. F., Ts'o, P. O. P. & Yu, Z. P. (1991). Antisense inhibition of ras p21 expression that is sensitive for a point mutation. Biochemistry 30, 8283–8286.CrossRefGoogle ScholarPubMed
Chiasson, B. J., Hooper, M. L., Murphy, P. R. & Robertson, H. A. (1992). Antisense oligonucleotide eliminates in vivo expression of c-fos in mammalian brain. European Journal of Pharmacology, Molecular Pharmacology Section 227, 451–453.CrossRefGoogle ScholarPubMed
Cohen, J. (1992). Oligonucleotide therapeutics. Neuroscience Facts 3, part 4, 1–2.Google Scholar
Dolnick, B. J. (1993). Cloning and characterization of a naturally occurring antisense RNA to human thymidylate synthase mRNA. Nucleic Acids Research 21, 1747–1752.CrossRefGoogle ScholarPubMed
Eguchi, Y., Itoh, T. & Tomizawa, J.-I. (1991). Antisense RNA. Annual Review of Biochemistry 60, 631–652.CrossRefGoogle ScholarPubMed
Harrison, P. J. (1993). Antisense: into the brain. Lancet 342, 255–256.CrossRefGoogle ScholarPubMed
Harrison, P. J. ed. (1994). Regulation of Gene Expression and Brain Function. Basic and Clinical Aspects of Neuroscience, vol. 6 (series eds. C. Weil, E. E. Müller and M. O. Thorner). Springer Verlag: Heidelberg.CrossRefGoogle Scholar
Harrison, P. J. & Pearson, R. C. A. (1989). Gene expression and mental disease. Psychological Medicine 19, 813–819.CrossRefGoogle ScholarPubMed
Hélène, C. & Toulmé, J.-J. (1990). Specific regulation of gene expression by antisense, sense and antigene nucleic acids. Biochimica et Biophysica Acta 1049, 99–125.CrossRefGoogle ScholarPubMed
Jirikowski, G. F., Sanna, P. P., Maciejewski-Lenoir, D. & Bloom, F. E. (1992). Reversal of diabetes insipidus in Brattleboro rats: intrahypothalamic injection of vasopressin mRNA. Science 255, 996–998.CrossRefGoogle ScholarPubMed
Katsuki, M., Sato, M., Kimura, M., Yokoyama, M., Kobayashi, K. & Nomura, T. (1988). Conversion of normal behaviour to shiverer by myelin basic protein antisense cDNA in transgenic mice. Science 241, 593–596.CrossRefGoogle ScholarPubMed
Khan, I. M. & Coulson, J. M. (1993). A novel method to stabilise antisense oligonucleotides against exonuclease degradation. Nucleic Acids Research 21, 2957–2958.CrossRefGoogle ScholarPubMed
Lancet Editorial (1991). Antisensibility: progress and prospects. Lancet 338, 1427–1428.CrossRefGoogle Scholar
LeBlanc, A. C., Kovacs, D. M., Chen, H. Y., Villaré, F., Tykocinski, M., Autilio-Gambetti, L. & Gambetti, P. (1992). Role of amyloid precursor protein (APP): study with antisense transfection of human neuroblastoma cells. Journal of Neuroscience Research 31, 635–645.CrossRefGoogle ScholarPubMed
Leonetti, J.-P., Machy, P., Degols, G., Lebleu, B. & Leserman, L. (1990). Antibody-targeted liposomes containing oligodeoxyribo-nucleotides complementary to viral RNA selectively inhibit viral replication. Proceedings of the National Academy of Sciences, USA 87, 2448–2451.CrossRefGoogle Scholar
Listerud, M., Brussaard, A. B., Devay, P., Colman, D. R. & Role, L. W. (1991). Functional contribution of neuronal AChR subunits revealed by antisense oligonucleotides. Science 254, 1518–1521.CrossRefGoogle ScholarPubMed
Loke, S. L., Stein, C. A., Zhang, X. H., Mori, K., Nakanishi, M., Subasinghe, C., Cohen, J. S. & Neckers, L. M. (1989). Characterization of oligonucleotide transport into living cells. Proceedings of the National Academy of Sciences, USA 86, 3474–3478.CrossRefGoogle ScholarPubMed
Moffat, A. S. (1991). Making sense of antisense. Science 253, 510–511.CrossRefGoogle ScholarPubMed
Moser, M., Oesch, B. & Büeler, H. (1993). An anti-prion protein? Nature 362, 213–214.CrossRefGoogle ScholarPubMed
Neve, R. L. (1993). Adenovirus vectors enter the brain. Trends in Neurosciences 16, 251–253.CrossRefGoogle ScholarPubMed
Prusiner, S. B. (1992). Natural and experimental prion diseases of humans and animals. Current Opinion in Neurobiology 5, 638–647.CrossRefGoogle Scholar
Simons, M., Edelman, E. R., DeKeyser, J.-L., Langer, R. & Rosenberg, R. D. (1992). Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo. Nature 359, 67–70.CrossRefGoogle ScholarPubMed
Stein, C. A. & Cheng, Y.-C. (1993). Antisense oligonucleotides as therapeutic agents – is the bullet really magical? Science 261, 1004–1012.CrossRefGoogle ScholarPubMed
Takayama, K. M. & Inouye, M. (1990). Antisense RNA. Critical Reviews in Biochemistry and Molecular Biology 25, 155–184.CrossRefGoogle ScholarPubMed
Vanderklish, P., Neve, R., Bahr, B. A., Arai, A., Hennegriff, M., Larson, J. & Lynch, G. (1992). Translational suppression of a glutamate receptor subunit impairs long-term potentiation. Synapse 12, 333–337.CrossRefGoogle ScholarPubMed
Van Tol, H. H. M., Bunzow, J. R., Guan, H.-C., Sunahara, R. K., Seeman, P., Niznik, H. B. & Civelli, O. (1991). Cloning of the gene for a human D4 receptor with high affinity for the antipsychotic clozapine. Nature 350, 610–614.CrossRefGoogle ScholarPubMed
Wagner, R. W., Matteucci, M. D., Lewis, J. G., Gutierrez, A. J., Moulds, C. & Froehler, B. C. (1993). Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimidines. Science 260, 1510–1513.CrossRefGoogle ScholarPubMed
Wahlestedt, C., Merlo, E., Pich, M., Koob, G. F., Yee, F. & Heilig, M. (1993 a). Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligonucleotides. Science 259, 528–531.CrossRefGoogle Scholar
Wahlestedt, C., Golanov, E., Yamamoto, S., Yee, F., Ericson, H., Yoo, H., Inturrisi, C. E. & Reis, D. J. (1993 b). Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions. Nature 363, 260–263.CrossRefGoogle ScholarPubMed
Weintraub, H. M. (1990). Antisense RNA and DNA. Scientific American 262, 34–40.CrossRefGoogle ScholarPubMed
Weiss, B., Zhou, L.-W., Zhang, S.-P. & Qin, Z.-H. (1993). Antisense oligonucleotide inhibits D2 receptor-mediated behavior and D2 messenger RNA. Neuroscience 55, 607–612.CrossRefGoogle Scholar
Whitesell, L., Geselowitz, D., Chavany, C., Fahmy, B., Walbridge, S., Alger, J. R. & Neckers, L. M. (1993). Stability, clearance, and disposition of intraventricularly administered oligodeoxynucleotides: implications for therapeutic application within the central nervous system. Proceedings of the National Academy of Sciences, USA 90, 4665–4669.CrossRefGoogle ScholarPubMed
Zhu, N., Liggitt, D. & Debs, R. (1993). Systemic gene expression after intravenous DNA delivery into adult mice. Science 261, 209–212.CrossRefGoogle ScholarPubMed