Hostname: page-component-78c5997874-j824f Total loading time: 0 Render date: 2024-11-17T20:14:29.276Z Has data issue: false hasContentIssue false
  • English
  • Français

Akinetic mutism with recovery after repeated carbon monoxide poisoning

Published online by Cambridge University Press:  09 July 2009

J. Sydney Smith ,
H. Brierley  and
S. Brandon
J. Sydney Smith
Affiliation:
Department of Psychological Medicine, University of Newcastle upon Tyne
H. Brierley
Affiliation:
Department of Psychological Medicine, University of Newcastle upon Tyne
S. Brandon
Affiliation:
Royal Victoria Infirmary, Newcastle upon Tyne
Get access Rights & Permissions [Opens in a new window]

Summary

A 27-year-old man developed signs of personality change after exposure to carbon monoxide. One month later a second exposure was followed by an akinetic mute state with unusual motor seizures, probably associated with tentorial herniation and brain-stem compression. Elimination of carbon monoxide was unduly prolonged after the second exposure. The patient showed clinical evidence of dementia, but there has been a gradual improvement in cognitive and social functioning over two years.

Type
Research Article
Information
Psychological Medicine , Volume 1 , Issue 2 , February 1971 , pp. 172 - 177
Copyright
Copyright © Cambridge University Press 1971

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Abe, M., and Hara, Y. (1963). A case of an apallic syndrome as observed after an acute CO toxicosis (In Japanese). Fukuoka Acta Medica, 54, 1057–1061.Google Scholar
Arnott, G., Petit, H., and Chabrier, A. (1964). Coma oxycarboné. Survenue, après important intervalle libre, d'un syndrome akinéto-hypertonique avec trismus et mutisme. Evolution favourable. Lille Medical, 9, 728–733.Google Scholar
Berlyne, N., and Strachan, M. (1968). Neuropsychiatric sequelae of attempted hanging. British Journal of Psychiatry, 114, 411–422.CrossRefGoogle ScholarPubMed
Bour, H., Pasquier, P., and Bertrand-Hardy, J. M. (1966). Le coma oxycarboné. Étude générale, clinique, biologique et thérapeutique de 290 cas. Semaine des Hopitaux de Paris, 42, 1839–1861.Google Scholar
Bour, H., Tutin, M., and Pasquier, P. (1967). The central nervous System and carbon monoxide poisoning. I. Clinical data with reference to 20 fatal cases. In Progress in Brain Research, Vol. 24. Edited by Bour, H. and McA, I.. Ledingham. Elsevier: London.Google Scholar
Cravioto, H., Silberman, J., and Feigin, I. (1960). A clinical and pathological study of akinetic mutism. Neurology, 10, 10–21.CrossRefGoogle ScholarPubMed
Denny-Brown, D. (1962). The Basal Ganglia. Oxford University Press: London.Google Scholar
Dereux, J., and Catoir, J. (1952). Deux complications nerveuses particulières de l'intoxication par l'oxyde de carbone: syndrome parkinsonien transitoire avec inertia et mutisme, et chorée chronique. Revue Neurologique, 86, 40–43.Google Scholar
Gordon, E. B. (1965). Carbon monoxide encephalopathy. British Medical Journal, 1, 1232.CrossRefGoogle ScholarPubMed
Kretschmer, E. (1940). Das apallische Syndrome. Zeit-schrift für die gesamte Neurologie und Psychiatrie, 169, 576–579.CrossRefGoogle Scholar
Lapresle, J., and Fardeau, M. (1967). The central nervous System and carbon monoxide poisoning. II. Anatomical study of brain lesions following intoxication with carbon monoxide (22 cases). In Progress in Brain Research, Vol. 24. Edited by Bour, H. and McA, I.. Ledingham. Elsevier: London.Google Scholar
Mackintosh, T. F. (1965). Akinetic mutism following coal gas poisoning with subsequent recovery. Postgraduate Medical Journal, 41, 567–573.CrossRefGoogle ScholarPubMed
Mouron, P., Tatossian, A., Delmont, J. P., Pinsard, N., and Jacquet, P. (1963). Les manifestations neurologiques relardées de l'inloxication oxycarbonée aigue: syndrome akinetique avce mutisme, sans hypertonie, et d'evolution regressive. Marseille Médical, 100, 618–621.Google Scholar
Nick, J., Dérobert, L., Fournier, E., and Escourolle, R. (1956). Manifestations neuropsychiatriques post intervallaires de l'intoxication oxycarbonée aigue (10 cas). Annales de Médicine Légale et de Criminologie, 36, 208–223.Google Scholar
Okuma, T., Ishino, H., Sunami, Y., and Motoike, M. (1968). An autopsy case of relapsing form carbon monoxide intoxication with special reference to the apallic syndrome and sleep cycle pattern. Folia Psychiatrica et Neurologica Japonica, 22, 43–53.Google Scholar
Ramsey, T. L., and Eilmann, H. J. (1931–1932). Carbon monoxide acute and chronic poisoning and experimental studies. Journal of Laboratory and Clinical Medicine, 17, 415–427.Google Scholar
Roughton, F. J., and Root, W. S. (1945). The fate of CO in the body during recovery from mild carbon monoxide poisoning in man. American Journal of Physiology, 145, 239–252.CrossRefGoogle Scholar
Schott, B., Lejeune, E., and Bourrat, C. (1961). Les manifestations neurologiques initiales et retardées de l'intoxication oxycarbonée aigue. Journal de Medicine, 42, 531–559.Google Scholar
Smith, J. S., and Brandon, S. (1970). Acute carbon monoxidc poisoning—3 years experience in a defined population, Postgraduute Medical Journal, 46, 65–70.CrossRefGoogle Scholar