Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-28T15:22:11.732Z Has data issue: false hasContentIssue false

Age patterns in the prevalence of DSM-IV depressive/anxiety disorders with and without physical co-morbidity

Published online by Cambridge University Press:  19 May 2008

K. M. Scott*
Affiliation:
Department of Psychological Medicine, Otago University, Wellington, New Zealand
M. Von Korff
Affiliation:
Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, WA, USA
J. Alonso
Affiliation:
Health Services Research Unit, Institute Municipal d'Investigacio Medica (IMIM), and CIBER en Epidemiologia y Salud Publica (CIBERESP), Barcelona, Spain
M. Angermeyer
Affiliation:
Center for Public Mental Health, Austria
E. J. Bromet
Affiliation:
SUNY Stony Brook, Stony Brook, New York, USA
R. Bruffaerts
Affiliation:
Department of Neurosciences and Psychiatry, University Hospital, Gasthuisberg, Leuven, Belgium
G. de Girolamo
Affiliation:
Regional Health Care Agency, Emilia-Romagna Region, Bologna, Italy
R. de Graaf
Affiliation:
Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands
A. Fernandez
Affiliation:
Fundació Sant Joan de Déu Research and Development Unit, Barcelona, Spain
O. Gureje
Affiliation:
Department of Psychiatry, University College Hospital, Ibadan, Nigeria
Y. He
Affiliation:
Shanghai Mental Health Center, Shanghai, People's Republic of China
R. C. Kessler
Affiliation:
Department of Health Care Policy, Harvard Medical School, Boston, MA, USA
V. Kovess
Affiliation:
Fondation MGEN Pour La Santé Publique, Université Paris 5, Paris, France
D. Levinson
Affiliation:
Mental Health Services, Ministry of Health, Jerusalem, Israel
M. E. Medina-Mora
Affiliation:
Department of Epidemiology, National Institute of Psychiatry, Mexico City, Mexico
Z. Mneimneh
Affiliation:
Institute for Development Research Advocacy and Applied Care (IDRAAC), Beirut, Lebanon
M. A. Oakley Browne
Affiliation:
Department of Rural and Indigenous Health, School of Rural Health, Monash University, Victoria, Australia
J. Posada-Villa
Affiliation:
Colegio Mayor de Cundinamarca University, Bogota, Colombia
H. Tachimori
Affiliation:
National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
D. Williams
Affiliation:
Department of Society, Human Development and Health, Harvard School of Public Health, Harvard University, Boston, MA, USA
*
*Address for correspondence: K. M Scott, Ph.D., Department of Psychological Medicine, Otago University, Wellington, PO Box 7343, Wellington South, New Zealand. (Email: [email protected])

Abstract

Background

Physical morbidity is a potent risk factor for depression onset and clearly increases with age, yet prior research has often found depressive disorders to decrease with age. This study tests the possibility that the relationship between age and mental disorders differs as a function of physical co-morbidity.

Method

Eighteen general population surveys were carried out among household-residing adults as part of the World Mental Health (WMH) surveys initiative (n=42 697). DSM-IV disorders were assessed using face-to-face interviews with the Composite International Diagnostic Interview (CIDI 3.0). The effect of age was estimated for 12-month depressive and/or anxiety disorders with and without physical or pain co-morbidity, and for physical and/or pain conditions without mental co-morbidity.

Results

Depressive and anxiety disorders decreased with age, a result that cannot be explained by organic exclusion criteria. No significant difference was found in the relationship between mental disorders and age as a function of physical/pain co-morbidity. The majority of older persons have chronic physical or pain conditions without co-morbid mental disorders; by contrast, the majority of those with mental disorders have physical/pain co-morbidity, particularly among the older age groups.

Conclusions

CIDI-diagnosed depressive and anxiety disorders in the general population decrease with age, despite greatly increasing physical morbidity with age. Physical morbidity among persons with mental disorder is the norm, particularly in older populations. Health professionals, including mental health professionals, need to address barriers to the management of physical co-morbidity among those with mental disorders.

Type
Original Articles
Copyright
Copyright © 2008 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Alonso, J, Angermeyer, MC, Bernert, S, Bruffaerts, R, Brugha, TS, Bryson, H, de Girolamo, G, Graaf, R, Demyttenaere, K, Gasquet, I, Haro, JM, Katz, SJ, Kessler, RC, Kovess, V, Lepine, JP, Ormel, J, Polidori, G, Russo, LJ, Vilagut, G, Almansa, J, Arbabzadeh-Bouchez, S, Autonell, J, Bernal, M, Buist-Bouwman, MA, Codony, M, Domingo-Salvany, A, Ferrer, M, Joo, SS, Martinez-Alonso, M, Matschinger, H, Mazzi, F, Morgan, Z, Morosini, P, Palacin, C, Romera, B, Taub, N, Vollebergh, WA (2004). Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatrica Scandinavica Supplementum 420, 2127.Google Scholar
APA (1994). DSM-IV: Diagnostic and Statistical Manual of Mental Disorders, 4th edn. American Psychiatric Association: Washington, DC.Google Scholar
Beekman, ATF, Copeland, JRM, Prince, MJ (1999). Review of community prevalence of depression in later life. British Journal of Psychiatry 174, 307311.CrossRefGoogle ScholarPubMed
Beekman, ATF, Deeg, DJH, Van Tilburg, T, Smit, JH, Hooijer, C, Van Tilburg, W (1995). Major and minor depression in later life: a study of prevalence and risk factors. Journal of Affective Disorders 36, 6575.CrossRefGoogle ScholarPubMed
Blazer, DG, Hybels, CF (2005). Origins of depression in later life. Psychological Medicine 35, 12411252.CrossRefGoogle ScholarPubMed
Brilman, E, Ormel, J (2001). Life events, difficulties and onset of depressive episodes in later life. Psychological Medicine 31, 859869.CrossRefGoogle ScholarPubMed
Brown, S, Inskip, H, Barraclough, B (2000). Causes of the excess mortality of schizophrenia. British Journal of Psychiatry 177, 212217.CrossRefGoogle ScholarPubMed
Buist-Bouwman, MA, de Graaf, R, Vollebergh, WAM, Ormel, J (2005). Comorbidity of physical and mental disorders and the effect on work-loss days. Acta Psychiatrica Scandinavica 111, 436443.CrossRefGoogle ScholarPubMed
Christensen, H, Jorm, AF, Mackinnon, AJ, Korten, AE, Jacomb, PA, Henderson, AS, Rodgers, B (1999). Age differences in depression and anxiety symptoms: a structural equation modelling analysis of data from a general population sample. Psychological Medicine 29, 325339.CrossRefGoogle ScholarPubMed
Coyne, JC, Thompson, R, Klinkman, MS, Nease, JR (2002). Emotional disorders in primary care. Journal of Consulting and Clinical Psychology 70, 798809.CrossRefGoogle ScholarPubMed
de Graaf, R, Bijl, RV, Ravelli, A, Smit, F, Vollebergh, WAM (2002). Predictors of first incidence of DSM-III-R psychiatric disorders in the general population: findings from the Netherlands Mental Health Survey and Incidence Study. Acta Psychiatrica Scandinavica 106, 303313.CrossRefGoogle ScholarPubMed
Dew, MA (1998). Psychiatric disorder in the context of physical illness. In Adversity, Stress and Psychopathology (ed. Dohrenwend, B. P.), pp. 177218. Oxford University Press: New York.CrossRefGoogle Scholar
Evans, DL, Charney, DS, Lewis, L, Golden, JM, Ranga Rama Krishnan, K, Nemeroff, CB, Bremner, JD, Carney, RM, Coyne, JC, Delong, MR, Frasure-Smith, N, Glassman, AH, Gold, PW, Grant, I, Gwyther, L, Ironson, G, Johnson, RL, Kanner, AM, Katon, WJ, Kaufmann, PG, Keefe, FJ, Ketter, T, Laughren, TP, Leserman, J, Lyketsos, CG, McDonald, WM, McEwan, BS, Miller, AH, Musselman, D, O'Connor, C, Petitto, JM, Pollock, BG, Robinson, RG, Roose, SP, Rowland, J, Sheline, Y, Sheps, DS, Simon, G, Spiegel, D, Stunkard, A, Sunderland, T, Tibbits, P, Valvo, WJ (2005). Mood disorders in the medically ill: scientific review and recommendations. Biological Psychiatry 58, 175189.CrossRefGoogle Scholar
Friedli, L, Dardis, C (2002). Not all in the mind: mental health service user perspectives on physical health. Journal of Mental Health Promotion 1, 3646.Google Scholar
Gallo, JJ, Anthony, JC, Muthén, BO (1994). Age differences in the symptoms of depression: a latent trait analysis. Journal of Gerontology 49, 251264.CrossRefGoogle ScholarPubMed
Harter, MC, Conway, KP, Merikangas, KR (2003). Associations between anxiety disorders and physical illness. European Archives of Psychiatry and Clinical Neuroscience 253, 313320.CrossRefGoogle ScholarPubMed
Heithoff, K (1995). Does the ECA underestimate the prevalence of late-life depression? Journal of the American Geriatrics Society 43, 26.CrossRefGoogle ScholarPubMed
Henderson, AS, Jorm, AF, Korten, A, Jacomb, P, Christensen, H, Rodgers, B (1998). Symptoms of depression and anxiety during adult life: evidence of a decline in prevalence with age. Psychological Medicine 28, 13211328.CrossRefGoogle ScholarPubMed
Hybels, CF, Blazer, D (2002). Epidemiology and geriatric psychiatry. In Textbook in Psychiatric Epidemiology (ed. Tsuang, M. T. and Tohen, M.), pp. 603628. Wiley-Liss Inc.: New York.Google Scholar
Hyland, B, Judd, F, Davidson, S, Jolley, D, Hocking, B (2003). Case managers' attitudes to the physical health of their patients. Australian and New Zealand Journal of Psychiatry 37, 710714.CrossRefGoogle Scholar
Jorm, AF (2000). Does old age reduce the risk of anxiety and depression? A review of epidemiological studies across the adult life span. Psychological Medicine 30, 1122.CrossRefGoogle ScholarPubMed
Karel, MJ (1997). Aging and depression: vulnerability and stress across adulthood. Clinical Psychology Review 17, 847879.CrossRefGoogle ScholarPubMed
Katon, W, Von Korff, M, Lin, E, Bush, T, Ormel, J (1992). Adequacy and duration of antidepressant treatment in primary care. Medical Care 30, 6776.CrossRefGoogle ScholarPubMed
Kehoe, R, Wu, S-Y, Leske, MC, Chylack, LT (1994). Comparing self-reported and physician reported medical history. American Journal of Epidemiology 139, 813818.CrossRefGoogle ScholarPubMed
Kessler, R, Berglund, P, Demler, O, Jin, R, Koretz, D, Merikangas, KR, Rush, AJ, Walters, EE, Wang, PS (2003 a). The epidemiology of major depressive disorder. Results from the National Comorbidity Survey Replication (NCS-R). Journal of the American Medical Association 289, 30953105.CrossRefGoogle ScholarPubMed
Kessler, R, Foster, C, Webster, PS, House, JS (1992). The relationship between age and depressive symptoms in two national surveys. Psychology and Aging 7, 119126.CrossRefGoogle ScholarPubMed
Kessler, RC, Bergland, P, Chiu, WT, Demler, O, Heeringa, S, Hiripi, E, Jin, R, Pennell, B-E, Walters, EE, Zaslavsky, A, Zheung, H (2004). The US National Comorbidity Survey Replication (NCS-R): design and field procedures. International Journal of Methods in Psychiatric Research 13, 6992.CrossRefGoogle ScholarPubMed
Kessler, RC, Ormel, J, Demler, O, Stang, PE (2003 b). Comorbid mental disorders account for the role impairment of commonly occurring chronic physical disorders: results from the National Comorbidity Survey. Journal of Occupational and Environmental Medicine 45, 12571266.CrossRefGoogle ScholarPubMed
Kessler, RC, Ustun, B (2004). The World Mental Health (WMH) Survey Initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI). International Journal of Methods in Psychiatric Research 13, 93121.CrossRefGoogle ScholarPubMed
Knäuper, B, Wittchen, H-U (1994). Diagnosing major depression in the elderly: evidence for response bias in standardized diagnostic interviews? Journal of Psychiatric Research 28, 147164.CrossRefGoogle ScholarPubMed
Kriegsman, DM, Penninx, BW, Van Eijk, JT, Boeke, AJ, Deeg, DJ (1996). Self-reports and general practitioner information on the presence of chronic diseases in community dwelling elderly. Journal of Clinical Epidemiology 49, 14071417.CrossRefGoogle ScholarPubMed
Krishnan, KRR (2002). Biological risk factors in late life depression. Biological Psychiatry 52, 185192.CrossRefGoogle ScholarPubMed
Mulsant, BH, Ganguli, M (1999). Epidemiology and diagnosis of depression in late life. Journal of Clinical Psychiatry 60 (Suppl. 20), 915.Google ScholarPubMed
NCHS (1994). Evaluation of National Health Interview Survey diagnostic reporting. Vital and Health Statistics, Series 2 120, 1116.Google Scholar
Newmann, JP (1989). Aging and depression. Psychology and Aging 4, 150165.CrossRefGoogle ScholarPubMed
O'Connor, DW (2006). Do older Australians truly have low rates of anxiety and depression? A critique of the 1997 National Survey of Mental Health and Wellbeing. Australian and New Zealand Journal of Psychiatry 40, 623631.CrossRefGoogle ScholarPubMed
Ormel, J, Koeter, M, van den Brink, W, van de Willige, G (1991). Recognition, management and course of anxiety and depression in general practice. Archives of General Psychiatry 48, 700706.CrossRefGoogle ScholarPubMed
Pirkola, SP, Isometsä, E, Suvisaari, J, Aro, H, Joukamaa, M, Poikolainen, K, Koskinen, S, Aromaa, A, Lönnqvist, JK (2005). DSM-IV mood, anxiety and alcohol use disorders and their comorbidity in the Finnish general population. Results from the Health 2000 study. Social Psychiatry and Psychiatric Epidemiology 40, 110.CrossRefGoogle ScholarPubMed
Regier, DA, Boyd, JH, Burke, JDJ, Rae, DS, Myers, JK, Kramer, M, Robins, LN, George, LK, Karno, M, Locke, BZ (1988). One-month prevalence of mental disorders in the United States. Archives of General Psychiatry 45, 977986.CrossRefGoogle ScholarPubMed
Schoevers, RA, Beekman, ATF, Deeg, DJ, Geerlings, MI, Jonker, C, Van Tilburg, W (2000). Risk factors for depression in later life; results of a prospective community based study (AMSTEL). Journal of Affective Disorders 59, 127137.CrossRefGoogle ScholarPubMed
Scott, KM, Bruffaerts, R, Tsang, A, Ormel, J, Alonso, J, Angermeyer, MC, Benjet, C, Bromet, E, de Girolamo, G, de Graaf, R, Gasquet, I, Gureye, O, Haro, JM, He, Y, Kessler, RC, Levinson, D, Mneimneh, ZN, Oakley Browne, MA, Posada-Villa, J, Stein, DJ, Takeshima, T, Von Korff, M (2007). Depression-anxiety relationships with chronic physical conditions: results from the World Mental Health surveys. Journal of Affective Disorders 103, 113120.CrossRefGoogle ScholarPubMed
Scott, KM, Von Korff, M, Alonso, J, Angermeyer, MC, Bromet, E, Fayyad, J, de Girolamo, G, Demyttenaere, K, Gasquet, I, Gureje, O, Haro, JM, He, Y, Kessler, RC, Levinson, D, Medina Mora, ME, Oakley Browne, MA, Ormel, J, Posada-Villa, J, Watanabe, M, Williams, D (in press). Mental–physical comorbidity and its relationship with disability: results from the World Mental Health surveys. Psychological Medicine.Google Scholar
Siegler, IC, Bastian, LA, Steffens, DC, Bosworth, HB, Costa, PT (2002). Behavioural medicine and aging. Journal of Consulting and Clinical Psychology 70, 843851.CrossRefGoogle ScholarPubMed
Skoog, I (2004). Psychiatric epidemiology of old age: the H70 study – the NAPE lecture 2003. Acta Psychiatrica Scandinavica 109, 418.CrossRefGoogle Scholar
Snowdon, J (2001). Is depression more prevalent in old age? Australian and New Zealand Journal of Psychiatry 35, 782787.CrossRefGoogle ScholarPubMed
Stordal, E, Mykletun, A, Dahl, AA (2003). The association between age and depression in the general population: a multivariate examination. Acta Psychiatrica Scandinavica 107, 132141.CrossRefGoogle ScholarPubMed
SUDAAN (2002). SUDAAN Inc., Research Triangle Institute, Research Triangle Park: NC.Google Scholar
Troller, JN, Anderson, TM, Sachdev, PS, Brodaty, H, Andrews, G (2007). Age shall not weary them: mental health in the middle-aged and the elderly. Australian and New Zealand Journal of Psychiatry 41, 581589.CrossRefGoogle Scholar
van't Veer-Tazelaar, PJ, van Marwijk, HWJ, Jansen, APD, Rijmen, F, Kostense, PJ, van Oppen, P, van Hout, HPJ, Stalman, WAB, Beekman, ATF (2008). Depression in old age (75+), the PIKO study. Journal of Affective Disorders 106, 295299.CrossRefGoogle ScholarPubMed
Villamil, E, Huppert, FA, Melzer, D (2006). Low prevalence of depression and anxiety is linked to statutory retirement ages rather than personal work exit: a national survey. Psychological Medicine 36, 9991009.CrossRefGoogle ScholarPubMed
Wells, JE, Oakley Browne, MA, Scott, KM, McGee, MA, Baxter, J, Kokaua, J (2006). Prevalence, interference with life and severity of DSM-IV disorders in Te Rau Hinengaro: The New Zealand Mental Health Survey. Australian and New Zealand Journal of Psychiatry 40, 845854.CrossRefGoogle ScholarPubMed
Wells, KB, Golding, JM, Burnam, MA (1989). Affective, substance use, and anxiety disorders in persons with arthritis, diabetes, heart disease, high blood pressure, or chronic lung conditions. General Hospital Psychiatry 11, 320327.CrossRefGoogle ScholarPubMed