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Adolescent development of psychosis as an outcome of hearing impairment: a 10-year longitudinal study

Published online by Cambridge University Press:  19 May 2010

M. van der Werf ,
V. Thewissen ,
M. D. Dominguez ,
R. Lieb ,
H. Wittchen  and
J. van Os
M. van der Werf*
Affiliation:
Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON Graduate School of Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands
V. Thewissen
Affiliation:
Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON Graduate School of Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands Open University of the Netherlands, Faculty of Psychology, Heerlen, The Netherlands
M. D. Dominguez
Affiliation:
Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON Graduate School of Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands
R. Lieb
Affiliation:
Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology Unit, Munich, Germany Epidemiology and Health Psychology, Institute of Psychology, University of Basel, Basel, Switzerland
H. Wittchen
Affiliation:
Max Planck Institute of Psychiatry, Clinical Psychology and Epidemiology Unit, Munich, Germany Institute of Clinical Psychology and Psychotherapy, Technical University Dresden, Dresden, Germany
J. van Os
Affiliation:
Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON Graduate School of Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands King's College London, King's Health Partners, Department of Psychosis Studies, Institute of Psychiatry, London, UK
*
*Address for correspondence: M. van der Werf, Department of Psychiatry and Neuropsychology, Maastricht University Medical Centre, PO Box 616 (VIJV), 6200 MD Maastricht, The Netherlands. (Email: [email protected])
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Abstract

Background

It has long been acknowledged that hearing impairment may increase the risk for psychotic experiences. Recent work suggests that young people in particular may be at risk, indicating a possible developmental mechanism.

Method

The hypothesis that individuals exposed to hearing impairment in early adolescence would display the highest risk for psychotic symptoms was examined in a prospective cohort study of a population sample of originally 3021 adolescents and young adults aged 14–24 years at baseline, in Munich, Germany (Early Developmental Stages of Psychopathology Study). The expression of psychosis was assessed at multiple time points over a period of up to 10 years, using a diagnostic interview (Munich Composite International Diagnostic Interview; CIDI) administered by clinical psychologists.

Results

Hearing impairment was associated with CIDI psychotic symptoms [odds ratio (OR) 2.04, 95% confidence interval (CI) 1.10–3.81], particularly more severe psychotic symptoms (OR 5.66, 95% CI 1.64–19.49). The association between hearing impairment and CIDI psychotic symptoms was much stronger in the youngest group aged 14–17 years at baseline (OR 3.28, 95% CI 1.54–7.01) than in the older group aged 18–24 years at baseline (OR 0.82, 95% CI 0.24–2.84).

Conclusions

The finding of an age-specific association between hearing impairment and psychotic experiences suggests that disruption of development at a critical adolescent phase, in interaction with other personal and social vulnerabilities, may increase the risk for psychotic symptoms.

Keywords

Adolescentsdevelopmenthearing impairmentpsychosissocial cognition
Type
Original Articles
Information
Psychological Medicine , Volume 41 , Issue 3 , March 2011 , pp. 477 - 485
Copyright
Copyright © Cambridge University Press 2010

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References

Arrindell, WA, Ettema, JHM (eds) (2003). SCL-90. Handleiding bij een Multidimensionale Psychopathologie Indicator [SCL-90. Manual of a Multidimensional Indicator of Psychopathology]. Swets Test Publisher: Lisse.Google Scholar
Bentall, RP (1990). The illusion of reality: a review and integration of psychological research on hallucinations. Psychological Bulletin 107, 82–95.CrossRefGoogle ScholarPubMed
Bess, FH, Dodd-Murphy, J, Parker, RA (1998). Children with minimal sensorineural hearing loss: prevalence, educational performance, and functional status. Ear and Hearing 19, 339–354.CrossRefGoogle ScholarPubMed
Bonicatto, S, Dew, MA, Soria, JJ, Seghezzo, ME (1997). Validity and reliability of Symptom Checklist ‘90 (SCL90) in an Argentine population sample. Social Psychiatry and Psychiatric Epidemiology 32, 332–338.CrossRefGoogle Scholar
Boydell, J, van Os, J, McKenzie, K, Murray, RM (2004). The association of inequality with the incidence of schizophrenia – an ecological study. Social Psychiatry and Psychiatric Epidemiology 39, 597–599.CrossRefGoogle ScholarPubMed
Brown, AS, Cohen, P, Greenwald, S, Susser, E (2000). Nonaffective psychosis after prenatal exposure to rubella. American Journal of Psychiatry 157, 438–443.CrossRefGoogle ScholarPubMed
Cannon, M, Caspi, A, Moffitt, TE, Harrington, H, Taylor, A, Murray, RM, Poulton, R (2002). Evidence for early-childhood, pan-developmental impairment specific to schizophreniform disorder: results from a longitudinal birth cohort. Archives of General Psychiatry 59, 449–456.CrossRefGoogle ScholarPubMed
Chapman, LJ, Chapman, JP, Kwapil, TR, Eckblad, M, Zinser, MC (1994). Putatively psychosis-prone subjects 10 years later. Journal of Abnormal Psychology 103, 171–183.CrossRefGoogle ScholarPubMed
Cooper, AF, Curry, AR (1976). The pathology of deafness in the paranoid and affective psychoses of later life. Journal of Psychosomatic Research 20, 97–105.CrossRefGoogle ScholarPubMed
Cougnard, A, Marcelis, M, Myin-Germeys, I, De Graaf, R, Vollebergh, W, Krabbendam, L, Lieb, R, Wittchen, HU, Henquet, C, Spauwen, J, Van Os, J (2007). Does normal developmental expression of psychosis combine with environmental risk to cause persistence of psychosis? A psychosis proneness–persistence model. Psychological Medicine 37, 513–527.CrossRefGoogle ScholarPubMed
Dalman, C, Allebeck, P, Gunnell, D, Harrison, G, Kristensson, K, Lewis, G, Lofving, S, Rasmussen, F, Wicks, S, Karlsson, H (2008). Infections in the CNS during childhood and the risk of subsequent psychotic illness: a cohort study of more than one million Swedish subjects. American Journal of Psychiatry 165, 59–65.CrossRefGoogle ScholarPubMed
David, A, Malmberg, A, Lewis, G, Brandt, L, Allebeck, P (1995). Are there neurological and sensory risk factors for schizophrenia? Schizophrenia Research 14, 247–251.CrossRefGoogle ScholarPubMed
Derogatis, LR (1983). SCL-90-R Administration, Scoring and Procedures Manual-II. Clinical Psychometric Research: Towson, MD.Google Scholar
Dominguez, MD, Wichers, M, Lieb, R, Wittchen, HU, van Os, J (2009). Evidence that onset of clinical psychosis is an outcome of progressively more persistent subclinical psychotic experiences: an 8-year cohort study. Schizophrenia Bulletin. Published online: 21 May 2009. doi: 10.1093/schbul/sbp022.Google ScholarPubMed
Fortnum, H, Davis, A (1993). Hearing impairment in children after bacterial meningitis: incidence and resource implications. British Journal of Audiology 27, 43–52.CrossRefGoogle ScholarPubMed
Frith, CD (1992). The Cognitive Neuropsychology of Schizophrenia. Lawrence Erlbaum Associates: Hove, UK.Google Scholar
Hanssen, M, Bak, M, Bijl, R, Vollebergh, W, van Os, J (2005). The incidence and outcome of subclinical psychotic experiences in the general population. British Journal of Clinical Psychology 44, 181–191.CrossRefGoogle ScholarPubMed
Henquet, C, Krabbendam, L, Spauwen, J, Kaplan, C, Lieb, R, Wittchen, HU, van Os, J (2005). Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people. British Medical Journal (Clinical Research Edition) 330, 11.CrossRefGoogle ScholarPubMed
Herrgard, E, Karjalainen, S, Martikainen, A, Heinonen, K (1995). Hearing loss at the age of 5 years of children born preterm – a matter of definition. Acta Paediatrica 84, 1160–1164.CrossRefGoogle ScholarPubMed
Janssen, I, Krabbendam, L, Jolles, J, van Os, J (2003). Alterations in theory of mind in patients with schizophrenia and non-psychotic relatives. Acta Psychiatrica Scandinavica 108, 110–117.CrossRefGoogle ScholarPubMed
Kapur, S, Mizrahi, R, Li, M (2005). From dopamine to salience to psychosis – linking biology, pharmacology and phenomenology of psychosis. Schizophrenia Research 79, 59–68.CrossRefGoogle ScholarPubMed
Kaymaz, N, van Os, J (2010). Extended psychosis phenotype – yes: single continuum – unlikely. Psychological Medicine. Published online: 20 March 2010. doi: 10.1017/S0033291710000358.CrossRefGoogle ScholarPubMed
Kramer, SE, Kapteyn, TS, Kuik, DJ, Deeg, DJ (2002). The association of hearing impairment and chronic diseases with psychosocial health status in older age. Journal of Aging and Health 14, 122–137.CrossRefGoogle ScholarPubMed
Lataster, T, Myin-Germeys, I, Derom, C, Thiery, E, van Os, J (2009). Evidence that self-reported psychotic experiences represent the transitory developmental expression of genetic liability to psychosis in the general population. American Journal of Medical Genetics Part B 150B, 1078–1084.CrossRefGoogle ScholarPubMed
Leask, SJ, Done, DJ, Crow, TJ (2002). Adult psychosis, common childhood infections and neurological soft signs in a national birth cohort. British Journal of Psychiatry 181, 387–392.CrossRefGoogle Scholar
Leff, JP (1968). Perceptual phenomena and personality in sensory deprivation. British Journal of Psychiatry 114, 1499–1508.CrossRefGoogle ScholarPubMed
Lieb, R, Isensee, B, von Sydow, K, Wittchen, HU (2000). The Early Developmental Stages of Psychopathology Study (EDSP): a methodological update. European Addiction Research 6, 170–182.CrossRefGoogle ScholarPubMed
Linscott, RJ, van Os, J (2010). Systematic reviews of categorical versus continuum models in psychosis: evidence for discontinuous subpopulations underlying a psychometric continuum. Implications for DSM-V, DSM-VI, and DSM-VII. Annual Review of Clinical Psychology 6, 391–419.CrossRefGoogle ScholarPubMed
Marschark, M (1993). Psychological Development of Deaf Children. Oxford University Press: New York.CrossRefGoogle Scholar
Mason, OJ, Brady, F (2009). The psychotomimetic effects of short-term sensory deprivation. Journal of Nervous and Mental Disease 197, 783–785.CrossRefGoogle ScholarPubMed
Olusanya, BO, Newton, VE (2007). Global burden of childhood hearing impairment and disease control priorities for developing countries. Lancet 369, 1314–1317.CrossRefGoogle ScholarPubMed
Paykel, ES, Abbott, R, Jenkins, R, Brugha, TS, Meltzer, H (2000). Urban–rural mental health differences in Great Britain: findings from the National Morbidity Survey. Psychological Medicine 30, 269–280.CrossRefGoogle ScholarPubMed
Peters, ER, Joseph, SA, Garety, PA (1999). Measurement of delusional ideation in the normal population: introducing the PDI (Peters et al. Delusions Inventory). Schizophrenia Bulletin 25, 553–576.CrossRefGoogle Scholar
Peterson, CC, Siegal, M (1995). Deafness, conversation and theory of mind. Journal of Child Psychology and Psychiatry 36, 459–474.CrossRefGoogle ScholarPubMed
Peterson, CC, Siegal, M (1998). Changing focus on the representational mind: deaf, autistic and normal children's concept of false photos, false drawings and false beliefs. British Journal of Developmental Psychology 16, 301–320.CrossRefGoogle Scholar
Peterson, CC, Wellman, HM, Liu, D (2005). Steps in theory-of-mind development for children with deafness or autism. Child Development 76, 502–517.CrossRefGoogle ScholarPubMed
Poulton, R, Caspi, A, Moffitt, TE, Cannon, M, Murray, R, Harrington, H (2000). Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study. Archives of General Psychiatry 57, 1053–1058.CrossRefGoogle ScholarPubMed
Reed, V, Gander, F, Pfister, H, Steiger, A, Sontagg, H, Trenkwalder, C, Hundt, W, Wittchen, H (1998). To what degree does the Composite International Diagnostic Interview (CIDI) correctly identify DSM-IV disorders? Testing validity issues in a clinical sample. International Journal of Methods in Psychiatric Research 7, 619–627.CrossRefGoogle Scholar
Romans-Clarkson, SE, Walton, VA, Herbison, GP, Mullen, PE (1990). Psychiatric morbidity among women in urban and rural New Zealand: psycho-social correlates. British Journal of Psychiatry 156, 84–91.CrossRefGoogle Scholar
Rossler, W, Riecher-Rossler, A, Angst, J, Murray, R, Gamma, A, Eich, D, van Os, J, Gross, VA (2007). Psychotic experiences in the general population: a twenty-year prospective community study. Schizophrenia Research 92, 1–14.CrossRefGoogle ScholarPubMed
Russell, PA, Hosie, JA, Gray, CD, Scott, C, Hunter, N, Banks, JS, Macaulay, MC (1998). The development of theory of mind in deaf children. Journal of Child Psychology and Psychiatry 39, 903–910.CrossRefGoogle ScholarPubMed
Schultz, G, Melzack, R (1991). The Charles Bonnet syndrome: ‘phantom visual images’. Perception 20, 809–825.CrossRefGoogle ScholarPubMed
Selten, JP, Cantor-Graae, E (2007). Hypothesis: social defeat is a risk factor for schizophrenia? British Journal of Psychiatry 51 (Suppl.), s9–s12.CrossRefGoogle ScholarPubMed
Sindhusake, D, Mitchell, P, Smith, W, Golding, M, Newall, P, Hartley, D, Rubin, G (2001). Validation of self-reported hearing loss. The Blue Mountains Hearing Study. International Journal of Epidemiology 30, 1371–1378.CrossRefGoogle ScholarPubMed
Spauwen, J, Krabbendam, L, Lieb, R, Wittchen, HU, van Os, J (2006). Evidence that the outcome of developmental expression of psychosis is worse for adolescents growing up in an urban environment. Psychological Medicine 36, 407–415.CrossRefGoogle Scholar
Stefanis, N, Thewissen, V, Bakoula, C, van Os, J, Myin-Germeys, I (2006). Hearing impairment and psychosis: a replication in a cohort of young adults. Schizophrenia Research 85, 266–272.CrossRefGoogle Scholar
Stein, LM, Thienhaus, OJ (1993). Hearing impairment and psychosis. International Psychogeriatrics 5, 49–56.CrossRefGoogle ScholarPubMed
Tharpe, AM, Sladen, DP (2008). Causation of permanent unilateral and mild bilateral hearing loss in children. Trends in Amplification 12, 17–25.CrossRefGoogle ScholarPubMed
Thewissen, V, Myin-Germeys, I, Bentall, R, de Graaf, R, Vollebergh, W, van Os, J (2005). Hearing impairment and psychosis revisited. Schizophrenia Research 76, 99–103.CrossRefGoogle ScholarPubMed
van der Werf, M, van Boxtel, M, Verhey, F, Jolles, J, Thewissen, V, van Os, J (2007). Mild hearing impairment and psychotic experiences in a normal aging population. Schizophrenia Research 94, 180–186.CrossRefGoogle Scholar
van Os, J, Linscott, RJ, Myin-Germeys, I, Delespaul, P, Krabbendam, L (2009). A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness–persistence–impairment model of psychotic disorder. Psychological Medicine 39, 179–195.CrossRefGoogle ScholarPubMed
van Os, J, Rutten, BP, Poulton, R (2008). Gene–environment interactions in schizophrenia: review of epidemiological findings and future directions. Schizophrenia Bulletin 34, 1066–1082.CrossRefGoogle ScholarPubMed
van Winkel, R, Stefanis, NC, Myin-Germeys, I (2008). Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene–stress interaction. Schizophrenia Bulletin 34, 1095–1105.CrossRefGoogle ScholarPubMed
Veling, W, Selten, JP, Susser, E, Laan, W, Mackenbach, JP, Hoek, HW (2007). Discrimination and the incidence of psychotic disorders among ethnic minorities in The Netherlands. International Journal of Epidemiology 36, 761–768.CrossRefGoogle ScholarPubMed
Verdoux, H, Maurice-Tison, S, Gay, B, Van Os, J, Salamon, R, Bourgeois, ML (1998). A survey of delusional ideation in primary-care patients. Psychological Medicine 28, 127–134.CrossRefGoogle ScholarPubMed
Weiser, M, Werbeloff, N, Drukker, M, Van Os, J, Dohrenwend, BP, Yoffe, R, Levav, I, Davidson, M (2009). Self-reported psychotic symptoms in the community, and risk of later hospitalization for non-affective psychotic disorders. Schizophrenia Bulletin 35, 74.Google Scholar
Welham, J, Scott, J, Williams, G, Najman, J, Bor, W, O'Callaghan, M, McGrath, J (2009). Emotional and behavioural antecedents of young adults who screen positive for non-affective psychosis: a 21-year birth cohort study. Psychological Medicine 39, 625–634.CrossRefGoogle ScholarPubMed
WHO (1990). Composite International Diagnostic Interview (CIDI), Version 1.0. World Health Organisation: Geneva, Switzerland.Google Scholar
Wittchen, H, Pfister, H (eds) (1997). DIA-X-Interviews: Manual für Screening-Verfahren und Interview; Interviewheft Längsschnittuntersuchung (DIA-X-Lifetime); Engänzungsheft (DIA-X-Lifetime); Interviewheft Querschnittsuntersuchung (DIA-X-Monatsversion); Ergänzungsheft (DIA-X-12 Monatsversion); PC-programm zur Durchfuhrung der Interviews (Längs und Querschnittsuntersuchung); Ausertungsprogramm [DIA-X-Interviews: Manual for Screening and Interview, Interview Issue Longitudinal Study (DIA-X-Lifetime), Supplement Issue (DIA-X-Lifetime); Interview Issue Cross-section Analysis (DIA-X-month version), Supplement Issue (DIA-X-12-month version), PC Program for Carrying out the Interviews (Longitudinal and Cross-examination); Analysis programme]. Swets & Zeiltinger: Frankfurt, Germany.Google Scholar
Wittchen, HU (1994). Reliability and validity studies of the WHO – Composite International Diagnostic Interview (CIDI): a critical review. Journal of Psychiatric Research 28, 57–84.CrossRefGoogle ScholarPubMed
Wittchen, HU, Lachner, G, Wunderlich, U, Pfister, H (1998 a). Test–retest reliability of the computerized DSM-IV version of the Munich-Composite International Diagnostic Interview (M-CIDI). Social Psychiatry and Psychiatric Epidemiology 33, 568–578.CrossRefGoogle ScholarPubMed
Wittchen, H-U, Lieb, R, Schuster, P, Oldehinkel, T (1999). When is onset? Investigations into early developmental stages of anxiety and depressive disorders. In Childhood Onset of ‘Adult’ Psychopathology, Clinical and Research Advances (ed. Rapoport, J. L.), pp. 259–302. American Psychiatric Press: Washington.Google Scholar
Wittchen, HU, Perkonigg, A, Lachner, G, Nelson, CB (1998 b). Early Developmental Stages of Psychopathology Study (EDSP): objectives and design. European Addiction Research 4, 18–27.CrossRefGoogle ScholarPubMed
Zammit, S, Odd, D, Horwood, J, Thompson, A, Thomas, K, Menezes, P, Gunnell, D, Hollis, C, Wolke, D, Lewis, G, Harrison, G (2009). Investigating whether adverse prenatal and perinatal events are associated with non-clinical psychotic symptoms at age 12 years in the ALSPAC birth cohort. Psychological Medicine 39, 1457–1467.CrossRefGoogle ScholarPubMed