Hostname: page-component-78c5997874-lj6df Total loading time: 0 Render date: 2024-11-09T05:46:30.715Z Has data issue: false hasContentIssue false
  • English
  • Français

Language and mathematical problems as precursors of psychotic-like experiences and juvenile mania symptoms

Published online by Cambridge University Press:  13 August 2013

M. Cederlöf ,
P. Östberg ,
E. Pettersson ,
H. Anckarsäter ,
C. Gumpert ,
S. Lundström  and
P. Lichtenstein
M. Cederlöf*
Affiliation:
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
P. Östberg
Affiliation:
Division of Speech and Language Pathology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
E. Pettersson
Affiliation:
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
H. Anckarsäter
Affiliation:
Department of Clinical Sciences, Forensic Psychiatry, Lund University, Sweden Institute of Neuroscience and Physiology, Forensic Psychiatry, University of Gothenburg, Sweden
C. Gumpert
Affiliation:
Section of Forensic Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
S. Lundström
Affiliation:
Centre for Ethics, Law and Mental Health (CELAM), University of Gothenburg, Sweden Gillberg Neuropsychiatry Centre, University of Gothenburg, Sweden
P. Lichtenstein
Affiliation:
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
*
*Address for correspondence: M. Cederlöf, M.Sc., Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE-171 77 Stockholm, Sweden. (Email: [email protected])
Get access Rights & Permissions [Opens in a new window]

Abstract

Background

Psychotic-like experiences (PLEs) and juvenile mania in adolescence index risk for severe psychopathology in adulthood. The importance of childhood problems with communication, reading, speech and mathematics for the development of PLEs and juvenile mania is not well understood.

Method

Through the Child and Adolescent Twin Study in Sweden, we identified 5812 children. The parents were interviewed about their children's development at age 9 or 12 years. At age 15 or 18 years, children and parents completed questionnaires targeting current PLEs and juvenile mania symptoms. Logistic regressions were used to assess associations between problems with communication, reading, speech and mathematics and PLEs/juvenile mania symptoms. To evaluate the relative importance of genes and environment in these associations, we used bivariate twin analyses based on structural equation models.

Results

Children with parent-endorsed childhood problems with communication, reading and mathematics had an increased risk of developing auditory hallucinations and parental-reported juvenile mania symptoms in adolescence. The most consistent finding was that children with childhood problems with communication, reading and mathematics had an increased risk of developing auditory hallucinations [for example, the risk for self-reported auditory hallucinations at age 15 was increased by 96% for children with communication problems: OR (odds ratio) 1.96, 95% confidence interval (CI) 1.33–2.88]. The twin analyses showed that genetic effects accounted for the increased risk of PLEs and juvenile mania symptoms among children with communication problems.

Conclusions

Childhood problems with communication, reading and mathematics predict PLEs and juvenile mania symptoms in adolescence. Similar to the case for schizophrenia and bipolar disorder, PLEs and juvenile mania may share genetic aetiological factors.

Keywords

Juvenile mania symptomslanguage problemsmathematical problemspsychotic-like experiences
Type
Original Articles
Information
Psychological Medicine , Volume 44 , Issue 6 , April 2014 , pp. 1293 - 1302
Copyright
Copyright © Cambridge University Press 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Anckarsäter, H, Lundström, S, Kollberg, L, Kerekes, N, Palm, C, Carlström, E, Långström, N, Magnusson, P, Halldner, L, Bölte, S, Gillberg, C, Gumpert, C, Råstam, M, Lichtenstein, P (2010). The Child and Adolescent Twin Study in Sweden (CATSS). Twin Research and Human Genetics 14, 495–508.Google Scholar
Bevan Jones, R, Thapar, A, Lewis, G, Zammit, S (2012). The association between early autistic traits and psychotic experiences in adolescence. Schizophrenia Research 135, 164–169.Google Scholar
Cannon, M, Caspi, A, Moffitt, TE, Harrington, H, Taylor, A, Murray, RM, Poulton, R (2002). Evidence for early-childhood, pan-developmental impairment specific to schizophreniform disorder. Archives of General Psychiatry 59, 449–456.Google Scholar
Chang, Z, Lichtenstein, P, Asherson, PJ, Larsson, H (2013). Developmental twin study of attention problems: high heritabilities throughout development. Journal of the American Medical Association Psychiatry 70, 311–318.Google Scholar
Crow, TJ, Done, DJ, Sacker, A (1995). Childhood precursors of psychosis as clues to its evolutionary origins. European Archives of Psychiatry and Clinical Neuroscience 245, 61–69.Google Scholar
Forsman, M, Långström, N (2012). Child maltreatment and adult violent offending: population-based twin study addressing the ‘cycle of violence’ hypothesis. Psychological Medicine 42, 1977–1983.Google Scholar
Hansson, SL, Svanström Röjvall, A, Råstam, M, Gillberg, C, Gillberg, IC, Anckarsäter, H (2005). Psychiatric telephone interview with parents for screening of childhood autism - tics, attention-deficit hyperactivity disorder and other comorbidities (A-TAC): preliminary reliability and validity. British Journal of Psychiatry 87, 262–267.Google Scholar
Henry, DB, Pavuluri, MN, Youngstrom, E, Birmaher, B (2008). Accuracy of brief and full forms of the Child Mania Rating Scale. Journal of Clinical Psychology 64, 368–381.Google Scholar
Hirschfeld, R, Williams, JBW, Spitzer, RL, Calabrese, JR, Flynn, L, Keck, PE, Lewis, L, McElroy, SL, Post, RM, Rapport, DJ, Russell, JM, Sachs, GS, Zajecka, J (2000). Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire. American Journal of Psychiatry 157, 1873–1875.CrossRefGoogle ScholarPubMed
Hollis, C (1995). Child and adolescent (juvenile onset) schizophrenia. A case-control study of premorbid developmental impairments. British Journal of Psychiatry 166, 489–495.Google Scholar
Janssen, I, Krabbendam, L, Bak, M, Hanssen, M, Volleberg, W, de Graaf, R, van Os, J (2004). Childhood abuse as a risk factor for psychotic experiences. Acta Psychiatrica Scandinavica 109, 38–45.Google Scholar
Kelleher, I, Harley, M, Murtagh, A, Cannon, M (2011). Are screening instruments valid for psychotic-like experiences? A validation study of screening questions for psychotic-like experiences using in-depth clinical interview. Schizophrenia Bulletin 37, 362–369.Google Scholar
Kelleher, I, Keeley, H, Corcoran, P, Lynch, F, Fitzpatrick, C, Devlin, N, Molloy, C, Clarke, MC, Harley, M, Arseneault, L, Wasserman, C, Carli, V, Hoven, C, Wasserman, D, Cannon, C (2012). Clinicopathological significance of psychotic experiences in non-psychotic young people: evidence from four population-based studies. British Journal of Psychiatry 201, 26–32.Google Scholar
Kolvin, I, Ounsted, C, Humphrey, M, McNay, A (1971). The phenomenology of childhood psychoses. British Journal of Psychiatry 118, 385–395.Google Scholar
Kutcher, S, Robertson, HA, Bird, D (1998). Premorbid functioning in adolescent onset bipolar I disorder: a preliminary report from an ongoing study. Journal of Affective Disorders 51, 137–144.Google Scholar
Larson, T, Anckarsäter, H, Gillberg, C, Ståhlberg, O, Carlström, E, Kadesjö, B, Råstam, M, Lichtenstein, P, Gillberg, C (2010). The Autism - Tics, AD/HD and other Comorbidities inventory (A-TAC): further validation of a telephone interview for epidemiological research. BMC Psychiatry 10, 1.CrossRefGoogle ScholarPubMed
Laurens, KR, Hodgins, S, Maughan, B, Murray, RM, Rutter, ML, Taylor, EA (2007). Community screening for psychotic-like experiences and other putative antecedents of schizophrenia in children aged 9–12 years. Schizophrenia Research 90, 130–146.Google Scholar
Lichtenstein, P, Yip, BH, Björk, C, Pawitan, Y, Cannon, TD, Sullivan, PF, Hultman, CM (2009). Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet 373, 234–239.Google Scholar
Murray, GK, Jones, PB (2012). Psychotic symptoms in young people without psychotic illness: mechanisms and meaning. British Journal of Psychiatry 201, 4–6.Google Scholar
Murray, RM, Sham, P, van Os, J, Zanelli, J, Cannon, M, McDonald, C (2004). A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophrenia Research 71, 405–416.Google Scholar
Muthén, LK, Muthén, BO (1998–2010). Mplus User's Guide, 6th edn. Muthén & Muthén: Los Angeles, CA.Google Scholar
Pavuluri, M, Birmaher, B, Naylor, MW (2005). Pediatric bipolar disorder: a review of the past 10 years. Journal of the American Academy of Child and Adolescent Psychiatry 44, 846–871.Google Scholar
Plomin, R, Asbury, K, Dip, PG, Dunn, J (2001). Why are children in the same family so different? Nonshared environment a decade later. Canadian Journal of Psychiatry 46, 225–233.Google Scholar
Polanczyk, G, Moffit, TE, Arseneault, L, Cannon, M, Ambler, M, Keefe, RSE, Houts, R, Odgers, CL, Caspi, A (2010). Etiological and clinical features of childhood psychotic symptoms: results from a birth cohort. Archives of General Psychiatry 67, 328–338.Google Scholar
Poulton, R, Caspi, A, Moffitt, TE, Cannon, M, Murray, R, Harrington, H (2000). Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study. Archives of General Psychiatry 57, 1053–1058.Google Scholar
Rijsdijk, FV, Sham, PC (2002). Analytic approaches to twin data using structural equation models. Briefings in Bioinformatics 3, 119–133.Google Scholar
Rössler, W, Vetter, S, Muller, M, Gallo, WT, Haker, H, Kawohl, W, Lupi, G, Ajdacic-Gross, V (2011). Risk factors at the low end of the psychosis continuum: much the same as at the upper end? Psychiatry Research 189, 77–81.Google Scholar
Rutter, M, Kim-Cohen, J, Maughan, B (2006). Continuities and discontinuities in psychopathology between childhood and adult life. Journal of Child Psychology and Psychiatry 47, 276–295.CrossRefGoogle ScholarPubMed
Sigurdson, E, Fombonne, E, Sayal, K, Checkley, S (1999). Neurodevelopmental antecedents of early-onset bipolar affective disorder. British Journal of Psychiatry 174, 121–127.Google Scholar
SAS Institute Inc. (2012). Base SAS® 9.3 Procedures Guide. SAS Institute Inc.: Cary, NC.Google Scholar
StataCorp (2011). Stata Statistical Software: Release 12. StataCorp LP: College Station, TX.Google Scholar
van Os, J, Jones, P, Lewis, G, Wadsworth, M, Murray, M (1997). Developmental precursors of affective illness in a general population birth cohort. Archives of General Psychiatry 54, 625–631.Google Scholar
van Os, J, Linscott, RJ, Myin-Germeys, I, Delespaul, P, Krabbendam, L (2009). A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness-persistence-impairment model of psychotic disorder. Psychological Medicine 39, 179–195.Google Scholar
Supplementary material: File

Cederlof Supplementary Materials

Table

Download Cederlof Supplementary Materials(File)
File 41.5 KB