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Hedonic capacity in schizophrenics and their twins

Published online by Cambridge University Press:  09 July 2009

Howard Berenbaum ,
Thomas F. Oltmanns  and
Irving I. Gottesman
Howard Berenbaum*
Affiliation:
Departments of Psychology, University of Illinois and University of Virginia, USA
Thomas F. Oltmanns
Affiliation:
Departments of Psychology, University of Illinois and University of Virginia, USA
Irving I. Gottesman
Affiliation:
Departments of Psychology, University of Illinois and University of Virginia, USA
*
1Address for correspondence: Dr Howard Berenbaum, Department of Psychology, 603 East Daniel Street, Champaign, IL 61820, USA.
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Synopsis

Audio-taped interviews recorded in the Gottesman–Shields schizophrenic twin series (17 pairs of identical twins, 14 pairs of fraternal same-sex twins, and 12 unpaired twins) were rated for level of hedonic capacity. Schizophrenics who were not hospitalized at the time of their interview were rated significantly lower (more impaired) on hedonic capacity than their normal co-twins. A significant negative correlation was also found between hedonic capacity and severity of illness. Hedonic capacity was found to be genetically influenced, although it appeared to be less heritable than the global diagnosis of schizophrenia. These results are consistent with Meehl's suggestion that reduced hedonic capacity is a heritable personality trait which potentiates the development of schizophrenia among those who are genetically predisposed to the disorder. The results suggest that anhedonia is not a phenotypic vulnerability marker for schizophrenia.

Type
Original Articles
Information
Psychological Medicine , Volume 20 , Issue 2 , May 1990 , pp. 367 - 374
Copyright
Copyright © Cambridge University Press 1990

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References

Berenbaum, H., Oltmanns, T. F. & Gottesman, I. I. (1985). Formal thought disorder in schizophrenics and their twins. Journal of Abnormal Psychology 94, 3–16.Google Scholar
Bleuler, E. (1950). Dementia Praecox or the Group of Schizophrenias (Translated by Zinkin, J..) International Universities Press: New York (Original work published 1911.)Google Scholar
Chapman, L. J. & Chapman, J. P. (1985). Psychosis proneness. In Controversies in Schizophrenia: Changes and Constancies (ed. Alpert, M.), pp. 157–174. Guilford: New York.Google Scholar
Chapman, L. J., Chapman, J. P. & Raulin, M. L. (1976). Scales for physical and social anhedonia. Journal of Abnormal Psychology 85, 374–382.Google Scholar
Dworkin, R. H. & Saczynski, K. (1984). Individual differences in hedonic capacity. Journal of Personality Assessment 48, 620–626.Google Scholar
Farmer, A. E., McGuffin, P. & Gottesman, I. I. (1987). Twin concordance for DSM-III schizophrenia: scrutinizing the validity of the definition. Archives of General Psychiatry 44, 634–641.Google Scholar
Fawcett, J., Clark, D. C., Scheftner, W. A. & Hedeker, D. (1983). Differences between anhedonic and normally hedonic depressive states. American Journal of Psychiatry 140, 1027–1030.Google Scholar
Gottesman, I. I. & Shields, J. (1972). Schizophrenia and Genetics: A Twin Study Vantage Point. Academic Press: New York.Google Scholar
Gottesman, I. I. & Shields, J. (1982). Schizophrenia: The Epigenetic Puzzle. Cambridge University Press: New York.Google Scholar
Hanson, D. R., Gottesman, I. I. & Heston, L. L. (1989). Long range schizophrenia forecasting: many a slip twixt cup and lip. In Risk and Protective Factors in the Development of Psychopathology (ed. Rolf, J., Neuchterlein, K., Masten, A. and Cicchetti, D.). Cambridge University Press: New York.Google Scholar
Holzman, P. S., Kringlen, E., Matthysse, S., Flanagan, S. D., Lipton, R. B., Cramer, G., Levin, S., Lange, K. & Levy, D. L. (1988). A single dominant gene can account for eye tracking dysfunctions and schizophrenia in offspring of discordant twins. Archives of General Psychiatry 45, 641–647.Google Scholar
Johnson, D. A. W. (1988). Drug treatment of schizophrenia. In Schizophrenia: The Major Issues (ed. Bebbington, P. and McGuffin, P.), pp. 158–171. Heinemann Professional Publishing: London.Google Scholar
Kendler, K. S. (1989). Limitations of the ratio of concordance rates in monozygotic and dizygotic twins. Archives of General Psychiatry 46, 477–478.Google Scholar
Knight, R. A. & Roff, J. D. (1985). Affectivity in schizophrenia. In Controversies in Schizophrenia: Changes and Constancies (ed. Alpert, M.), pp. 280–316. Guilford: New York.Google Scholar
Kraepelin, E. (1971). Dementia Praecox and Paraphrenia (Translated by Barclay, R. M.). Krieger Huntington: New York. (Original work published 1919.)Google Scholar
Kramer, M. S., Vogel, W. H., DiJohnson, C., Dewey, D. A., Sheves, P., Cavcchia, S., Litle, P., Schmidt, R. & Kimes, I. (1989). Antidepressants in ‘depressed’ schizophrenic inpatients. Archives of General Psychiatry 46, 922–928.CrossRefGoogle ScholarPubMed
McGue, M., Gottesman, I. I. & Rao, D. C. (1986). The analysis of schizophrenia family data. Behavior Genetics 16, 75–87.Google Scholar
McGuffin, P. (1984). Biological markers and psychosis. Psychological Medicine 14, 255–258.Google Scholar
McGuffin, P., Farmer, A. E., Gottesman, I. I., Murray, R. M. & Reveley, A. M. (1984). Twin concordance for operationally defined schizophrenia: confirmation of familiality and heritability. Archives of General Psychiatry 41, 541–545.Google Scholar
Meehl, P. E. (1962). Schizotaxia, schizotypy, schizophrenia. American Psychologist 17, 827–838.Google Scholar
Meehl, P. E. (1975). Hedonic capacity: some conjectures. Bulletin of the Menninger Clinic 39, 295–307.Google Scholar
Meehl, P. E. (1987). ‘Hedonic capacity’ ten years later: some clarifications. In Anhedonia and Affective Deficit Stales (ed. Clark, D. C. and Fawcett, J.), pp. 935–944. Pergamon: New York.Google Scholar
Meehl, P. E. (1989). Schizotaxia revisited. Archives of General Psychiatry 46, 935–944.CrossRefGoogle ScholarPubMed
Rado, S. (1956). Psychoanalysis of Behavior: Collected Papers (Vol. 1). Grune and Stratton: New York.Google Scholar
Rado, S. (1962). Psychoanalysis of Behavior: Collected Papers (Vol. 2). Grune and Stratton: New York.Google Scholar
Scheffé, H. (1959). The Analysis of Variance. Wiley: New York.Google Scholar
Tellegen, A., Lykken, D. T., Bouchard, T. J., Wilcox, K. J., Segal, N. L. & Rich, S. (1988). Personality similarity in twins reared apart and together. Journal of Personality and Social Psychology 54, 1031–1039.CrossRefGoogle ScholarPubMed
Zubin, J. & Spring, B. (1977). Vulnerability: a new view of schizophrenia. Journal of Abnormal Psychology 86, 103–126.CrossRefGoogle ScholarPubMed