Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-26T01:05:17.793Z Has data issue: false hasContentIssue false

Eighty-five per cent of what? Discrepancies in the weight cut-off for anorexia nervosa substantially affect the prevalence of underweight

Published online by Cambridge University Press:  08 September 2008

J. J. Thomas*
Affiliation:
Department of Psychology, Yale University, New Haven, CT, USA Klarman Eating Disorders Center, McLean Hospital, Harvard Medical School, MA, USA Eating Disorders Clinical and Research Program, Massachusetts General Hospital, Boston, MA, USA
C. A. Roberto
Affiliation:
Department of Psychology, Yale University, New Haven, CT, USA
K. D. Brownell
Affiliation:
Department of Psychology, Yale University, New Haven, CT, USA
*
*Address for correspondence: J. J. Thomas, Ph.D., Eating Disorders Clinical and Research Program, Massachusetts General Hospital, WAC-816D, 15 Parkman St, Boston, MA 02114, USA. (Email: [email protected])

Abstract

Background

DSM-IV cites <85% of expected body weight (EBW) as a guideline for the diagnosis of anorexia nervosa (AN) but does not require a specific method for calculating EBW. The purpose of the present study was to determine the degree to which weight cut-off calculations vary across studies, and to evaluate whether differential cut-offs lead to discrepancies in the prevalence of individuals who are eligible for the AN diagnosis.

Method

Two coders independently recorded the EBW calculation methods from 99 studies that either (a) compared individuals with AN to those with subclinical eating disorders or (b) conducted AN treatment trials. Each weight cut-off was applied to a nationally representative (n=12001) and treatment-seeking (n=189) sample to determine the impact of EBW calculation on the proportion who met the AN weight criterion.

Results

Coders identified 10 different EBW methods, each of which produced different weight cut-offs for the diagnosis of AN. Although only 0.23% of the national sample met the lowest cut-off, this number increased 43-fold to 10.10% under the highest cut-off. Similarly, only 48.1% of treatment seekers met the lowest cut-off, whereas 89.4% met the highest.

Conclusions

There is considerable variance across studies in the determination of the AN weight cut-off. Discrepancies substantially affect the proportion of individuals who are eligible for diagnosis, treatment and insurance reimbursement. However, differences may not be fully appreciated because the ubiquitous citation of the 85% criterion creates a sense of false consensus.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abbate-Daga, G, Piero, A, Gramaglia, C, Gandione, M, Fassino, S (2007). An attempt to understand the paradox of anorexia nervosa without drive for thinness. Psychiatry Research 149, 215221.Google Scholar
Andersen, AE, Bowers, WA, Watson, T (2001). A slimming program for eating disorders not otherwise specified. Psychiatric Clinics of North America 24, 19.Google Scholar
APA (2000). Diagnostic and Statistical Manual of Mental Disorders, 4th edn, revised. American Psychiatric Association: Washington, DC.Google Scholar
APA (2006). Practice Guideline for the Treatment of Patients with Eating Disorders, 3rd edn. American Psychiatric Association: Washington, DC.Google Scholar
Attia, E, Haiman, C, Walsh, BT, Flater, S (1998). Does fluoxetine augment the inpatient treatment of anorexia nervosa? American Journal of Psychiatry 155, 548551.Google Scholar
Bray, GA (1975). Obesity in Perspective. DHEW Publication No. 708. U.S. Government Printing Office: Washington, DC.Google Scholar
Bulik, CM, Berkman, ND, Brownley, KA, Sedway, JA, Lohr, KN (2007). Anorexia nervosa treatment: a systematic review of randomized controlled trials. International Journal of Eating Disorders 40, 310320.Google Scholar
Cachelin, FM, Maher, BA (1998). Is amenorrhea a critical criterion for anorexia nervosa? Journal of Psychosomatic Research 44, 435440.Google Scholar
Carlat, DJ, Camargo, CA, Herzog, DB (1997). Eating disorders in males: a report on 135 patients. American Journal of Psychiatry 154, 11271132.Google Scholar
CDC (2007). National Health and Nutrition Examination Survey Data. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention: Hyattsville, MD (www.cdc.gov/nchs/about/major/nhanes/datalink.htm). Accessed 18 February 2007.Google Scholar
Chiu, CH (1978). Standard weights for Chinese adults. Journal of the Chinese Nutrition Society (Taiwan) 3, 8594.Google Scholar
Clinton, D, Norring, C (1999). The rating of anorexia and bulimia (RAB) interview: development and preliminary validation. European Eating Disorders Review 7, 362371.Google Scholar
Dare, C, Eisler, I, Russell, G, Treasure, J, Dodge, L (2001). Psychological therapies for adults with anorexia nervosa: randomised controlled trial of out-patient treatments. British Journal of Psychiatry 178, 216221.Google Scholar
DHEW (1979). Weight by Height and Age for Adults 18–74 Years: United States 1971–1974. DHEW Publication No. 79-1656. Series 11, No. 280. Department of Health, Education, and Welfare: Rockville, MD.Google Scholar
Fairburn, CG, Cooper, Z, Doll, HA, Davies, BA (2005). Identifying dieters who will develop an eating disorder: a prospective, population-based study. American Journal of Psychiatry 162, 22492255.Google Scholar
Fullerton, DT, Wonderlich, SA, Gosnell, BA (1995). Clinical characteristics of eating disorder patients who report sexual or physical abuse. International Journal of Eating Disorders 17, 243249.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
Garkfinkel, PE, Lin, E, Goering, P, Spegg, C, Goldbloom, DS, Kennedy, S, Kaplan, AS, Woodside, DB (1996). Should amenorrhoea be necessary for the diagnosis of anorexia nervosa? Evidence from a Canadian community sample. British Journal of Psychiatry 168, 500506.Google Scholar
Gowers, S, Norton, K, Halek, C, Crisp, AH (1994). Outcome of outpatient psychotherapy in a random allocation treatment study of anorexia nervosa. International Journal of Eating Disorders 15, 165177.Google Scholar
Hebebrand, J, Himmelmann, GW, Heseker, H, Schafer, H, Remschmidt, H (1996). Use of percentiles for the body mass index in anorexia nervosa: diagnostic, epidemiological, and therapeutic considerations. International Journal of Eating Disorders 19, 359369.3.0.CO;2-K>CrossRefGoogle ScholarPubMed
Hedley, AA, Ogden, CL, Johnson, CL, Carroll, MD, Curtin, LR, Flegal, KM (2004). Prevalence of overweight and obesity among US children, adolescents, and adults, 1999–2002. Journal of the American Medical Association 291, 28472850.CrossRefGoogle ScholarPubMed
Howard, WT, Evans, K, Quintero-Howard, C, Bowers, WA, Andersen, A (1999). Predictors of success or failure of transition to day hospital treatment for inpatients with anorexia nervosa. American Journal of Psychiatry 156, 16971702.Google Scholar
Kaye, W, Toshihiko, N, Weltzin, T, Hsu, G, Sokol, M, McConaha, C, Plotnicov, K, Weise, J, Deep, D (2001). Double-blind placebo-controlled administration of fluoxetine in restricting- and restricting-purging-type anorexia nervosa. Biological Psychiatry 49, 644652.CrossRefGoogle ScholarPubMed
Klibanksi, A, Biller, B, Schoenfeld, D, Herzog, D, Saxe, V (1995). The effects of estrogen administration on trabecular bone loss in young women with anorexia nervosa. Journal of Clinical Endocrinology and Metabolism 80, 898904.Google Scholar
Kemsley, WFF (1951/2). Body weight at different ages and heights. Annals of Eugenics 16, 316334.Google Scholar
Keys, A (1977). Overweight and the risk of heart attack and sudden death. In Obesity in Perspective (ed. Bray, G.), DHEW Publication No. 708. U.S. Government Printing Office: Washington, DC.Google Scholar
Le Grange, D, Lock, J (2005). The dearth of psychological treatment studies for anorexia nervosa. International Journal of Eating Disorders 37, 7991.CrossRefGoogle ScholarPubMed
Lee, S, Chan, YY, Hsu, LK (2003). The intermediate-term outcome of Chinese patients with anorexia nervosa in Hong Kong. American Journal of Psychiatry 160, 967972.Google Scholar
Lee, S, Ho, TP, Hsu, LK (1993). Fat phobic and non-fat phobic anorexia nervosa: a comparative study of 70 Chinese patients in Hong Kong. Psychological Medicine 23, 9991017.CrossRefGoogle ScholarPubMed
Lee, S, Lee, AM, Ngai, E, Lee, DT, Wing, YK (2001). Rationales for food refusal in Chinese patients with anorexia nervosa. International Journal of Eating Disorders 29, 224229.Google Scholar
Levine, J, Gur, E, Loewenthal, R, Vishne, T, Dwolatzky, T, Van Beynum, IM, Sela, B-A, Vered, I, Yoseff, I, Stein, D (2007). Plasma homocysteine levels in female patients with eating disorders. International Journal of Eating Disorders 40, 277284.CrossRefGoogle ScholarPubMed
Lock, J, Le Grange, D, Agras, WS, Dare, C (2001). Treatment Manual for Anorexia Nervosa: A Family-based Approach. Guilford Press: New York.Google Scholar
McIntosh, V, Jordan, J, Carter, F, Luty, S, McKenzie, J, Bulik, C, Frampton, C, Joyce, P (2005). Three psychotherapies for anorexia nervosa: a randomized, controlled trial. American Journal of Psychiatry 162, 741747.Google Scholar
McIntosh, VVW, Jordan, J, Carter, FA, McKenzie, JM, Luty, SE, Bulik, CM, Joyce, PR (2004). Strict versus lenient weight criterion in anorexia nervosa. European Eating Disorders Review 12, 5160.Google Scholar
Metropolitan Life Insurance Company (1959). New weight standards for men and women. Statistical Bulletin 40, 14.Google Scholar
Metropolitan Life Insurance Company (1983). Metropolitan height and weight tables. Statistical Bulletin 64, 29.Google Scholar
Miller, K, Grieco, K, Klibanski, A (2005). Testosterone administration in women with anorexia nervosa. Journal of Clinical Endocrinology and Metabolism 90, 14281433.Google Scholar
Mitchell, JE, Cook-Myers, T, Wonderlich, SA (2005). Diagnostic criteria for anorexia nervosa: looking ahead to the DSM-V. International Journal of Eating Disorders 37, S95S97.CrossRefGoogle Scholar
Mizes, JS, Christiano, B, Madison, J, Post, G, Seime, R, Varnado, P (2000). Development of the Mizes Anorectic Cognitions Questionnaire-Revised: psychometric properties and factor structure in a large sample of eating disorder patients. International Journal of Eating Disorders 28, 415421.Google Scholar
Mizes, JS, Heffner, M, Madison, JK, Varnado-Sullivan, P (2004). The validity of subjective measures of body image disturbance. Eating Behaviors 5, 5566.CrossRefGoogle ScholarPubMed
NICE (2004). Eating Disorders – Core Interventions in the Treatment and Management of Anorexia Nervosa, Bulimia Nervosa and Related Eating Disorders. NICE Clinical Guideline No. 9. National Institute for Clinical Excellence (http://guidance.nice.org.uk/CG9/niceguidance/pdf/English). Accessed 24 March 2007.Google Scholar
Pike, KM, Walsh, BT, Vitousek, K, Wilson, GT, Bauer, J (2003). Cognitive behavior therapy in the posthospitalization treatment of anorexia nervosa. American Journal of Psychiatry 160, 20462049.Google Scholar
Peebles, R, Wilson, JL, Lock, JD (2006). How do children with eating disorders differ from adolescents with eating disorders at initial evaluation? Journal of Adolescent Health 39, 800805.Google Scholar
Powers, PS, Santana, CA, Bannon, YS (2002). Olanzapine in the treatment of anorexia nervosa: an open label trial. International Journal of Eating Disorders 32, 146154.Google Scholar
Roberto, CA, Steinglass, J, Mayer, LE, Attia, E, Walsh, BT (2008). The clinical significance of amenorrhea as a diagnostic criterion for anorexia nervosa. International Journal of Eating Disorders 41, 559563.Google Scholar
Schaefer, WK, Maclennan, RN, Yaholnitsky-Smith, SA, Stove, ED (1998). Psychometric evaluation of the eating disorder inventory (EDI) in a clinical group. Psychology and Health 13, 873881.Google Scholar
Schork, EJ, Eckert, ED, Halmi, K (1994). The relationship between psychopathology, eating disorder diagnosis, and clinical outcome at 10-year follow-up in anorexia nervosa. Comprehensive Psychiatry 35, 113123.Google Scholar
Solenberger, SE (2001). Exercise and eating disorders: a 3-year inpatient hospital record analysis. Eating Behaviors 2, 151168.CrossRefGoogle ScholarPubMed
Strokosch, GR, Friedman, AJ, Wu, S-C, Kamin, M (2006). Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in adolescent females with anorexia nervosa: a double-blind, placebo-controlled study. Journal of Adolescent Health 39, 819827.Google Scholar
Thaw, J, Williamson, D, Martin, C (2001). Impact of altering DSM-IV criteria for anorexia and bulimia nervosa on the base rates of eating disorder diagnoses. Eating and Weight Disorders 6, 121129.Google Scholar
Turner, H, Bryant-Waugh, R (2004). Eating disorder not otherwise specified (EDNOS): profiles of clients presenting at a community eating disorder service. European Eating Disorders Review 12, 1826.CrossRefGoogle Scholar
Vandereycken, W, Pieters, G (1992). A large-scale longitudinal follow-up study of patients with eating disorders: methodological issues and preliminary results. In The Course of Eating Disorders: Long-term Follow-up Studies of Anorexia and Bulimia Nervosa (ed. Herzog, W., Deter, H.-C. and Vandereycken, W.), pp. 182197. Springer-Verlag: New York.CrossRefGoogle Scholar
Walters, EE, Kendler, KS (1995). Anorexia nervosa and anorexia-like syndromes in a population-based female twin sample. American Journal of Psychiatry 152, 6471.Google Scholar
Watson, TL, Andersen, AE (2003). A critical examination of the amenorrhea and weight criteria for diagnosing anorexia nervosa. Acta Psychiatrica Scandinavica 108, 175182.Google Scholar
WHO (1992–1994). International Statistical Classification of Diseases and Related Health Problems, 10th edn. World Health Organization: Geneva.Google Scholar
Willett, WC, Dietz, WH, Colditz, GA (1999). Guidelines for a healthy weight. New England Journal of Medicine 341, 427434.CrossRefGoogle ScholarPubMed
Williamson, DA, Womble, LG, Smeets, MAM, Netemeyer, RG, Thaw, JM, Kutlesic, V, Gleaves, DH (2002). Latent structure of eating disorder symptoms: a factor analytic and taxometric investigation. American Journal of Psychiatry 159, 412418.Google Scholar