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Effect of lithium administration on RNA metabolism in rat brain

Published online by Cambridge University Press:  09 July 2009

A. J. Dewar  and
H. W. Reading
A. J. Dewar
Affiliation:
M.R.C. Brain Metabolism Unit, Department of Pharmacology, University of Edinburgh
H. W. Reading
Affiliation:
M.R.C. Brain Metabolism Unit, Department of Pharmacology, University of Edinburgh
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Synopsis

An attempt has been made to explain the changes in uric acid levels observed in the phase of manic depressive illness by suggesting that they may be a reflection of changes in brain RNA metabolism. The effect of prolonged lithium administration on RNA synthesis in rat brain and liver has been studied. Differences in the rate of turnover of brain RNA between the lithium-treated and saline control animals have been observed.

Type
Research Article
Information
Psychological Medicine , Volume 1 , Issue 3 , May 1971 , pp. 254 - 259
Copyright
Copyright © Cambridge University Press 1971

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References

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