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DSM outcomes of psychotic experiences and associated risk factors: 6-year follow-up study in a community-based sample

Published online by Cambridge University Press:  13 August 2018

Umut Kırlı Open the ORCID record for Umut Kırlı [Opens in a new window] ,
Tolga Binbay ,
Marjan Drukker ,
Hayriye Elbi ,
Bülent Kayahan ,
Duygu Keskin Gökçelli ,
Ferda Özkınay ,
Hüseyin Onay ,
Köksal Alptekin  and
Jim van Os
Umut Kırlı
Affiliation:
Education and Research Hospital, Van, Turkey Department of Psychiatry and Psychology, Maastricht University Medical Centre, School of Mental Health and Neuroscience, South Limburg Mental Health Research and Teaching Network, PO Box 616, Vijverdal 6200 MD, Maastricht, The Netherlands
Tolga Binbay*
Affiliation:
Faculty of Medicine, Department of Psychiatry, Dokuz Eylül University, 35340, Izmir, Turkey
Marjan Drukker
Affiliation:
Department of Psychiatry and Psychology, Maastricht University Medical Centre, School of Mental Health and Neuroscience, South Limburg Mental Health Research and Teaching Network, PO Box 616, Vijverdal 6200 MD, Maastricht, The Netherlands
Hayriye Elbi
Affiliation:
Faculty of Medicine, Department of Psychiatry, Ege University, 35140, Izmir, Turkey
Bülent Kayahan
Affiliation:
Faculty of Medicine, Department of Psychiatry, Ege University, 35140, Izmir, Turkey
Duygu Keskin Gökçelli
Affiliation:
Faculty of Medicine, Department of Psychiatry, Ege University, 35140, Izmir, Turkey
Ferda Özkınay
Affiliation:
Faculty of Medicine, Department of Medical Genetics, Ege University, 35140, Izmir, Turkey
Hüseyin Onay
Affiliation:
Faculty of Medicine, Department of Medical Genetics, Ege University, 35140, Izmir, Turkey
Köksal Alptekin
Affiliation:
Faculty of Medicine, Department of Psychiatry, Dokuz Eylül University, 35340, Izmir, Turkey
Jim van Os
Affiliation:
Department of Psychiatry and Psychology, Maastricht University Medical Centre, School of Mental Health and Neuroscience, South Limburg Mental Health Research and Teaching Network, PO Box 616, Vijverdal 6200 MD, Maastricht, The Netherlands Department of Psychosis Studies, King's College, King's Health Partners, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, UK Department of Psychiatry, Brain Centre Rudolf Magnus, Utrecht University Medical Centre, PO BOX 85500, 3508 GA Utrecht, The Netherlands
*
Author for correspondence: Tolga Binbay, E-mail: [email protected]
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Abstract

Background

Psychotic experiences (PEs) may predict a range of common, non-psychotic disorders as well as psychotic disorders. In this representative, general population-based cohort study, both psychotic and non-psychotic disorder outcomes of PE were analysed, as were potential moderators.

Methods

Addresses were contacted in a multistage clustered probability sampling frame covering 11 districts and 302 neighbourhoods at baseline (n = 4011). Participants were interviewed with the Composite International Diagnostic Interview (CIDI) both at baseline and at 6-year follow-up. Participants with PE at baseline were clinically re-interviewed with the SCID-I at follow-up. The role of socio-demographics, characteristics of PE, co-occurrence of mood disorders and family history of mental disorders were tested in the association between baseline PE and follow-up diagnosis.

Results

In the participants with baseline PE, the psychotic disorder diagnosis rate at follow up was 7.0% – much lower than the rates of DSM-IV mood disorders without psychotic features (42.8%) and other non-psychotic disorders (24.1%). Within the group with baseline PE, female sex, lower socio-economic status, co-occurrence of mood disorders, family history of a mental disorder and persistence of PE predicted any follow-up DSM diagnosis. Furthermore, onset of psychotic v. non-psychotic disorder was predicted by younger age (15–30 years), co-presence of delusional and hallucinatory PE and family history of severe mental illness.

Conclusion

The outcome of PE appears to be a consequence of baseline severity of multidimensional psychopathology and familial risk. It may be useful to consider PE as a risk indicator that has trans-diagnostic value.

Keywords

Community-based populationfamily history of mental disordersfollow-up studymood disordersnon-psychotic disorderspersistence of psychotic experiencespsychotic disorderspsychotic experiencessocio-demographic factorstype of psychotic experiences
Type
Original Articles
Information
Psychological Medicine , Volume 49 , Issue 8 , June 2019 , pp. 1346 - 1356
Copyright
Copyright © Cambridge University Press 2018 

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References

Addington, J, Cornblatt, BA, Cadenhead, KS, Cannon, TD, McGlashan, TH, Perkins, DO, Seidman, LJ, Tsuang, MT, Walker, EF, Woods, SW and Heinssen, R (2011) At clinical high risk for psychosis: outcome for nonconverters. The American Journal of Psychiatry 168, 800–805.Google Scholar
Alptekin, K, Ulas, H, Akdede, BB, Tumuklu, M and Akvardar, Y (2009) Prevalence and risk factors of psychotic symptoms: in the city of Izmir, Turkey. Social Psychiatry and Psychiatric Epidemiology 44, 905–910.Google Scholar
Andrews, G and Peters, L (1998) The psychometric properties of the Composite International Diagnostic Interview. Social Psychiatry and Psychiatric Epidemiology 33, 80–88.Google Scholar
Bhavsar, V, Maccabe, JH, Hatch, SL, Hotopf, M, Boydell, J and McGuire, P (2017) Subclinical psychotic experiences and subsequent contact with mental health services. BJPsych Open 3, 64–70.Google Scholar
Binbay, T, Elbi, H, Alptekin, K, Aksu Tanik, F, Drukker, M, Onay, H, Ozkinay, F, Zagli, N and Van Os, J (2011) Izmir mental health survey for gene-environment interaction in psychoses (TurkSch): objectives and methodology. Turk Psikiyatri Dergisi = Turkish Journal of Psychiatry 22, 65–76.Google Scholar
Binbay, T, Alptekin, K, Elbi, H, Zagli, N, Drukker, M, Aksu Tanik, F, Ozkinay, F, Onay, H and Van Os, J (2012 a) [Lifetime prevalence and correlates of schizophrenia and disorders with psychotic symptoms in the general population of Izmir, Turkey]. Turk Psikiyatri Dergisi = Turkish Journal of Psychiatry 23, 149–160.Google Scholar
Binbay, T, Drukker, M, Elbi, H, Tanik, FA, Ozkinay, F, Onay, H, Zagli, N, van Os, J and Alptekin, K (2012 b) Testing the psychosis continuum: differential impact of genetic and nongenetic risk factors and comorbid psychopathology across the entire spectrum of psychosis. Schizophrenia Bulletin 38, 992–1002.Google Scholar
Brugha, TS and Cragg, D (1990) The List of Threatening Experiences: the reliability and validity of a brief life events questionnaire. Acta Psychiatrica Scandinavica 82, 77–81.Google Scholar
Cannon, TD, Cadenhead, K, Cornblatt, B, Woods, SW, Addington, J, Walker, E, Seidman, LJ, Perkins, D, Tsuang, M, McGlashan, T and Heinssen, R (2008) Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Archives of General Psychiatry 65, 28–37.Google Scholar
Carrion, RE, McLaughlin, D, Goldberg, TE, Auther, AM, Olsen, RH, Olvet, DM, Correll, CU and Cornblatt, BA (2013) Prediction of functional outcome in individuals at clinical high risk for psychosis. JAMA Psychiatry 70, 1133–1142.Google Scholar
Castle, DJ, Wessely, S and Murray, RM (1993) Sex and schizophrenia: effects of diagnostic stringency, and associations with and premorbid variables. British Journal of Psychiatry 162, 658–664.Google Scholar
Chapman, LJ, Chapman, JP, Kwapil, TR, Eckblad, M and Zinser, MC (1994) Putatively psychosis-prone subjects 10 years later. Journal of Abnormal Psychology 103, 171–183.Google Scholar
Cilli, AS and Kaya, N (2003) [Nicotine dependence and psychiatric comorbidity among university students]. Turk Psikiyatri Dergisi = Turkish Journal of Psychiatry 14, 42–49.Google Scholar
Collip, D, Myin-Germeys, I and Van Os, J (2008) Does the concept of ‘sensitization’ provide a plausible mechanism for the putative link between the environment and schizophrenia? Schizophrenia Bulletin 34, 220–225.Google Scholar
Cooper, L, Peters, L and Andrews, G (1998) Validity of the Composite International Diagnostic Interview (CIDI) psychosis module in a psychiatric setting. Journal of Psychiatric Research 32, 361–368.Google Scholar
Cougnard, A, Marcelis, M, Myin-Germeys, I, De Graaf, R, Vollebergh, W, Krabbendam, L, Lieb, R, Wittchen, HU, Henquet, C, Spauwen, J and Van Os, J (2007) Does normal developmental expression of psychosis combine with environmental risk to cause persistence of psychosis? A psychosis proneness-persistence model. Psychological Medicine 37, 513–527.Google Scholar
De Loore, E, Gunther, N, Drukker, M, Feron, F, Sabbe, B, Deboutte, D, van Os, J and Myin-Germeys, I (2011) Persistence and outcome of auditory hallucinations in adolescence: a longitudinal general population study of 1800 individuals. Schizophrenia Research 127, 252–256.Google Scholar
Debbane, M, Eliez, S, Badoud, D, Conus, P, Fluckiger, R and Schultze-Lutter, F (2015) Developing psychosis and its risk states through the lens of schizotypy. Schizophrenia Bulletin 41(suppl. 2), S396–S407.Google Scholar
Deveci, A, Taskin, O, Dinc, G, Yilmaz, H, Demet, MM, Erbay-Dundar, P, Kaya, E and Ozmen, E (2007) Prevalence of pseudoneurologic conversion disorder in an urban community in Manisa, Turkey. Social Psychiatry and Psychiatric Epidemiology 42, 857–864.Google Scholar
Dhossche, D, Ferdinand, R, Van der Ende, J, Hofstra, MB and Verhulst, F (2002) Diagnostic outcome of self-reported hallucinations in a community sample of adolescents. Psychological Medicine 32, 619–627.Google Scholar
Dominguez, MD, Wichers, M, Lieb, R, Wittchen, HU and van Os, J (2011) Evidence that onset of clinical psychosis is an outcome of progressively more persistent subclinical psychotic experiences: an 8-year cohort study. Schizophrenia Bulletin 37, 84–93.Google Scholar
Dragt, S, Nieman, DH, Veltman, D, Becker, HE, van de Fliert, R, de Haan, L and Linszen, DH (2011) Environmental factors and social adjustment as predictors of a first psychosis in subjects at ultra high risk. Schizophrenia Research 125, 69–76.Google Scholar
Falkenberg, I, Valmaggia, L, Byrnes, M, Frascarelli, M, Jones, C, Rocchetti, M, Straube, B, Badger, S, McGuire, P and Fusar-Poli, P (2015) Why are help-seeking subjects at ultra-high risk for psychosis help-seeking? Psychiatry Research 228, 808–815.Google Scholar
Fatemi, SH and Folsom, TD (2009) The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophrenia Bulletin 35, 528–548.Google Scholar
Fisher, HL, Caspi, A, Poulton, R, Meier, MH, Houts, R, Harrington, H, Arseneault, L and Moffitt, TE (2013) Specificity of childhood psychotic symptoms for predicting schizophrenia by 38 years of age: a birth cohort study. Psychological Medicine 43, 2077–2086.Google Scholar
Fonseca Pedrero, E and Debbane, M (2017) Schizotypal traits and psychotic-like experiences during adolescence: an update. Psicothema 29, 5–17.Google Scholar
Fusar-Poli, P and Schultze-Lutter, F (2016) Predicting the onset of psychosis in patients at clinical high risk: practical guide to probabilistic prognostic reasoning. Evidence-Based Mental Health 19, 10–15.Google Scholar
Fusar-Poli, P, Bonoldi, I, Yung, AR, Borgwardt, S, Kempton, MJ, Valmaggia, L, Barale, F, Caverzasi, E and McGuire, P (2012) Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk. Archives of General Psychiatry 69, 220–229.Google Scholar
Fusar-Poli, P, Carpenter, WT, Woods, SW and McGlashan, TH (2014) Attenuated psychosis syndrome: ready for DSM-5.1? Annual Review of Clinical Psychology 10, 155–192.Google Scholar
Goldthorpe, J (1987) Social Mobility and Class Structure in Modern Britain. New York: Clarendon Press.Google Scholar
Guloksuz, S, van Nierop, M, Lieb, R, van Winkel, R, Wittchen, HU and van Os, J (2015) Evidence that the presence of psychosis in non-psychotic disorder is environment-dependent and mediated by severity of non-psychotic psychopathology. Psychological Medicine 45, 2389–2401.Google Scholar
Hanssen, M, Bak, M, Bijl, R, Vollebergh, W and van Os, J (2005) The incidence and outcome of subclinical psychotic experiences in the general population. The British Journal of Clinical Psychology 44, 181–191.Google Scholar
Honings, S, Drukker, M, van Nierop, M, van Winkel, R, Wittchen, HU, Lieb, R, Ten Have, M, de Graaf, R, van Dorsselaer, S and van Os, J (2016) Psychotic experiences and incident suicidal ideation and behaviour: disentangling the longitudinal associations from connected psychopathology. Psychiatry Research 245, 267–275.Google Scholar
Hyde, TM, Ziegler, JC and Weinberger, DR (1992) Psychiatric disturbances in metachromatic leukodystrophy. Insights into the neurobiology of psychosis. Archives of Neurology 49, 401–406.Google Scholar
Kaymaz, N, Drukker, M, Lieb, R, Wittchen, HU, Werbeloff, N, Weiser, M, Lataster, T and van Os, J (2012) Do subthreshold psychotic experiences predict clinical outcomes in unselected non-help-seeking population-based samples? A systematic review and meta-analysis, enriched with new results. Psychological Medicine 42, 2239–2253.Google Scholar
Kelleher, I, Harley, M, Murtagh, A and Cannon, M (2011) Are screening instruments valid for psychotic-like experiences? A validation study of screening questions for psychotic-like experiences using in-depth clinical interview. Schizophrenia Bulletin 37, 362–369.Google Scholar
Kelleher, I, Keeley, H, Corcoran, P, Lynch, F, Fitzpatrick, C, Devlin, N, Molloy, C, Roddy, S, Clarke, MC, Harley, M, Arseneault, L, Wasserman, C, Carli, V, Sarchiapone, M, Hoven, C, Wasserman, D and Cannon, M (2012) Clinicopathological significance of psychotic experiences in non-psychotic young people: evidence from four population-based studies. The British Journal of Psychiatry 201, 26–32.Google Scholar
Kelleher, I, Cederlof, M and Lichtenstein, P (2014) Psychotic experiences as a predictor of the natural course of suicidal ideation: a Swedish cohort study. World Psychiatry 13, 184–188.Google Scholar
Kelleher, I, Wigman, JT, Harley, M, O'Hanlon, E, Coughlan, H, Rawdon, C, Murphy, J, Power, E, Higgins, NM and Cannon, M (2015) Psychotic experiences in the population: association with functioning and mental distress. Schizophrenia Research 165, 9–14.Google Scholar
Kessler, RC, Chiu, WT, Demler, O, Merikangas, KR and Walters, EE (2005) Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Archives of General Psychiatry 62, 617–627.Google Scholar
Kish, L (1949) A procedure for objective respondent selection within the household. Journal of the American Statistical Association 44, 380–387.Google Scholar
Lin, A, Wood, SJ, Nelson, B, Beavan, A, McGorry, P and Yung, AR (2015) Outcomes of nontransitioned cases in a sample at ultra-high risk for psychosis. The American Journal of Psychiatry 172, 249–258.Google Scholar
Linscott, RJ and van Os, J (2013) An updated and conservative systematic review and meta-analysis of epidemiological evidence on psychotic experiences in children and adults: on the pathway from proneness to persistence to dimensional expression across mental disorders. Psychological Medicine 43, 1133–1149.Google Scholar
McGrath, JJ, Saha, S, Al-Hamzawi, A, Andrade, L, Benjet, C, Bromet, EJ, Browne, MO, Caldas de Almeida, JM, Chiu, WT, Demyttenaere, K, Fayyad, J, Florescu, S, de Girolamo, G, Gureje, O, Haro, JM, Ten Have, M, Hu, C, Kovess-Masfety, V, Lim, CC, Navarro-Mateu, F, Sampson, N, Posada-Villa, J, Kendler, KS and Kessler, RC (2016) The bidirectional associations between psychotic experiences and DSM-IV mental disorders. The American Journal of Psychiatry 173, 997–1006.Google Scholar
Mortensen, PB, Pedersen, MG and Pedersen, CB (2010) Psychiatric family history and schizophrenia risk in Denmark: which mental disorders are relevant? Psychological Medicine 40, 201–210.Google Scholar
Nelson, B, Yuen, HP, Wood, SJ, Lin, A, Spiliotacopoulos, D, Bruxner, A, Broussard, C, Simmons, M, Foley, DL, Brewer, WJ, Francey, SM, Amminger, GP, Thompson, A, McGorry, PD and Yung, AR (2013) Long-term follow-up of a group at ultra high risk (‘prodromal’) for psychosis: the PACE 400 study. JAMA Psychiatry 70, 793–802.Google Scholar
NIMH (1992) NIMH Genetics Initiative: Family Interview for Genetic Studies (FIGS). Rockville: MD National Institute of Mental Health.Google Scholar
Paus, T, Keshavan, M and Giedd, JN (2008) Why do many psychiatric disorders emerge during adolescence? Nature Reviews Neuroscience 9, 947–957.Google Scholar
Perlis, RH, Uher, R, Ostacher, M, Goldberg, JF, Trivedi, MH, Rush, AJ and Fava, M (2011) Association between bipolar spectrum features and treatment outcomes in outpatients with major depressive disorder. Archives of General Psychiatry 68, 351–360.Google Scholar
Poulton, R, Caspi, A, Moffitt, TE, Cannon, M, Murray, R and Harrington, H (2000) Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study. Archives of General Psychiatry 57, 1053–1058.Google Scholar
Rezaki, M, Ozgen, G, Kaplan, I, Gursoy, B, Sagduyu, A and Ozturk, O (1995) Results from Ankara center. In Ustun, TB and Sartorius, N (eds), Mental Illness in General Health Care: An International Study. Chichester: John Willey & Sons, pp. 39–56.Google Scholar
Robins, LN, Wing, J, Wittchen, HU, Helzer, JE, Babor, TF, Burke, J, Farmer, A, Jablenski, A, Pickens, R, Regier, DA, Sartorius, N and Towle, LH (1988) The Composite International Diagnostic Interview. An epidemiologic instrument suitable for use in conjunction with different diagnostic systems and in different cultures. Archives of General Psychiatry 45, 1069–1077.Google Scholar
Rossler, W, Hengartner, MP, Ajdacic-Gross, V, Haker, H, Gamma, A and Angst, J (2011) Sub-clinical psychosis symptoms in young adults are risk factors for subsequent common mental disorders. Schizophrenia Research 131, 18–23.Google Scholar
Salokangas, RK, Schultze-Lutter, F, Hietala, J, Heinimaa, M, From, T, Ilonen, T, Loyttyniemi, E, von Reventlow, HG, Juckel, G, Linszen, D, Dingemans, P, Birchwood, M, Patterson, P, Klosterkotter, J and Ruhrmann, S (2016) Depression predicts persistence of paranoia in clinical high-risk patients to psychosis: results of the EPOS project. Social Psychiatry and Psychiatric Epidemiology 51, 247–257.Google Scholar
Schmidt, SJ, Schultze-Lutter, F, Schimmelmann, BG, Maric, NP, Salokangas, RK, Riecher-Rossler, A, van der Gaag, M, Meneghelli, A, Nordentoft, M, Marshall, M, Morrison, A, Raballo, A, Klosterkotter, J and Ruhrmann, S (2015) EPA guidance on the early intervention in clinical high risk states of psychoses. European Psychiatry 30, 388–404.Google Scholar
Schultze-Lutter, F, Michel, C, Schmidt, SJ, Schimmelmann, BG, Maric, NP, Salokangas, RK, Riecher-Rossler, A, van der Gaag, M, Nordentoft, M, Raballo, A, Meneghelli, A, Marshall, M, Morrison, A, Ruhrmann, S and Klosterkotter, J (2015) EPA guidance on the early detection of clinical high risk states of psychoses. European Psychiatry 30, 405–416.Google Scholar
Shah, J, Eack, SM, Montrose, DM, Tandon, N, Miewald, JM, Prasad, KM and Keshavan, MS (2012) Multivariate prediction of emerging psychosis in adolescents at high risk for schizophrenia. Schizophrenia Research 141, 189–196.Google Scholar
Smeets, F, Lataster, T, van Winkel, R, de Graaf, R, Ten Have, M and van Os, J (2013) Testing the hypothesis that psychotic illness begins when subthreshold hallucinations combine with delusional ideation. Acta Psychiatrica Scandinavica 127, 34–47.Google Scholar
Smeets, F, Lataster, T, Viechtbauer, W and Delespaul, P (2015) Evidence that environmental and genetic risks for psychotic disorder may operate by impacting on connections between core symptoms of perceptual alteration and delusional ideation. Schizophrenia Bulletin 41, 687–697.Google Scholar
Spitzer, RL, Williams, JB, Gibbon, M and First, MB (1992) The Structured Clinical Interview for DSM-III-R (SCID). I: history, rationale, and description. Archives of General Psychiatry 49, 624–629.Google Scholar
Sullivan, SA, Wiles, N, Kounali, D, Lewis, G, Heron, J, Cannon, M, Mahedy, L, Jones, PB, Stochl, J and Zammit, S (2014) Longitudinal associations between adolescent psychotic experiences and depressive symptoms. PLoS ONE 9, e105758.Google Scholar
Topuzoglu, A, Binbay, T, Ulas, H, Elbi, H, Tanik, FA, Zagli, N and Alptekin, K (2015) The epidemiology of major depressive disorder and subthreshold depression in Izmir, Turkey: prevalence, socioeconomic differences, impairment and help-seeking. Journal of Affective Disorders 181, 78–86.Google Scholar
van Dam, DS, van Nierop, M, Viechtbauer, W, Velthorst, E, van Winkel, R, Bruggeman, R, Cahn, W, de Haan, L, Kahn, RS, Meijer, CJ, Myin-Germeys, I, van Os, J and Wiersma, D (2015) Childhood abuse and neglect in relation to the presence and persistence of psychotic and depressive symptomatology. Psychological Medicine 45, 1363–1377.Google Scholar
van Os, J and Guloksuz, S (2017) A critique of the ‘ultra-high risk’ and ‘transition’ paradigm. World Psychiatry 16, 200–206.Google Scholar
van Os, J and Reininghaus, U (2016) Psychosis as a transdiagnostic and extended phenotype in the general population. World Psychiatry 15, 118–124.Google Scholar
van Os, J, Hanssen, M, Bijl, RV and Ravelli, A (2000) Strauss (1969) revisited: a psychosis continuum in the general population? Schizophrenia Research 45, 11–20.Google Scholar
van Os, J, Linscott, RJ, Myin-Germeys, I, Delespaul, P and Krabbendam, L (2009) A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness-persistence-impairment model of psychotic disorder. Psychological Medicine 39, 179–195.Google Scholar
van Rossum, I, Dominguez, MD, Lieb, R, Wittchen, HU and van Os, J (2011) Affective dysregulation and reality distortion: a 10-year prospective study of their association and clinical relevance. Schizophrenia Bulletin 37, 561–571.Google Scholar
Verdoux, H and van Os, J (2002) Psychotic symptoms in non-clinical populations and the continuum of psychosis. Schizophrenia Research 54, 59–65.Google Scholar
Werbeloff, N, Drukker, M, Dohrenwend, BP, Levav, I, Yoffe, R, van Os, J, Davidson, M and Weiser, M (2012) Self-reported attenuated psychotic symptoms as forerunners of severe mental disorders later in life. Archives of General Psychiatry 69, 467–475.Google Scholar
Wigman, JT, van Nierop, M, Vollebergh, WA, Lieb, R, Beesdo-Baum, K, Wittchen, HU and van Os, J (2012) Evidence that psychotic symptoms are prevalent in disorders of anxiety and depression, impacting on illness onset, risk, and severity – implications for diagnosis and ultra-high risk research. Schizophrenia Bulletin 38, 247–257.Google Scholar
Wittchen, HU (1994) Reliability and validity studies of the WHO – Composite International Diagnostic Interview (CIDI): a critical review. Journal of Psychiatric Research 28, 57–84.Google Scholar
Wittchen, HU, Robins, LN, Cottler, LB, Sartorius, N, Burke, JD and Regier, D (1991) Cross-cultural feasibility, reliability and sources of variance of the Composite International Diagnostic Interview (CIDI). The Multicentre WHO/ADAMHA Field Trials. The British Journal of Psychiatry 159, 645–653, 658.Google Scholar
Yung, AR, Phillips, LJ, Yuen, HP, Francey, SM, McFarlane, CA, Hallgren, M and McGorry, PD (2003) Psychosis prediction: 12-month follow up of a high-risk (‘prodromal’) group. Schizophrenia Research 60, 21–32.Google Scholar
Zammit, S, Kounali, D, Cannon, M, David, AS, Gunnell, D, Heron, J, Jones, PB, Lewis, S, Sullivan, S, Wolke, D and Lewis, G (2013) Psychotic experiences and psychotic disorders at age 18 in relation to psychotic experiences at age 12 in a longitudinal population-based cohort study. The American Journal of Psychiatry 170, 742–750.Google Scholar
Zavos, HM, Eley, TC, McGuire, P, Plomin, R, Cardno, AG, Freeman, D and Ronald, A (2016) Shared etiology of psychotic experiences and depressive symptoms in adolescence: a longitudinal twin study. Schizophrenia Bulletin 42, 1197–1206.Google Scholar