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Down's syndrome and diabetes

Published online by Cambridge University Press:  09 July 2009

D. E. Jeremiah
Affiliation:
From the West Riding County Health Department, Wood Street, Wakefield
G. E. Leyshon
Affiliation:
From the West Riding County Health Department, Wood Street, Wakefield
Teresa Rose H. W. S. Francis
Affiliation:
From the West Riding County Health Department, Wood Street, Wakefield
R. W. Elliott
Affiliation:
From the West Riding County Health Department, Wood Street, Wakefield

Synopsis

A survey to determine the prevalence of diabetes in people with Down's syndrome was carried out at t raining centres in the West Riding of Yorkshire. Out of a total of 914 people known to the County Health Department as having this condition, 456 attended either junior or adult training centres and, of these, 404 provided urine specimens on two separate occasions. There were seven cases of diabetes among this group—a prevalence of 17 per thousand. Of more significance is the finding that the rate among children aged 0–14 years was 20·6 per thousand, which is considerably higher than expected in a population of this age group. It is postulated that there is an underlying defect of carbohydrate metabolism in people with Down's syndrome.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1973

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References

REFERENCES

Burch, P. R. J., and Milunsky, A. (1969). Early-onset diabetes mellitus in the general and Down's syndrome populations. Lancet, 1, 554558.CrossRefGoogle ScholarPubMed
College of General Practitioners. (1962). A Diabetes Survey. Report of a working party appointed by the College of General Practitioners. British Medical Jounral, 1, 14971503.CrossRefGoogle Scholar
Cone, T. R. Jr. (1954). Diabetes mellitus in a mongoloid. Journal of the Medical Society of New Jersey, 1, 6667.Google Scholar
Farquhar, J. W. (1969). Early-onset diabetes in the general and the Down's syndrome population. Lancet, 2, 323324.CrossRefGoogle ScholarPubMed
Harkness, J. (1962). Prevalence of glycosuria and diabetes mellitus. British Medical Journal, 1, 15031507.CrossRefGoogle ScholarPubMed
McDonald, G. W., and Fisher, G. F. (1967). Diabetes prevalence in the United States. Public Health Reports, 82, 334338.CrossRefGoogle ScholarPubMed
Milunsky, A., and Neurath, P. W. (1968). Diabetes mellitus in Down's syndrome. Archives of Environmental Health, 17, 372376.CrossRefGoogle ScholarPubMed
Penrose, L. S., and Smith, G. F. (1966). Down's Anomaly. Churchill: London.Google Scholar
Redhead, I. H. (1960). Incidence of glycosuria and diabetes mellitus in a general practice. British Medical Journal, 1, 695699.CrossRefGoogle ScholarPubMed
Rutter, M., Tizard, J., Whitmore, K. (eds.) (1970). Education, Health and Behaviour. Longman: London.Google Scholar
Sharp, C. L. (1964). Diabetes survey in Bedford 1962. Proceedings of the Royal Society of Medicine, 57, 193195.CrossRefGoogle ScholarPubMed
Sultz, H. A., Schlesinger, E. R., and Mosher, W. E. (1968). The Erie County survey of long-term childhood illness. 2. Incidence and prevalence. American Journal of Public Health, 58, 491498.CrossRefGoogle Scholar