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Depression and disability in Parkinson's disease: a follow-up of 132 cases

Published online by Cambridge University Press:  09 July 2009

R. G. Brown ,
B. Maccarthy ,
A.-M. Gotham ,
G. J. Der  and
C. D. Marsden
R. G. Brown*
Affiliation:
MRC Movement Disorder Research Group, University Department of Neurology and Parkinson's Disease Society Research Centre and MRC Social Psychiatry Unit, Institute of Psychiatry, London
B. Maccarthy
Affiliation:
MRC Movement Disorder Research Group, University Department of Neurology and Parkinson's Disease Society Research Centre and MRC Social Psychiatry Unit, Institute of Psychiatry, London
A.-M. Gotham
Affiliation:
MRC Movement Disorder Research Group, University Department of Neurology and Parkinson's Disease Society Research Centre and MRC Social Psychiatry Unit, Institute of Psychiatry, London
G. J. Der
Affiliation:
MRC Movement Disorder Research Group, University Department of Neurology and Parkinson's Disease Society Research Centre and MRC Social Psychiatry Unit, Institute of Psychiatry, London
C. D. Marsden
Affiliation:
MRC Movement Disorder Research Group, University Department of Neurology and Parkinson's Disease Society Research Centre and MRC Social Psychiatry Unit, Institute of Psychiatry, London
*
1Address for correspondence: Mr R. G. Brown, Department of Neurology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF.
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Synopsis

Patients with Parkinson's disease, 132 in number, were followed up after approximately one year, and measures of depression and disability re-administered. Depression was common on both occasions, and was characterized by dysphoria, pessimism and somatic symptoms, but not guilt or self-blame. Depression and disability were associated on both occasions. The relationship between changes in disability and depression across time was complex. In trying to understand changes in depression, the absolute change in disability may be less important than the relative change and rate of change. The results were discussed in relation to findings from other disease groups, and the implications for the clinical management of depression in Parkinson's disease.

Type
Research Article
Information
Psychological Medicine , Volume 18 , Issue 1 , February 1988 , pp. 49 - 55
Copyright
Copyright © Cambridge University Press 1988

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