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Comparative study of psychiatric patients with Klinefelter's syndrome and hypogonadism1

Published online by Cambridge University Press:  09 July 2009

A. Wakeling
A. Wakeling
Affiliation:
Academic Department of Psychiatry, Royal Free Hospital School of Medicine, London
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Synopsis

Eleven psychiatric patients with Klinefelter's syndrome are described and compared with nine patients in whom psychiatric illness was associated with hypogonadism due to causes other than chromosomal abnormality. The possible role of endocrine factors in the psychopathology of Klinefelter's syndrome is discussed in the light of the clinical and physical findings.

Type
Research Article
Information
Psychological Medicine , Volume 2 , Issue 2 , May 1972 , pp. 139 - 154
Copyright
Copyright © Cambridge University Press 1972

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References

REFERENCES

Becker, K. L., Hoffman, D. L., Albert, A., Underdahl, L. O., and Mason, H. L. (1966). Klinefelter's syndrome. Clinical and laboratory findings in 50 patients. Archives of Internal Medicine, 118, 314–321.CrossRefGoogle ScholarPubMed
Beaumont, P. J. V., Bancroft, J. H. J., Beardwood, C. L., and Russell, G. F. M. (1972). Behavioural changes following treatment with testosterone: case report. Psychological Medicine, 2, 70–72.CrossRefGoogle Scholar
Bleuler, M. (1954). Endokrinologische Psychiatrie. Thieme: Stuttgart.Google Scholar
Brooksbank, B. W. L., MacSweeney, D. A., Johnson, A. L., Cunningham, A. E., Wilson, D. A., and Coppen, A. (1970). Androgen excretion and physique in schizophrenia. British Journal of Psychiatry, 117, 413–420.CrossRefGoogle ScholarPubMed
Campbell, H. J. (1970a). The effect of steroid hormones on self-stimulation, central and peripheral. Steroidologia, 1, 8–24.Google ScholarPubMed
Campbell, H. J. (1970b). Control of the anterior pituitary gland by hypothalamic releasing-factors. In The Scientific Basis of Medicine Annual Reviews (1970), pp. 152–172. Athlone Press: London.Google Scholar
Ferguson-Smith, M. A. (1959). The prepubertal testicular lesion in chromatin-positive Klinefelter's syndrome (primary micro-orchidism) as seen in mentally handicapped children. Lancet, 1, 219–223.CrossRefGoogle ScholarPubMed
Goy, R. W. (1968). Organizing effects of androgen on the behaviour of rhesus monkeys. In Endocrinology and Human Behaviour, Proceedings of a conference, London, 1967, pp. 12–31. Edited by Michael, R. P.. Oxford University Press: London.Google Scholar
Hambert, G. (1964). Positive sex chromatin in men with epilepsy. Acta Medica Scandinavica, 175, 663–665.CrossRefGoogle ScholarPubMed
Hambert, G., and Frey, T. S. (1964). The electroencephalogram in the Klinefelter syndrome. Acta Psychiatrica Scandinavica, 40, 28–36.CrossRefGoogle ScholarPubMed
Hoaken, P. C. S., Clarke, M., and Breslin, M. (1964). Psychopathology in Klinefelter's syndrome. Psychosomatic Medicine, 26, 207–223.CrossRefGoogle ScholarPubMed
Huffer, V., Scott, W. H., Connor, T. B., and Lovice, H. (1964). Psychosexual studies of adult male patients with sexual infantilism before and after androgen therapy. Annals of Internal Medicine, 61, 255–268.CrossRefGoogle Scholar
Jacobs, P. A., and Strong, J. A. (1959). A case of human inter-sexuality having a possible XXY sex-determining mechanism. Nature, 183, 302–303.CrossRefGoogle Scholar
Kind, H. Th. (1967). Androgenic and oestrogenic hormones and human sexual behaviour. In An Introduction to Clinical Neuroendocrinology, pp. 368–379. Edited by Bajusz, E.. Karger: Basel.Google Scholar
Klinefelter, H. F. Jr., Reifenstein, E. C. Jr., and Albright, F. (1942). Syndrome sm characterized by gynecomastia, aspermatogenesis without A-leydigism, and increased excretion of follicle-stimulating hormone. Journal of Clinical Endocrinology and Metabolism, 2, 615–627.CrossRefGoogle Scholar
Kvale, J. N., and Fishman, J. R. (1965). The psychosocial aspects of Klinefelter's syndrome. Journal of the American Medical Association, 193, 567–572.CrossRefGoogle ScholarPubMed
Manthey, H. G. (1958). Psychological studies in cases of male gonadal insufficiency. Acta Endocrinologica (Kbh), 28, 213–218.Google Scholar
Money, J. (1963). Cytogenetic and psychosexual incongruities with a note on space-form blindness. American Journal of Psychiatry, 119, 820–827.CrossRefGoogle ScholarPubMed
Money, J., and Pollitt, E. (1964). Cytogenetic and psycho-sexual ambiguity: Klinefelter's syndrome and transvestism compared. Archives of General Psychiatry, 11, 589–595.CrossRefGoogle Scholar
SirMott, F. (1921). The psychopathology of puberty and adolescence. Journal of Mental Science, 67, 279–318.CrossRefGoogle Scholar
Myhre, S. A., Ruvalcaba, R. H. A., Johnson, H. R., Thuline, H. C., and Kelley, V. C. (1970). The effects of testosterone treatment in Klinefelter's syndrome. Journal of Pediatrics, 76, 267–276.CrossRefGoogle ScholarPubMed
Nielsen, J. (1969). Klinefelter's syndrome and the XYY syndrome. Acta Psychiatrica Scandinavica, Suppl. 209.Google Scholar
Nielsen, J., Sørensen, A., Theilgaard, A., Frøland, A., and Johnsen, S. G. (1969). A psychiatric–psychological study of 50 severely hypogonadal male patients, including 34 with Klinefelter's syndrome, 47, XXY. Acta Jutlandica, 41 (3), 183.Google Scholar
Pasqualini, R. Q., Vidal, G., and Bur, G. E. (1957). Psycho-pathology of Klinefelter's syndrome: a review of thirty-one cases. The Lancet, 2, 164–167.CrossRefGoogle Scholar
Polani, P. E. (1969). Abnormal sex chromosomes and mental disorders. Nature, 223, 680–686.CrossRefGoogle ScholarPubMed
Richter, D. (1970). The biological investigation of schizophrenia. Biological Psychiatry, 2, 153–164.Google ScholarPubMed
Shaw, D. J. (1967). Estimating WAIS IQ from progressive matrices scores. Journal of Clinical Psychology, 23, 184–185.3.0.CO;2-D>CrossRefGoogle ScholarPubMed
Swanson, D. W., and Stipes, A. H. (1969). Psychiatric aspects of Klinefelter's syndrome. American Journal of Psychiatry, 126, 814–822.CrossRefGoogle ScholarPubMed
Züblin, W. (1953). Zur Psychologie des Klinefelter-Syndroms. Acta Endocrinologica (Kbh), 14, 137–144.Google Scholar
Zuppinger, K., Engel, E., Forbes, A. P., Mantooth, L., and Claffey, J. (1967). Klinefelter's syndrome, a clinical and Cytogenetic study in twenty-four cases. Acta Endocrinologica (Kbh), suppl. 113, pp. 17, 27–33.Google Scholar