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Cognitive dysfunction in melancholia

Published online by Cambridge University Press:  09 July 2009

Richard Abrams*
Affiliation:
Department of Psychiatry and Behavioral Sciences, UHS/The Chicago Medical School, North Chicago, Illinois, USA
Michael Alan Taylor
Affiliation:
Department of Psychiatry and Behavioral Sciences, UHS/The Chicago Medical School, North Chicago, Illinois, USA
*
1Address for correspondence: Dr R. Abrams, Department of Psychiatry and Behavioral Sciences, UHS/The Chicago Medical School, 3333 Green Bay Road, North Chicago, Illinois 60064, USA

Synopsis

Sixty-seven patients with melancholia and 42 normal controls were tested with a battery of neuropsychological tasks selected to assess regional cortical functioning in both hemispheres. Compared with controls, melancholics exhibited a pattern of bifrontal and right parietal impairment, which was independent of age, sex, handedness and drug administration. These findings confirm and extend prior studies and contrast with those we and others have reported in patients with schizophrenia.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1987

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