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Biological component of the NIMH Clinical Research Branch Collaborative Program on the psychobiology of depression: II. Methodology and data analysis

Published online by Cambridge University Press:  09 July 2009

Steven Secunda ,
Stephen H. Koslow ,
D. Eugene Redmond ,
David Garver ,
T. Alan Ramsey ,
Jack Croughan ,
James Kocsis ,
Israel Hanin ,
Kenneth Lieberman  and
Regina Casper
Stephen H. Koslow
Affiliation:
Clinical Research Branch, National Institute of Mental Health, Rockville, Maryland, USA.
D. Eugene Redmond
Affiliation:
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
David Garver
Affiliation:
Department of Psychiatry, University of Cincinnati Medical Center, Cincinnati, Ohio, USA.
T. Alan Ramsey
Affiliation:
Veterans Administration Hospital, Philadelphia, Pennsylvania, USA.
Jack Croughan
Affiliation:
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA.
James Kocsis
Affiliation:
Payne Whitney Psychiatric Clinic, New York, New York, USA.
Israel Hanin
Affiliation:
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Kenneth Lieberman
Affiliation:
Psychoendocrine Study Unit, The New York Hospital, Cornell Medical Center, New York, New York, USA.
Regina Casper
Affiliation:
Illinois State Psychiatric Institute, Chicago, Illinois, USA.
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Synopsis

A preceding paper has reviewed the history, background, and rationale for this collaborative effort exploring the biologic basis of the affective disorders. This paper details the ‘flow’ of a subject through the experimental protocol, the instrumentation used to obtain the clinical and behavioural data, and the biologic methodologies employed in the analysis of the body fluids. Data management and analysis techniques developed for this study are also examined.

Type
Research Report
Information
Psychological Medicine , Volume 10 , Issue 4 , November 1980 , pp. 777 - 793
Copyright
Copyright © Cambridge University Press 1980

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