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Auditory hallucinations across the lifespan: a systematic review and meta-analysis

Published online by Cambridge University Press:  28 September 2017

K. Maijer ,
M. J. H. Begemann ,
S. J. M. C. Palmen ,
S. Leucht  and
I. E. C. Sommer
K. Maijer*
Affiliation:
Department of Psychiatry, University Medical Center Utrecht and Brain Center Rudolf Magnus, Heidelberglaan 100, 3485CX Utrecht, The Netherlands
M. J. H. Begemann
Affiliation:
Department of Psychiatry, University Medical Center Utrecht and Brain Center Rudolf Magnus, Heidelberglaan 100, 3485CX Utrecht, The Netherlands
S. J. M. C. Palmen
Affiliation:
Department of Psychiatry, University Medical Center Utrecht and Brain Center Rudolf Magnus, Heidelberglaan 100, 3485CX Utrecht, The Netherlands
S. Leucht
Affiliation:
Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Ismaningerstr. 22, 81675 München, Germany
I. E. C. Sommer
Affiliation:
Department of Psychiatry, University Medical Center Utrecht and Brain Center Rudolf Magnus, Heidelberglaan 100, 3485CX Utrecht, The Netherlands
*
*Address for correspondence: K. Maijer, M.D., Psychiatry Department, University Medical Center Utrecht, Brain Center Rudolf Magnus, HP A00.241, Heidelberglaan 100, 3485CX Utrecht, The Netherlands. (Email: [email protected])
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Abstract

Background

Auditory Hallucinations (AH) are nowadays regarded as symptoms following a continuum; from a (transient) phenomenon in healthy individuals on one end to a symptom of (psychiatric) illnesses at the other. An accumulating number of epidemiological studies focused on the prevalence of AH in the general population, but results vary widely. The current meta-analysis aims to synthesize existing evidence on lifetime prevalence of AH across the lifespan.

Methods

We conducted a quantitative review and meta-analysis according to PRISMA guidelines. Studies were combined to calculate a mean lifetime general population AH prevalence rate. Moreover, prevalences were calculated for four age groups: children (5–12 years), adolescents (13–17 years), adults (18–60 years) and elderly (⩾60 years).

Results

We retrieved 25 study samples including 84 711 participants. Mean lifetime prevalence rate of AH was 9.6% (95% CI 6.7–13.6%). The mean lifetime prevalence was similar in children (12.7%) and adolescents (12.4%), but these two groups differed significantly from the adults (5.8%) and the elderly (4.5%). Significant heterogeneity indicated that there is still dispersion in true prevalence rates between studies, even within the different age categories.

Conclusions

Current meta-analysis shows that AH are quite common (up to one in ten individuals) in the general population during lifetime, with children and adolescents reporting these experiences significantly more often compared with adults and elderly. Large follow-up studies on the longitudinal course of AH are needed to reveal associated risk and resilience factors.

Keywords

Adolescentsadultsauditory hallucinationschildrenepidemiologygeneral populationprevalence
Type
Invited Review
Information
Psychological Medicine , Volume 48 , Issue 6 , April 2018 , pp. 879 - 888
Copyright
Copyright © Cambridge University Press 2017 

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Footnotes

†

Both authors contributed equally to this work.

References

Aas, M, Dazzan, P, Mondelli, V, Melle, I, Murray, RM, Pariante, CM (2014). A systematic review of cognitive function in first-episode psychosis, including a discussion on childhood trauma, stress, and inflammation. Frontiers in Psychiatry 4, 182.CrossRefGoogle Scholar
Adriaanse, M, van Domburgh, L, Hoek, HW, Susser, E, Doreleijers, TA, Veling, W (2015). Prevalence, impact and cultural context of psychotic experiences among ethnic minority youth. Psychological Medicine 45, 637–646.CrossRefGoogle ScholarPubMed
Alsawy, S, Wood, L, Taylor, PJ, Morrison, AP (2015). Psychotic experiences and PTSD: exploring associations in a population survey. Psychological Medicine 45, 2849–2859.CrossRefGoogle Scholar
Barragan, M, Laurens, KR, Navarro, JB, Obiols, JE (2011). ‘Theory of Mind’, psychotic-like experiences and psychometric schizotypy in adolescents from the general population. Psychiatry Research 30;186, 225–231.CrossRefGoogle Scholar
Bartels-Velthuis, AA, Jenner, JA, Van de Willige, G, van Os, J, Wiersma, D (2010). Prevalence and correlates of auditory vocal hallucinations in middle childhood. British Journal of Psychiatry 196, 41–46.CrossRefGoogle ScholarPubMed
Beavan, V, Read, J, Cartwright, C (2011). The prevalence of voice-hearers in the general population: a literature review. Journal of Mental Health 20, 281–292.CrossRefGoogle ScholarPubMed
Begemann, MJH, Daalman, K, Heringa, SM, Schutte, MJ, Sommer, IE (2016). Childhood trauma as a risk factor for psychosis: the confounding role of cognitive functioning. Psychological Medicine 46, 1115–1118.CrossRefGoogle ScholarPubMed
Borenstein, M, Hedges, L, Higgins, J, Rothstein, H (2005). Comprehensive Meta-Analysis Version 2. Biostat Inc: Engelwood, NJ.Google Scholar
Borenstein, M, Hedges, L, Higgins, J, Rothstein, H (2009). Introduction to Meta-Analysis. Wiley: Chichester.CrossRefGoogle Scholar
Cederlöf, M, Ostberg, P, Pettersson, E, Anckarsäter, H (2014). Language and mathematical problems as precursors of psychotic-like experiences and juvenile mania symptoms. Psychological Medicine 44, 1293–1302.CrossRefGoogle ScholarPubMed
Daalman, K, Diederen, KM, Derks, EM, van Lutterveld, R, Kahn, RS, Sommer, IE (2012). Childhood trauma and auditory verbal hallucinations. Psychological Medicine 42, 2475–2484.CrossRefGoogle ScholarPubMed
De Leede-Smith, S, Barkus, E (2013). A comprehensive review of auditory verbal hallucinations: lifetime prevalence, correlates and mechanisms in healthy and clinical individuals. Frontiers in Human Neuroscience 7, 367.CrossRefGoogle ScholarPubMed
De Loore, E, Gunther, N, Drukker, M, Feron, F, Sabbe, B, Deboutte, D, van Os, J, Myin-Germeys, I (2011). Persistence and outcome of auditory hallucinations in adolescence: a longitudinal general population study of 1800 individuals. Schizophrenia Research 127, 252–256.CrossRefGoogle ScholarPubMed
Dolphin, L, Dooley, B, Fitzgerald, A (2015). Prevalence and correlates of psychotic like experiences in a nationally representative community sample of adolescents in Ireland. Schizophrenia Research 169, 241–247.CrossRefGoogle Scholar
Eaton, WW, Romanoski, A, Anthony, JC, Nestadt, G (1991). Screening for psychosis in the general population with a self-report interview. Journal of Nervous and Mental Disease 179, 689–693.CrossRefGoogle ScholarPubMed
Gogtay, N, Giedd, JN, Lusk, L, Hayashi, KM, Greenstein, D, Vaituzis, AC, Nugent, TF III, Herman, DH, Clasen, LS, Toga, AW, Rapoport, JL, Thompson, PM (2004). Dynamic mapping of human cortical development during childhood through early adulthood. Proceedings of the National Academy of Sciences of the United States of America 101, 8174–8179.CrossRefGoogle ScholarPubMed
Jardri, R, Bartels-Velthuis, AA, Debbané, M, Jenner, JA, Kelleher, I, Dauvilliers, Y, Plazzi, G, Demeulemeester, M, David, CN, Rapoport, J, Dobbelaere, D, Escher, S, Fernyhough, C (2014). From phenomenology to neurophysiological understanding of hallucinations in children and adolescents. Schizophrenia Bulletin 40(Suppl. 4), S221–S232.CrossRefGoogle ScholarPubMed
Johns, LC, Van Os, J (2001). The continuity of psychotic experiences in the general population. Clinical Psychological Review 21, 1125–1141.CrossRefGoogle ScholarPubMed
Kelleher, I, Cannon, M (2011). Psychotic-like experiences in the general population: characterizing a high-risk group for psychosis. Psychological Medicine 41, 1–6.CrossRefGoogle Scholar
Kelleher, I, Connor, D, Clarke, MC, Devlin, N, Harley, M, Cannon, M (2012 a) Prevalence of psychotic symptoms in childhood and adolescence: a systematic review and meta-analysis of population-based studies. Psychological Medicine 42, 1857–1863.CrossRefGoogle ScholarPubMed
Kelleher, I, Keeley, H, Corcoran, P, Lynch, F, Fitzpatrick, C, Devlin, N, Molloy, C, Roddy, S, Clarke, MC, Harley, M, Arseneault, L, Wasserman, C, Carli, V, Sarchiapone, M, Hoven, C, Wasserman, D, Cannon, M (2012 b) Clinicopathological significance of psychotic experiences in non-psychotic young people: evidence from four population-based studies. British Journal of Psychiatry 201, 26–32.CrossRefGoogle ScholarPubMed
Kessler, RC, Birnbaum, H, Demler, O, Falloon, IR, Gagnon, E, Guyer, M, Howes, MJ, Kendler, KS, Shi, L, Walters, E, Wu, EQ (2005). The prevalence and correlates of nonaffective psychosis in the National Comorbidity Survey Replication (NCS-R). Biological Psychiatry 58, 668–676.CrossRefGoogle ScholarPubMed
Knobel, KA, Lima, MC (2012). Are parents aware of their children's hearing complaints? Brazilian Journal of Otorhinolaryngology 78, 27–37.CrossRefGoogle ScholarPubMed
Kompus, K, Løberg, EM, Posserud, MB, Lundervold, AJ (2015). Prevalence of auditory hallucinations in Norwegian adolescents: results from a population-based study. Scandinavian Journal of Psychology 56, 391–396.CrossRefGoogle ScholarPubMed
Kråkvik, B, Larøi, F, Kalhovde, AM, Hugdahl, K, Kompus, K, Salvesen, Ø, Stiles, TC, Vedul-Kjelsås, E (2015). Prevalence of auditory verbal hallucinations in a general population: a group comparison study. Scandinavian Journal of Psychology 56, 508–515.CrossRefGoogle Scholar
Larøi, F (2012). How do auditory verbal hallucinations in patients differ from those in non-patients? Frontiers in Human Neuroscience 21, 6–25.Google Scholar
Lataster, T, van Os, J, Drukker, M, Henquet, C, Feron, F, Gunther, N, Myin-Germeys, I (2006). Childhood victimisation and developmental expression of non-clinical delusional ideation and hallucinatory experiences: victimisation and non-clinical psychotic experiences. Social Psychiatry and Psychiatric Epidemiology 41, 423–428.CrossRefGoogle ScholarPubMed
Laurens, KR, Hobbs, MJ, Sunderland, M, Green, MJ, Mould, GL (2012). Psychotic-like experiences in a community sample of 8000 children aged 9 to 11 years: an item response theory analysis. Psychological Medicine 42, 1495–1506.CrossRefGoogle Scholar
Linscott, RJ, van Os, J (2013). An updated and conservative systematic review and meta-analysis of epidemiological evidence on psychotic experiences in children and adults: on the pathway from proneness to persistence to dimensional expression across mental disorders. Psychological Medicine 43, 1133–1149.CrossRefGoogle ScholarPubMed
Mamah, D, Mbwayo, A, Mutiso, V, Barch, DM, Constantino, JN, Nsofor, T, Khasakhala, L, Ndetei, DM (2012). A survey of psychosis risk symptoms in Kenya. Comprehensive Psychiatry 53, 516–524.CrossRefGoogle ScholarPubMed
Mamah, D, Owoso, A, Mbwayo, AW, Mutiso, VN, Muriungi, SK, Khasakhala, LI, Barch, DM, Ndetei, DM (2013). Classes of psychotic experiences in Kenyan children and adolescents. Child Psychiatry and Human Development 44, 452–459.CrossRefGoogle ScholarPubMed
McGrath, JJ, Saha, S, Al-Hamzawi, A, Alonso, J, Bromet, EJ, Bruffaerts, R, Caldas-de-Almeida, JM, Chiu, WT, de Jonge, P, Fayyad, J, Florescu, S, Gureje, O, Haro, JM, Hu, C, Kovess-Masfety, V, Lepine, JP, Lim, CC, Mora, ME, Navarro-Mateu, F, Ochoa, S, Sampson, N, Scott, K, Viana, MC, Kessler, RC (2015). Psychotic experiences in the general population: a cross-national analysis based on 31,261 respondents from 18 countries. JAMA Psychiatry 72, 697–705.CrossRefGoogle Scholar
Moher, D, Liberati, A, Tetzlaff, J, Altman, DG (2009). PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 339, b2535.CrossRefGoogle ScholarPubMed
Nakazawa, N, Imamura, A, Nishida, A, Iwanaga, R, Kinoshita, H, Okazaki, Y, Ozawa, H (2011). Psychotic-like experiences and poor metal health status among Japanse early teens. Acta Medica Nagasakiensia 56, 35–41.Google Scholar
Pearson, D, Smalley, M, Ainsworth, C, Cook, M, Boyle, J, Flury, S (2008). Auditory hallucinations in adolescent and adult students: implications for continuums and adult pathology following child abuse. Journal of Nervous and Mental Disease 196, 634–638.CrossRefGoogle ScholarPubMed
Polanczyk, G, Moffitt, TE, Arseneault, L, Cannon, M, Ambler, A, Keefe, RS, Houts, R, Odgers, CL, Caspi, A (2010). Etiological and clinical features of childhood psychotic symptoms: results from a birth cohort. Archives of General Psychiatry 67, 328–338.CrossRefGoogle ScholarPubMed
Rubio, JM, Sanjuán, J, Flórez-Salamanca, L, Cuesta, MJ (2012). Examining the course of hallucinatory experiences in children and adolescents: a systematic review. Schizophrenia Research 138, 248–254.CrossRefGoogle ScholarPubMed
Schimmelmann, BG, Michel, C, Martz-Irngartinger, A, Linder, C, Schultze-Lutter, F (2015). Age matters in the prevalence and clinical significance of ultra-high-risk for psychosis symptoms and criteria in the general population: findings from the BEAR and BEARS-kid studies. World Psychiatry 14, 189–197.CrossRefGoogle ScholarPubMed
Scott, J, Welham, J, Martin, G, Bor, W, Najman, J, O'Callaghan, M, Williams, G, Aird, R, McGrath, J (2008). Demographic correlates of psychotic-like experiences in young Australian adults. Acta Psychiatrica Scandinavica 118, 230–237.CrossRefGoogle ScholarPubMed
Sharifi, V, Eaton, WW, Wu, LT, Roth, KB, Burchett, BM, Mojtabai, R (2015). Psychotic experiences and risk of death in the general population: 24–27 year follow-up of the Epidemiologic Catchment Area study. British Journal of Psychiatry 207, 30–36.CrossRefGoogle ScholarPubMed
Shevlin, M, Dorahy, MJ, Adamson, G (2007). Trauma and psychosis: an analysis of the National Comorbidity Survey. American Journal of Psychiatry 164, 166–169.CrossRefGoogle ScholarPubMed
Shevlin, M, Murphy, J, Read, J, Mallett, J, Adamson, G, Houston, JE (2011). Childhood adversity and hallucinations: a community-based study using the National Comorbidity Survey Replication. Social Psychiatry and Psychiatric Epidemiology 46, 1203–1210.CrossRefGoogle ScholarPubMed
Soares, WB, Ribeiz, SR, Bassitt, DP, De Oliveira, MC, Bottino, CM (2015). Psychotic symptoms in older people without dementia from a Brazilian community-based sample. International Journal of Geriatric Psychiatry 30, 437–445.CrossRefGoogle ScholarPubMed
Sommer, IE, Daalman, K, Rietkerk, T, Diederen, KM, Bakker, S, Wijkstra, J, Boks, MP (2010 a). Healthy individuals with auditory verbal hallucinations; who are they? Psychiatric assessments of a selected sample of 103 subjects. Schizophrenia Bulletin 36, 633–641.CrossRefGoogle ScholarPubMed
Sommer, IE, Derwort, AM, Daalman, K, de Weijer, AD, Liddle, PF, Boks, MP (2010 b). Formal thought disorder in non-clinical individuals with auditory verbal hallucinations. Schizophrenia Research 118, 140–145.CrossRefGoogle ScholarPubMed
Tien, AY (1991). Distributions of hallucinations in the population. Social Psychiatry and Psychiatric Epidemiology 26, 287–292.CrossRefGoogle ScholarPubMed
Toga, AW, Thompson, PM, Sowell, ER (2006). Mapping brain maturation. Trends in Neurosciences 29, 148–159.CrossRefGoogle ScholarPubMed
Van Lutterveld, R, Van den Heuvel, MP, Diederen, KMJ, de Weijer, AD, Begemann, MJ, Brouwer, RM, Daalman, K, Blom, JD, Kahn, RS, Sommer, IE (2014). Cortical thickness in individuals with nonclinical and clinical psychotic symptoms. Brain 137, 2664–2669.CrossRefGoogle ScholarPubMed
van Os, J, Linscott, RJ, Myin-Germeys, I, Delespaul, P, Krabbendam, L (2009). A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness persistence-impairment model of psychotic disorder. Psychological Medicine 39, 179–195.CrossRefGoogle Scholar
Verdoux, H, van Os, J, Maurice-Tison, S, Gay, B, Salamon, R, Bourgeois, M (1998). Is early adulthood a critical developmental stage for psychosis proneness? A survey of delusional ideation in normal subjects. Schizophrenia Research 29, 247–254.CrossRefGoogle ScholarPubMed
Wigman, JT, Vollebergh, WA, Raaijmakers, QA, Iedema, J, van Dorsselaer, S, Ormel, J, Verhulst, FC, van Os, J (2011). The structure of the extended psychosis phenotype in early adolescence–a cross-sample replication. Schizophrenia Bulletin 37, 850–860.CrossRefGoogle ScholarPubMed
Yoshizumi, T, Murase, S, Honjo, S, Kaneko, H, Murakami, T (2004). Hallucinatory experiences in a community sample of Japanese children. Journal of the American Academy of Child and Adolescent Psychiatry 43, 1030–1036.CrossRefGoogle Scholar
Yung, AR, Nelson, B, Baker, K, Buckby, JA, Baksheev, G, Cosgrave, EM (2009). Psychotic-like experiences in a community sample of adolescents: implications for the continuum model of psychosis and prediction of schizophrenia. Australian and New Zealand Journal of Psychiatry 43, 118–128.CrossRefGoogle Scholar