Hostname: page-component-5cf477f64f-fcbfl Total loading time: 0 Render date: 2025-04-01T05:30:30.105Z Has data issue: false hasContentIssue false
  • English
  • Français

The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies

Published online by Cambridge University Press:  03 May 2005

STEPHEN V. FARAONE ,
JOSEPH BIEDERMAN  and
ERIC MICK
STEPHEN V. FARAONE
Affiliation:
Medical Genetics Research Program and Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA
JOSEPH BIEDERMAN
Affiliation:
Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA
ERIC MICK
Affiliation:
Pediatric Psychopharmacology Unit of the Child Psychiatry Service, Massachusetts General Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA
Get access Rights & Permissions [Opens in a new window]

Abstract

Background. This study examined the persistence of attention deficit hyperactivity disorder (ADHD) into adulthood.

Method. We analyzed data from published follow-up studies of ADHD. To be included in the analysis, these additional studies had to meet the following criteria: the study included a control group and it was clear from the methods if the diagnosis of ADHD included subjects who did not meet full criteria but showed residual and impairing signs of the disorder. We used a meta-analysis regression model to separately assess the syndromatic and symptomatic persistence of ADHD.

Results. When we define only those meeting full criteria for ADHD as having ‘persistent ADHD’, the rate of persistence is low, ~15% at age 25 years. But when we include cases consistent with DSM-IV's definition of ADHD in partial remission, the rate of persistence is much higher, ~65%.

Conclusions. Our results show that estimates of ADHD's persistence rely heavily on how one defines persistence. Yet, regardless of definition, our analyses show that evidence for ADHD lessens with age. More work is needed to determine if this reflects true remission of ADHD symptoms or is due to the developmental insensitivity of diagnostic criteria for the disorder.

Type
Review Article
Information
Psychological Medicine , Volume 36 , Issue 2 , February 2006 , pp. 159 - 165
Copyright
2005 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)