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How to appraise an article on therapy

Published online by Cambridge University Press:  02 January 2018

James P. Warner*
Affiliation:
Royal Free Hospital School of Medicine, Rowland Hill Street, London NW3 2QG
Robert Blizard
Affiliation:
Royal Free Hospital School of Medicine, Rowland Hill Street, London NW3 2QG
*
Correspondence
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Abstract

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This first of a series of articles intended to guide clinicians through the evidence-based process assesses the published evidence for drug therapy in Alzheimer's disease. A Medline search identified a randomised, controlled trial of donepezil. Although this trial appeared to have a reasonably sound methodology, we had some doubts about the treatment effect and applicability of the results.

Type
Evidence-based psychiatry
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © 1998 The Royal College of Psychiatrists

References

Folstein, M. F., Folstein, S. E. & McHugh, P. R. (1975) ‘Mini Mental State.’ A practical method for grading the cognitive state of subjects for the clinics. Journal of Psychiatric Research 12, 189198.Google Scholar
Guy, W. (1976) ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: NIMH.Google Scholar
Geddes, J. R. & Harrison, P. J. (1997) Closing the gap between research and practice. British Journal of Psychiatry, 171, 220225.Google Scholar
Gilbody, S. (1996) Evidence-based medicine. An improved format for journal clubs. Psychiatric Bulletin, 20, 673675.Google Scholar
Goldner, E. M. & Bilsker, D. (1995) Evidence-based psychiatry. Canadian Journal of Psychiatry, 40, 97101.Google Scholar
Greenhalgh, T. (1997) How to read a paper – the medline database. British Medical Journal 315, 180183.Google Scholar
Rogers, S. L., Friedhoff, L. T. & The Donepezil Study Group (1996) The safety and efficacy of donepezil in patients with Alzheimer's disease: results of a US multicentre, randomised, double-blind, placebo-controlled trial. Dementia, 7, 293303.Google Scholar
Rosen, W. G., Mohs, R. C. & Davis, K. L. (1984) A new rating scale for Alzheimer's disease. American Journal of Psychiatry, 141, 13561364.Google Scholar
Sackett, D. L., Richardson, W. S., Rosenberg, W., et al (1997) Evidence-Based Medicine. New York: Churchill Livingstone.Google Scholar
Warner, J. P. & King, M. B. (1997) Evidence-based medicine and the journal club: a cross-sectional survey of participants' views. Psychiatric Bulletin, 21, 532534.Google Scholar
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