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Progress in Neurotherapeutics and Neuropsychopharmacology 2008

Published online by Cambridge University Press:  16 January 2008

Jeffrey L. Cummings
Jeffrey L. Cummings
Affiliation:
Departments of Neurology and Psychiatry and Behavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Email: [email protected]
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Extract

ABSTRACT

There has been continuous progress in neurotherapeutics and neuropsychopharmacology in the past year. Notable are the reports of successful preliminary disease-modifying trials in Niemann-Pick disease and Friedreich's ataxia. Progress also has been made in treatment of migraine, stroke, epilepsy, multiple sclerosis, traumatic brain injury, and pain. Biomarkers are increasingly used to establish proof of pharmacology including measures of cerebrospinal fluid constituents and brain changes on magnetic resonance imaging. There is an increasing diversity of patient populations participating in clinical trials, including pediatric migraine and traumatic brain injury.

Keywords

argatrobanatorvastatinbiomarkersbipolar depressionclinical trialsdeep brain stimulationdepressiondisease modificationduloxatineepilepsyfingolimodFriedreich's ataxiaglatiramer acetateHuntington's diseaseIdebenonemethylphenidatemiglustatmigrainemodafinilmultiple sclerosisneuropathic painnicardipineNiemann-Pick Type C diseaseParkinson's diseasepharmacogeneticspregabalinretigabinriluzoleritogitinerivastigminerizatripanschizophreniaspinal cord injury paintestosteronetramiprosatetranscranial magnetic stimulationtraumatic brain injuryzolmitriptanzonisamide.
Type
Research Article
Information
Progress in Neurotherapeutics and Neuropsychopharmacology , Volume 3 , Issue 1 , January 2008 , pp. 1 - 11
Copyright
© 2008 Cambridge University Press

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