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IX.—The Influence of Gelatin on the Stability of a Colloidal Solution of Cholesterol, and on the Charge on the Particles

Published online by Cambridge University Press:  15 September 2014

William Ogilvy Kermack
Affiliation:
Research Laboratory of the Royal College of Physicians, Edinburgh, and the Pathological Department of the Royal Infirmary of Edinburgh
Peter MacCallum
Affiliation:
Research Laboratory of the Royal College of Physicians, Edinburgh, and the Pathological Department of the Royal Infirmary of Edinburgh
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Summary

1. The properties of a colloidal sol of cholesterol have been investigated, more particularly in relation to the effect of pH in the presence of protein (gelatin) of various concentrations.

2. The cataphoretic P.D. between the particles of the sol and the medium has been determined in the presence of gelatin at various concentrations and at various pH values.

3. The effect of the presence of gelatin in preventing the precipitation of a cholesterol sol by sodium chloride at various pH values has been investigated. It has been shown that the amount of gelatin required to protect is approximately that required to cover the particles with a layer of gelatin from one to two atoms thick.

4. The mechanisms of precipitation and protection are discussed in the light of these results.

Type
Proceedings
Copyright
Copyright © Royal Society of Edinburgh 1926

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References

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