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VI.—Genetics of Gametes. VI. Attempted Genetic Transformation in the Rabbit*

Published online by Cambridge University Press:  11 June 2012

R. A. Beatty
Affiliation:
Agricultural Research Council Unit of Animal Genetics, Institute of Animal Genetics, Edinburgh
F. S. Billett
Affiliation:
Department of Zoology, University College, London
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Synopsis

Genetic transformation in the rabbit has been attempted by the artificial insemination of semen incubated with deoxyribonucleic acid. No evidence was obtained of any transformation at the albino or rex loci, nor of sex. The experiments comprised twenty inseminated does, and 133 offspring of several categories.

Type
Research Article
Copyright
Copyright © Royal Society of Edinburgh 1961

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References

References to Literature

Austin, C. R., 1960. “Fate of Spermatozoa in the Female Generative Tract”, J. Reprod. Fertil., 1, 151156.CrossRefGoogle Scholar
Bearn, J. G., and Kirby, K. S., 1959. “Failure of Deoxyribonucleic Acid to Produce Pigment Changes in the Albino Rat”, Exp. Cell Res., 17, 547549.CrossRefGoogle ScholarPubMed
Benoit, J., Leroy, P., Vendrely, C., and Vendrely, R., 1957. “Des Mutations Somatiques dirigées, sont-elles possibles chez les Oiseaux?”, C.R. Acad. Set., Paris, 244, 23202321.Google Scholar
Benoit, J., Leroy, P., Vendrely, C., and Vendrely, R., 1957. “Modifications de caractères raciaux observées sur les canetons issus de carnes et de canards Pékin préablement soumis à des injections d'acide désoxyribonucléique de Canard Khaki”, C.R. Acad. Set., Paris, 245, 448451.Google Scholar
Benoit, J., Leroy, P., Vendrely, C., and Vendrely, R. 1959. “Phénotype actuel des canard Pékin traités en 1956 à l'acide désoxyribonucleique de Canard Khaki Campbell et de leurs descendants”, C.R. Acad. Sci., Paris, 248, 26462648.Google Scholar
Cox, R. A., Overend, W. G., Peacocke, A. R., and Wilson, S., 1958. “The Action of γ Rays on Sodiumdeoxyribonucleate in Solution”, Proc. Roy. Soc. Lond., B, 149, 511533.Google ScholarPubMed
Marko, A. M., and Butler, G. C., 1951. “The Isolation of Sodium-deoxyribonucleate with Sodium Dodecyl Sulphate”, J. Biol. Chem., 190, 165176.CrossRefGoogle Scholar
Sevag, M. G., Lackman, D. B., and Smolens, J., 1938. “The Isolation of the Components of Streptococcal Nucleoprotein in Serologically Active Form”, J. Biol. Chem., 124, 425436.Google Scholar
Zamenhof, S., Alexander, H. E., and Leidy, G., 1953. “Studies on the Chemistry of the Transforming Activity”, J. Exp. Med., 98, 373397.CrossRefGoogle ScholarPubMed
Walton, A., 1945. Notes on The Technique of Artificial Insemination. The Holborn Surgical Instrument Co., London.Google Scholar