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The Biochemical Effects of Ionizing Irradiation on Nuclear Function in Animal Cells

Published online by Cambridge University Press:  11 June 2012

Margery G. Ord  and
L. A. Stocken
Margery G. Ord
Affiliation:
Department of Biochemistry, University of Oxford.
L. A. Stocken
Affiliation:
Department of Biochemistry, University of Oxford.
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Extract

This discussion of the biochemical lesions produced in animal cells by ionizing radiation will to all intents and purposes be restricted to a consideration of the immediate response to doses of 1000 rads or less in two rat tissues only, namely the thymus gland and the regenerating liver. The experiments we have carried out with these two tissues have led us to the view that in these organs the ultimate damage to the cell stems from an initial upset of the nuclear thiol-disulphide equilibrium.

Type
Research Article
Information
Proceedings of the Royal Society of Edinburgh, Section B: Biological Sciences , Volume 70 , Issue 2 , 1968 , pp. 117 - 124
Copyright
Copyright © Royal Society of Edinburgh 1968

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References

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