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V.—Principles of Effective and Safe Transfusion

Published online by Cambridge University Press:  05 December 2011

John D. Cash
John D. Cash
Affiliation:
Deputy Director, Edinburgh and South-East Scotland Blood Transfusion Service
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Extract

If the organisers of this Symposium had invited our colleagues in the pharmaceutical industry to outline their concepts of efficiency, it is probable that two quite separate areas of endeavour would have emerged. In the first place, emphasis would have been made of efficiency in terms of technology, use of manpower and the production of profitable and useful by-products. In the second place, as the result of clinical trials, the persuasive Clinical Advisors would define the type of patient likely to benefit from their preparations, the correct dosage and the possibility of untoward effects. It is these broad aspects of effectiveness and safety which I wish to discuss in relation to blood transfusion, set against the fundamental question: what we are doing with our raw material at the present time and what awaits us in the future?

Type
Research Article
Information
Proceedings of the Royal Society of Edinburgh, Section B: Biological Sciences , Volume 71 , supplement S1 , 1972 , pp. s47 - s57
Copyright
Copyright © Royal Society of Edinburgh 1972

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References

References to Literature

ad hoc Committee, 1971. Morbidity and Mortality, 20, 123.Google Scholar
Ashley, A., 1954. New Engl. Med., 250, 412.CrossRefGoogle Scholar
Blumberg, B. S., Alter, H. J. and Visnich, S., 1965. J. Am. Med. Ass., 191, 545.Google Scholar
Blumberg, B. S., Gerstley, B. J. S. and Hungerford, D. A., 1967. Ann. Intern. Med., 66, 924.CrossRefGoogle Scholar
Blumberg, B. S., Sutnick, A. L. and London, W. T., 1968. Bull. N.Y. Acad. Med., 44, 1566.Google Scholar
Brinkhous, K. M., Shanbrom, E., Roberts, N. R., Webster, W. P. and Wagner, R. H., 1968. J. Am. Med. Ass. 205, 67.CrossRefGoogle Scholar
Bruce White, G. B., Lasheen, R. M., Baillie, M. B. and Turner, G. C., 1971. J. Clin. Path., 24, 8.CrossRefGoogle Scholar
Cash, J. D., 1969. Hazards of Therapy, p. 72. (Ed. Robertson, F. R..) Edinburgh: Roy. Coll. Physicians.Google Scholar
Chaplin, H., 1969. New Engl. J. Med., 281, 364.CrossRefGoogle Scholar
Cullingford, B. T., 1964. Nature, Lond., 201, 1092.CrossRefGoogle Scholar
Das, P. C., 1972. Personal Communication.Google Scholar
Gardiner, A. J. S. and Dudley, H. A. F., 1963. Lancet, 2, 859.CrossRefGoogle Scholar
Gerin, J. L., Holland, P. V. and Purcell, R. H., 1971. J. Virol., 7, 569.CrossRefGoogle Scholar
Giles, J. P., Mccollum, R. W. and Berndtson, L. W., 1969. New Engl. J. Med., 281, 119.CrossRefGoogle Scholar
Gocke, D. J., 1970. Vox Sang., 19, 327.CrossRefGoogle Scholar
Gocke, D. J., Greenberg, H. B. and Kavey, N. B., 1970. J. Am. Med. Ass., 212, 877.CrossRefGoogle Scholar
Gollup, S., Svigalo, R., Bailey, C. P., Hirose, R. and Schaefer, C., 1971. J. Am. Med. Ass., 215, 2077.CrossRefGoogle Scholar
Greenwalt, T. J., 1969. Vox Sang., 16, 247.CrossRefGoogle Scholar
Gutteridge, B. H. and Shaw, A. E., 1971. Aust. & N. Z. J. Med., 1, 1325.CrossRefGoogle Scholar
Hiercholzer, W. J. and Le Bouvier, G. L., 1969. Quoted by Le Bouvier and McCollum, 1970.Google Scholar
Hirschman, R. J., Itscoitz, S. B. and Shulman, N. R., 1970. Blood, 35, 189.CrossRefGoogle Scholar
Jenson, A. B., Mccombs, R. M., Sakurada, N. and Melnick, J. L., 1970. Exp. Molec. Path., 13, 217.CrossRefGoogle Scholar
Johnson, A. J., Karpatkin, M. H. and Newman, J., 1970. Biblthca Haemat., 34, 30.Google Scholar
Jozwiak, W., Koscielak, J. and Madalinski, K., 1971. Nature, Lond., 229, 92.Google Scholar
Kasper, C. K., Dietrich, S. L. and Rapaport, S. I., 1970. Archs Int. Med. 125, 1004.CrossRefGoogle Scholar
Kistler, P., 1972. Vox Sang, (in press).Google Scholar
Koff, R. S. and Isselbacher, K. J., 1968. New Engl. J. Med., 278, 1371.CrossRefGoogle Scholar
Kohn, J. and Morgan, J. R., 1971. J. Clin. Path., 24, 673.CrossRefGoogle Scholar
Krugman, S., 1963. New Engl. J. Med., 269, 195.CrossRefGoogle Scholar
Le Bouvier, G. L. and Mccollum, R. W., 1970. Adv. Virus Res. 16, 357.CrossRefGoogle Scholar
Levene, C. and Blumberg, B. S., 1969. Nature, Lond., 221, 195.CrossRefGoogle Scholar
Lundsguaard-Hansen, P., 1969. Biblthca Haemat., 33, 9.Google Scholar
Millman, I., Zavarone, V., Gerstley, B. J. S. and Blumberg, B. S., 1969. Nature, Lond., 222, 5189.CrossRefGoogle Scholar
Morrow, A. G. and Chanock, R. N., 1969. J. Infect. Dis., 120, 383.Google Scholar
Morton, J. H., 1969. Surgery, 65, 407.Google Scholar
National Communicable Disease Centre, 1968. Morbidity and Mortality, 17, 290.Google Scholar
Ockochi, K. and Murakami, S., 1968. Vox Sang., 15, 374.CrossRefGoogle Scholar
Ockochi, K., Murakami, S. and Ninomiya, K., 1970. Vox Sang., 18, 289.CrossRefGoogle Scholar
Otto-Servais, M., Plomteux, G., Brocteur, J., Buret, J., Lennes, G., Andre, A. and Henoghem, , 1970. Vox Sang., 19, 338.CrossRefGoogle Scholar
Paine, R. S. and Janeway, C. A., 1952. J. Am. Med. Ass., 150, 199.CrossRefGoogle Scholar
Pollock, T. M. and Reid, D., 1969. Lancet, 1, 281.CrossRefGoogle Scholar
Prince, A. M., 1970. Am. J. Trap. Med. Hyg., 19, 872.CrossRefGoogle Scholar
Prince, A. M., 1970. Vox Sang., 19, 417.Google Scholar
Prince, A. M., 1968. Proc. Natn. Acad. Sci., U.S.A., 60, 814.CrossRefGoogle Scholar
Public Health Laboratory Service, 1968. Br. Med. J., 3, 451.CrossRefGoogle Scholar
Purcell, R. H., Holland, P. V., Walsh, J. R. and Wong, D. C., 1969. J. Infect. Dis. 121, 222.CrossRefGoogle Scholar
Raunio, V. K., London, W. T., Sutnick, A. I., Millman, I. and Blumberg, B. S., 1970. Proc. Soc. Exp. Biol. Med., 134, 548.CrossRefGoogle Scholar
Registrar General's Statistical Review of England and Wales, 1967, 1971. Commentary. London: H.M.S.O.Google Scholar
Rizza, C. R. and Biggs, R., 1969. In Recent Advances in Blood Coagulation, p. 179. (Ed. Poller, L..). London: Churchill.Google Scholar
Robboy, S. J., Lewis, E. J., Schur, P. H. and Colman, R. W., 1970. Am. J. Med., 49, 742.CrossRefGoogle Scholar
Rush, B. J. and Stewart, R. A., 1969. New Engl. J. Med., 280, 1202.CrossRefGoogle Scholar
Shirley, J. A., Grove-Rasmussen, M., Hummer, G. J., Kellner, A., Muirhead, E. E. and Perkins, H. H., 1971. J. Am. Med. Ass., 217, 1085.Google Scholar
Shulman, N. R. and Barker, L. F., 1969. Science, N.Y., 165, 304.CrossRefGoogle Scholar
Simon, J. B., 1971. Can. Med. Ass. J., 105, 61.Google Scholar
Stallworthy, J. A., Moolgasker, A. S. and Walsh, J. J., 1971. Lancet, 2, 1245.CrossRefGoogle Scholar
Stokes, J. and Neefe, S. R., 1945. J. Am. Med. Ass., 127, 144.CrossRefGoogle Scholar
Sturgeon, P. L., Kwak, K. S. and Gitnik, G., 1971. Vox Sang., 20, 533.CrossRefGoogle Scholar
Vierucci, A., Blumberg, B. S. and Morganti, G., 1970. Vox Sang., 19, 425.Google Scholar
Vyas, G. N. and Shulman, N. R., 1970. Science, N.Y., 170, 332.CrossRefGoogle Scholar
Walsh, J. H., Yalow, R. and Berson, S. A., 1970. J. Infect. Dis., 121, 550.CrossRefGoogle Scholar
Williams, R. G., 1969. Surgery Gynec. Obstet., 128, 1047.Google Scholar
Zucker, M. B., Pert, J. H., Lundberg, A., Yankee, R. A. and Henderson, E. S., 1969. Vox Sang., 16, 373.Google Scholar