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Malignant catarrhal fever of deer

Published online by Cambridge University Press:  05 December 2011

H. W. Reid  and
D. Buxton
H. W. Reid
Affiliation:
Animal Diseases Research Association, Moredun Institute, 408 Gilmerton Road, Edinburgh EH 17 7JH, Scotland
D. Buxton
Affiliation:
Animal Diseases Research Association, Moredun Institute, 408 Gilmerton Road, Edinburgh EH 17 7JH, Scotland
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Synopsis

Malignant catarrhal fever (MCF) is reviewed and recent findings described. It is defined as a fatal disease which affects many species of Bovidae and Cervidae, characterized by widespread necrosis and lymphoid cell proliferation and can be caused by at least two infectious agents. In Africa, a herpesvirus which infects its natural host, the wildebeest, without obvious symptoms causes substantial losses in cattle due to MCF. Elsewhere, the cause of MCF is unknown but circumstantial evidence implicates sheep as the source of infection. While cattle are infected only sporadically with this “sheep-associated” form ol disease, infection of farmed deer is common, representing the most serious disease threat to the industry.

It is considered that infection of sheep and wildebeest with their respective agents operates to their advantage, causing no disease in their natural host, while transmission to other ungulates has fatal consequences, eliminating these potentially competitive species.

Recent studies of the disease in deer and the transmission of MCF from deer to rabbits are described. The evidence suggests that the disease process involves a novel dysfunction of the immune system which results in a massive lymphoid proliferation and an atopic allergic response. It is considered that similar processes may also be involved as a component of other diseases of man and animals.

Type
Research Article
Information
Proceedings of the Royal Society of Edinburgh, Section B: Biological Sciences , Volume 82 , Issue 4: Deer, their biology, behaviour and impact , 1984 , pp. 261 - 273
Copyright
Copyright © Royal Society of Edinburgh 1984

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References

1. Alibasoglu, M., Ertark, E. and Urmann, H. K. 1973. Bovine malignant catarrh in Turkish cattle, and a report of the disease in bison. Vet. Fak. Derg. 20, 204–219.Google Scholar
2. Anderson, P. 1953. Bovine malignant catarrh in an elk. Nor. Vet. Med. 5, 847–854.Google Scholar
3. Boever, W. J. and Kurka, B. 1974. Malignant catarrhal fever in greater kudu. J. Am. Vet. Med. Assoc. 165, 817–819.Google Scholar
4. Buxton, D., Reid, H. W., Finlayson, J. and Pow, I. 1984. The pathogenesis of 'sheep-associated' malignant catarrhal fever in rabbits. Res. Vet. Sci. 36, 205–211.CrossRefGoogle ScholarPubMed
5. Buxton, D. and Reid, H. W. 1980. Transmission of malignant catarrhal fever to rabbits. Vet. Rec. 106, 243–245.CrossRefGoogle ScholarPubMed
6. Calne, R. Y., Rollis, K., White, D. J. G., Thuru, S., Evans, D. B., McMaster, P., Dunn, D. C., Craddock, G. N., Henderson, R. G., Aziz, S. and Lewis, P. 1979. Cyclosporin A initially as the only immunosuppressant in 3 recipients of cadaveric organs: 32 kidneys, 2 pancreases and 2 livers. Lancet 1979, ii, 1033–1036.CrossRefGoogle ScholarPubMed
7. Castro, A. E., Daley, G. G., Zimmer, M. A., Whitenack, D. L. and Jensen, J. 1982. Malignant catarrhal fever in an Indian gaur and greater kudu; experimental transmission, isolation and identification of a herpesvirus. Am J. Vet. Res. 43, 5–11.Google Scholar
8. Clark, K. A., Robinson, R. M., Marburger, R. G., Jones, L. P. and Orchard, J. H. 1970. Malignant catarrhal fever in Texas cervids. J. Wildl. Dis. 6, 276–383.CrossRefGoogle ScholarPubMed
9. Clarke, J. K., McFerran, J. B. and Nelson, R. T. 1973. The isolation of a strain of bovine syncytial virus in Northern Ireland. Res. Vet. Sci. 14, 117–119.CrossRefGoogle Scholar
10. Coulter, G. R. and Storz, J. 1979. Identification of a cell-associated morbillivirus from cattle affected with malignant catarrhal fever; antigenic differentiation and cytological characterization. Am J. Vet. Res. 40 1671–1677.Google Scholar
11. Daubney, R. and Hudson, J. R. 1936. Transmission experiments with bovine malignant catarrh. J. Comp. Path. Ther. 49, 63–89.CrossRefGoogle Scholar
12. Daubney, R. 1943. Malignant catarrhal fever in African buffalo. A. Rep. Kenya Vet. Dep. (1942).Google Scholar
13. Denholm, L. J. and Westbury, H. A. 1982. Malignant catarrhal fever in farmed rusa deer (Cervus. timorensis). I Clinico-pathological observations. Aust. Vet. J. 58, 81–87.CrossRefGoogle ScholarPubMed
14. Edington, N., Patel, J., Russell, P. H. and Plowright, W. 1979. The nature of the acute lymphoid proliferation in rabbits infected with the herpesvirus of bovine malignant catarrhal fever. Eur. J. Cancer 15, 1515–1522.CrossRefGoogle ScholarPubMed
15. Gotze, R. 1930. Untersuchungen über des bosartige Katarrhalfieber des Rindes. Dt. Tierärztl. Wschr. 38, 487–491.Google Scholar
16. Hamdy, F. M., Dardiri, A. H., Mebus, C., Pierson, R. E. and Johnston, D. 1978. Etiology of malignant catarrhal fever outbreak in Minnesota. Proceeding of the 82nd meeting of the United States Animal Health Association, Buffalo, New York, pp. 248–267.Google Scholar
17. Hatkin, J. 1980. Endemic malignant catarrhal fever at the San Diego wild animal park. J. Wildl. Dis. 16, 439–443.CrossRefGoogle ScholarPubMed
18. Huck, R. A., Shand, A., Allsop, P. J. and Paterson, A. B. 1961. Malignant catarrh of deer. Vet. Rec. 73, 457–465.Google Scholar
19. Huck, R. D. and Billups, L. H. 1979. Wildebeest-associated malignant cattarrhal fever in Africa: A neoplastic disease of cattle caused by an oncogenic herpesvirus? Comp. Immunol. Microbiol. Infect. Dis. 2, 275–283.Google Scholar
20. Liggitt, H. D., McChesney, A. E. and De Martini, J. S. 1980. Experimental transmission of bovine malignant catarrhal fever to a bison (Bison bison). J. Wild. Dis. 16, 299–304.CrossRefGoogle ScholarPubMed
21. Liggitt, H. D. and De Martini, J. G. 1980. The pathomorphology of malignant catarrhal fever. II Multisystematic epithelial lesions. Vet. Path. 17, 73–83.CrossRefGoogle Scholar
22. Lupke, H. F. 1906. Ueber Periarteritis nodosa bei Axishirschen. Verh. Dt. Path. Ges. 10. 140–157.Google Scholar
23. McAllum, H. J. F., Mavore, N. M. and Hemmingoen, P. 1982. A malignant catarrhal fever-like disease in red deer (Cervus elaphus) in New Zealand. N. Z. Vet. J. 30, 99–101.CrossRefGoogle Scholar
24. Mettam, R. W. M. 1923. Snotsiekte in cattle. 9th and 10th Reports of the Director of Veterinary Education and Research, Union of South Africa, pp. 395–432.Google Scholar
25. Mushi, E. Z., Rurangirwa, F. R. and Karstad, L. 1981. The shedding of malignant catarrhal fever virus by wildebeest calves. Vet. Microbiol. 6, 281–286.CrossRefGoogle Scholar
26. Parikar, N. S., Rajya, B. S. and Gill, B. S. 1975. Occurrence of malignant catarrhal fever in India. Indian Vet. J. 857–859.Google Scholar
27. Patel, J. R. and Edington, N. 1981. The detection and behaviour of the herpesvirus of malignant catarrhal fever in bovine lymphocytes. Archs Virol. 68, 321.CrossRefGoogle ScholarPubMed
28. Piercy, S. E. 1955. Studies in bovine malignant catarrh. VI Adaptation to rabbits. Br. Vet. J. 111, 484–491.CrossRefGoogle Scholar
29. Pierson, R. E.. Arango, M. and McChesney, A. E. 1973. Bovine malignant catarrhal fever in Colorado. Bovine Pract. 53, 56–59.Google Scholar
30. Pierson, R. E., Storz, J., McChesney, A. E. and Thake, D. 1974. Experimental transmission of malignant catarrhal fever. Am. J. Vet. Res. 35, 523–525.Google Scholar
31. Plowright, W., Ferris, R. D. and Scott, G. R. 1960. Blue wildebeest and the aetiological agent of malignant catarrhal fever. Nature, Land. 188, 1167–1169.CrossRefGoogle ScholarPubMed
32. Plowright, W. 1965. Malignant catarrhal fever in East Africa. 1. Behaviour of the virus in free-living populations of blue wildebeest (Gorgan laurinus taurinus, Burchell). Res. Vet. Sci. 6, 56–68.CrossRefGoogle Scholar
33. Plowright, W. 1967. Malignant catarrhal fever in East Africa. III. Neutralising antibody in free living wildebeest. Res. Vet. Sci. 8, 129–136.CrossRefGoogle Scholar
34. Plowright, W. 1968. Malignant catarrhal fever. J. Am. Vet. Med. Assoc. 152, 795–804.Google Scholar
35. Pullan, N. B. and Rowland, A. C. 1979. Bovine malignant catarrhal fever in Nigeria. Trop. Anim. Hlth Prod. 11, 117–119.CrossRefGoogle ScholarPubMed
36. Reid, H. W., Plowright, W. and Rowe, L. 1975. Neutralising antibody to herpesviruses derived from wildebeest and hartebeest in wild animals in East Africa. Res. Vet. Sci. 18, 169–273.CrossRefGoogle ScholarPubMed
37. Reid, H. W., Buxton, D., Corrigall, W., Hunter, A. R., McMartin, D. A. and Rushton, B. 1979. An outbreak of malignant catarrhal fever in red deer (Cervus elaphus). Vet. Rec. 104, 120–123.CrossRefGoogle Scholar
38. Reid, H. W., Buxton., D., Pow, I., Finlayson, J. and Berrie, E. L. 1983. A cytotoxic T-lymphocyte line propagated from a rabbit infected with sheep associated malignant catarrhal fever. Res. Vet. Sci. 34, 109–113.CrossRefGoogle ScholarPubMed
39. Roken, B. O. and Bjorklund, N. E. 1974. Malignant catarrhal fever in an animal reserve. Proceedings of the 12th Nordic Veterinary Congress, Reykjavik, pp. 197–200.Google Scholar
40. Ruth, G. R., Reed, D. E., Daley, C. A., Vorkies, M. W., Wohlgemuth, K. and Shave, H. J. 1977. Malignant catarrhal fever in bison. J. Am. Vet. Med. Assoc. 171, 913–917.Google ScholarPubMed
41. Rweymamu, M. M., Karstad, L., Mushi, E. Z., Otema, J. C. Jessett, D. M., Rowe, L., Drevemo, S. and Grootenhuis, J. G. 1974. Malignant catarrhal fever virus in nasal secretions of wildebeest: a probable mechanism tor virus transmission. J. Wildl. Dis. 10, 478–487.CrossRefGoogle Scholar
42. Rweymamu, M. M., Mushi, E. Z., Rowe, L. W. and Karstad, L. 1976. Persistent infection of cattle with the herpesvirus of malignant catarrhal fever and observations on the pathogenesis of the disease. Br. Vet. J. 132, 392–300.Google Scholar
43. Sanford, S. E., Little, P. B. and Rapley, W. A. 1977. The gross and histopathological lesions of malignant catarrhal fever in three captive Sika deer (Cervus nippon) in southern Ontario. J. Wildl. Dis. 13, 29–32.CrossRefGoogle ScholarPubMed
44. Selman, I. E., Wiseman, A., Murray, M. and Wright, N. G. 1974. A clinicopathological study of bovine malignant catarrhal fever in Great Britain. Vet. Rec. 94, 483–490.CrossRefGoogle ScholarPubMed
45. Selman, I. E., Wiseman., A., Wright, N. G. and Murray, M. 1978. Transmission studies with bovine malignant catarrhal fever. Vet. Rec. 102, 252–257.CrossRefGoogle ScholarPubMed
46. Storz, J., Okuna, M., McChesney, A. E. and Pierson, R. E. 1976. Virologic studies on cattle with naturally occurring and experimentally induced malignant catarrhal fever. Am. J. Vet. Res. 37, 875–878.Google ScholarPubMed
47. Straven, P. J. and Beckhum, J. G. 1979. Isolation of malignant catarrhal fever virus from a European bison (Bos bonus) in a zoological garden. Res. Vet. Sci. 26, 165–171.CrossRefGoogle Scholar
48. Tong, E. H., Senior, M. and Halman, C. R. E. 1961. An outbreak of malignant catarrh among the Pere David's deer. Proc. Zool. Soc. Land. 136, 477–183.CrossRefGoogle Scholar
49. Westbury, H. A. and Denholm, L. J. 1982. Malignant catarrhal fever in farmed rusa deer (Cervus timorensis). 2. Animal transmission and virological studies. Aust. Vet. J. 58, 88–92.CrossRefGoogle ScholarPubMed
50. Whitenach, D. L., Castro, A. E. and Kocan, A. A. 1981. Experimental malignant catarrhal fever (African form) in white-tailed deer. J. Wildl. Dis. 17, 322–451.Google Scholar
51. Wyand, D. S., Helmboldt, C. F. and Nielson, S. W. 1971. Malignant catarrhal fever in white tailed deer. J. Am. Vet. Med. Ass. 159, 605–610.Google Scholar
52. Zimmer, M. A., McCoy., C. P. and Jensen, J. M. 1981. Comparative pathology of the African form in captive Indian gaur and domestic cattle. J. Am. Vet. Med. Ass. 180, 1130–1135.Google Scholar
53. Zinser, H. 1935. In Rats, Lice and History. London: George Routledge and Sons.Google Scholar