The existence and uniqueness of travelling-wave solutions is investigated for a system of two reaction–diffusion equations where one diffusion constant vanishes. The system arises in population dynamics and epidemiology. Travelling-wave solutions satisfy a three-dimensional system about (u, u′, ν), whose equilibria lie on the u-axis. Our main result shows that, given any wave speed c > 0, the unstable manifold at any point (a, 0, 0) on the u-axis, where a ∈ (0, γ) and γ is a positive number, provides a travelling-wave solution connecting another point (b, 0, 0) on the u-axis, where b:= b(a) ∈ (γ, ∞), and furthermore, b(·): (0, γ) → (γ, ∞) is continuous and bijective