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Nutrition, exercise and the immune system

Published online by Cambridge University Press:  28 February 2007

Bente Klarlund Pedersen*
Affiliation:
The Copenhagen Muscle Research Centre, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Kenneth Ostrowski
Affiliation:
The Copenhagen Muscle Research Centre, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Thomas Rohde
Affiliation:
The Copenhagen Muscle Research Centre, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Helle Bruunsgaard
Affiliation:
The Copenhagen Muscle Research Centre, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
*
*Corresponding author: Dr B. K. Pedersen, fax 00 45 35 45 6648, email [email protected]
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Abstract

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Type
Meeting Report
Copyright
Copyright © The Nutrition Society 1998

References

Anderson, R & Lukey, PT (1987) A biological role for ascorbate in the selective neutralization of extracellular phagocyte-derived oxidants. Annals of the New York Academy of Sciences 498, 229247.CrossRefGoogle ScholarPubMed
Ardawi, MS & Newsholme, EA (1984) Intracellular localization and properties of phosphate-dependent glutaminase in rat mesenteric lymph nodes. Biochemical Journal 217, 289296.CrossRefGoogle ScholarPubMed
Babior, BM (1984) Oxidants from phagocytes: agents of defense and destruction. Blood 64, 959966.CrossRefGoogle ScholarPubMed
Bagby, GJ, Crouch, LD & Shepherd, RE (1996) Exercise and cytokines: Spontaneous and elicited response. In Exercise and Immune Function, pp. 5578 [Hoffman-Goetz, L, editor]. New York: CRC Press.Google Scholar
Benquet, C, Krzystyniak, K, Savard, & Guertin, F (1994) Modulation of exercise-induced immunosuppression by dietary polyunsaturated fatty acids in mice. Journal of Toxicology and Environmental Health 43, 225237.CrossRefGoogle ScholarPubMed
Bruunsgaard, H, Galbo, H, Halkjaer-Kristensen, J, Johansen, TL, MacLean, D & Pedersen, BK (1997) Exercise-induced increase in interleukin-6 is related to muscle damage. Journal of Physiology 499, 833841.CrossRefGoogle ScholarPubMed
Cannon, JG, Evans, WJ, Hughes, VA, Meredith, C & Dinarello, CA (1986) Physiological mechanisms contributing to increased interleukin-1 secretion. Journal of Applied Physiology 61, 18691874.CrossRefGoogle ScholarPubMed
Cannon, J & Kluger, MJ (1983) Endogenous pyrogen activity in human plasma after exercise. Science 220, 617619.CrossRefGoogle ScholarPubMed
Cannon, JG, Meydani, SN, Fielding, RA, Fiatarone, MA, Meydani, M, Farhangmehr, M, Orencole, SF, Blumberg, JB & Evans, WJ (1991) Acute phase response in exercise. II. Associations between vitamin E, cytokines, and muscle proteolysis. American Journal of Physiology 260, R1235R1240.Google ScholarPubMed
Cannon, JG, Orencole, SF, Fielding, RA, Meydani, M, Meydani, SN, Fiatarone, MA, Blumberg, JB & Evans, WJ (1990) Acute phase response in exercise: interaction of age and vitamin E on neutrophils and muscle enzyme release. American Journal of Physiology 259, R1214R1219.Google ScholarPubMed
Davies, KJA, Packer, L & Brooks, GA (1982) Freeradicals and tissue produced by exercise. Biochemical and Biophysical Research Communications 107, 11981205.CrossRefGoogle Scholar
Essen, P, Wemerman, J, Sonnenfeld, T, Thunell, S &Vinnars, E (1992) Free amino acids in plasma and muscle during 24 hourspost-operatively-a descriptive study. Clinical Physiology 12, 163177.CrossRefGoogle ScholarPubMed
Evans, WJ, Meredith, CN, Cannon, JG, Dinarello, CA, Frontera, WR, Hughes, VA, Jones, BH & Knuttgen, HG (1986) Metabolic changes following eccentric exercise in trained and untrained men. Journal of Applied Physiology 61, 18641868.CrossRefGoogle ScholarPubMed
Fitzgerald, L (1988) Exercise and the immune system. Immunology Today 9, 337339.CrossRefGoogle ScholarPubMed
Fitzgerald, L (1991) Overtraining increases the susceptibility to infection. Internationl Journal of Sports Medicine 12, S5S8.CrossRefGoogle ScholarPubMed
Hemila, H (1992) Vitamin C and the common cold. British Journal of Nutrition 67, 316.CrossRefGoogle ScholarPubMed
Hoffman-Goetz, L & Pedersen, BK (1994) Exercise and theimmune system: a model of the stress response? Immunology Today 15, 382387.CrossRefGoogle Scholar
Johnson JA, III, Griswold, J & Muakkassa, FF (1993)Essential fatty acids influence survival in sepsis. Journal of Trauma 35, 128131.CrossRefGoogle ScholarPubMed
Kasama, TK, Kobayashi, T, Fukushima, M, Tabata, M, Ohno, I, Negishi, M, Ide, H, Takahashi, T & Niwa, Y (1989) Production of interleukin 1-like factor from human peripheral blood monocytes and polymorphonuclear leukocytes by superoxide anion: the role of interleukin 1 and reactive oxygen species in inflamed sites. Immunology and Immunopathology 53, 439448.CrossRefGoogle ScholarPubMed
Keast, D, Arstein, D, Harper, W, Fry, R & Morton, AR (1995) Depression of plasma glutamine concentration after exercise stress and its possible influence on the immune system. Medical Journal of Australia 162, 1518.CrossRefGoogle ScholarPubMed
Lehmann, M, Huonker, M, Dimeo, F, Heinz, N, Gastmann, U, Treis, N, Steinacker, JM, Keul, J, Kajewski, R & Haussinger, D (1995) Serum amino acid concentrations in nine athletes before and after the 1993 Colmar ultra triathlon. International Journal of Sports Medicine 16, 155159.CrossRefGoogle ScholarPubMed
McCarthy, D & Dale, MM (1988) The leucocytosis of exercise. A review and model. Sports Medicine 6, 333363.CrossRefGoogle ScholarPubMed
Nash, HL (1987) Can exercise make us immune to disease? Physician and Sports Medicine 250253.Google Scholar
Newsholme, EA (1990) Psychoimmunology and cellular nutrition: an alternative hypothesis (editorial). Biological Psychiatry 27, 13.CrossRefGoogle Scholar
Newsholme, EA (1994) Biochemical mechanism s to explain immunosuppression in well-trained and overtrained athletes. International Journal of Sports Medicine 15, Suppl. 3, S142S147.CrossRefGoogle Scholar
Nieman, DC (1994 a) Exercise, infection, and immunity. International Journal of Sports Medicine 15, Suppl. 3, S131S141.CrossRefGoogle ScholarPubMed
Nieman, DC (1994 b) Exercise, upper respiratory tract infection, and the immune system. Medicine and Science in Sports and Exercise 26, 128139.CrossRefGoogle ScholarPubMed
Nieman, DC (1996) Prolonged aerobic exercise, immune response, and riskof infection. In Exercise and Immune Function, pp. 143162 [Hoffman-Goetz, L, editor]. New York: CRC Press.Google Scholar
Nieman, DC & Henson, DA (1994) Role of endurance exercise in immune senescence. Medicine and Science in Sports and Exercise 26, 172181.CrossRefGoogle ScholarPubMed
Nieman, DC, Henson, DA, Gusewitch, G, Warren, BJ, Dotson, RC, Butterworth, DE & Nehlsen Cannarella, SL (1993)Physical activity and immune function in elderly women. Medicine and Science in Sports and Exercise 25, 823831.CrossRefGoogle ScholarPubMed
Nieman, DC, Johanssen, LM & Lee, JW (1989) Infectious episodes in runners before and after a roadrace. Journal of Sports Medicine and Physical Fitness 29, 289296.Google ScholarPubMed
Nieman, DC, Johanssen, LM, Lee, JW & Arabatzis, K (1990 a) Infectious episodes in runners before and after the Los Angeles Marathon. Journal of Sports Medicine and Physical Fitness 30, 316328.Google ScholarPubMed
Nieman, DC, Nehlsen cannarella, SL, Markoff, PA, Balk lamberton, AJ, Yang, H, Chritton, DB, Lee, JW & Arabatzis, K (1990 b) The effects of moderate exercise training on natural killer cells and acute upper respiratory tract infections. International Journal of Sports Medicine 11, 467473.CrossRefGoogle ScholarPubMed
Northoff, H & Berg, A (1991) Immunologic mediators as parameters of the reaction to strenuous exercise. International Journal of Sports Medicine 12, S9S15.CrossRefGoogle ScholarPubMed
Parry billings, M, Budgett, R, Koutedakis, Y, Blomstrand, E, Brooks, S, Williams, C, Calder, PC, Pilling, S, Baigrie, R & Newsholme, EA (1992) Plasma amino acid concentrations in the overtraining syndrome: possible effects on the immune system. Medicine and Science in Sports and Exercise 24, 13531358.CrossRefGoogle ScholarPubMed
Pedersen, BK (1997) Exercise Immunology, pp. 1206. Austin, TX: R. G. Landes Bioscience.Google Scholar
Pedersen, BK, Bruunsgaard, H, Klokker, M, Kappel, M, Maclean, DA, Nielsen, HB, Rohde, T, Ullum, H & Zacho, M (1996) Exercise-induced immunomodulation-possible roles of neuroendocrine factors and metabolic factors. International Journal of Sports Medicine 18, S2S7.CrossRefGoogle Scholar
Pedersen, BK, Tvede, N, Klarlund, K, Christensen, LD, Hansen, FR, Galbo, H, Kharazmi, A & Halkjaer kristensen, J (1990) Indomethacin in vitro and in vivo abolishes post-exercise suppression of natural killer cell activity in peripheral blood. International Journal of Sports Medicine 11, 127131.CrossRefGoogle ScholarPubMed
Peters, EM & Bateman, ED (1983) Ultramarathon running and upper respiratory tract infections: An epidemiological survey. South African Medical Journal 64, 582584.Google ScholarPubMed
Peters, EM, Cambell, A & Pawley, L (1992) Vitamin A fails to increase resistance to upper respiratory tract infection in distance runners. South African Journal of Sports Medicine 7, 37.Google Scholar
Peters, EM, Goetzsche, JM, Grobbelaar, B & Noakes, TD (1993) Vitamin C supplementation reduces the incidence of postrace symptomsof upper-respiratory-tract infection in ultramarathon runners. American Journal of Clinical Nutrition 57, 170174.CrossRefGoogle Scholar
Sprenger, H, Jacobs, C, Nain, M, Gressner, AM, Prinz, H, Wesemann, W & Gemsa, D (1992) Enhanced release of cytokines, interleukin-2 receptors, and neopterin after long-distance running. Clinical Immunology and Immunopathology 63, 188195.CrossRefGoogle ScholarPubMed
Tvede, N, Heilmann, C, Halkjaer kristensen, J & Pedersen, BK (1989) Mechanisms of B-lymphocyte suppression induced by acute physical exercise. Journal of Clinical Laboratory Immunology 30, 169173.Google ScholarPubMed
Ullum, H, Haahr, PM, Diamant, M, Palmo, J, Halkjaer kristensen, J & Pedersen, BK (1994) Bicycle exercise enhancesplasma IL-6 but does not change IL lα, IL 1β, IL-6, or TNF-α pre-mRNA in BMNC. Journal of Applied Physiology 77, 9397.CrossRefGoogle ScholarPubMed