Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-11-25T00:49:37.680Z Has data issue: false hasContentIssue false

Lipoprotein lipase: regulation and role in lipoprotein metabolism

Published online by Cambridge University Press:  28 February 2007

T. Olivecrona
Affiliation:
Department of Medical Biochemistry and Biophysics, Umeå University, S-90187 Umeå, Sweden
M. Hultin
Affiliation:
Department of Medical Biochemistry and Biophysics, Umeå University, S-90187 Umeå, Sweden
M. Bergö
Affiliation:
Department of Medical Biochemistry and Biophysics, Umeå University, S-90187 Umeå, Sweden
G. Olivecrona
Affiliation:
Department of Medical Biochemistry and Biophysics, Umeå University, S-90187 Umeå, Sweden
Rights & Permissions [Opens in a new window]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Research Article
Copyright
Copyright © The Nutrition Society 1997

References

REFERENCES

Bergö, M., Olivecrona, G. & Olivecrona, T. (1996 a). Diurnal rhythms and effects of fasting and re-feeding on rat adipose tissue lipoprotein lipase. American Journal of Physiology 271, E1092E1097.Google Scholar
Bergö, M., Olivecrona, G. & Olivecrona, T. (1996 b). Forms of lipoprotein lipase in rat tissues: In adipose tissue the proportion of inactive lipase increases on fasting. Biochemical Journal 313, 893898.Google Scholar
Bragdon, J. H. & Gordon, R. S. (1958). Tissue distribution of C14 after the intravenous injection of labeled chylomicrons and unesterified fatty acids in the rat. Journal of Clinical Investigation 37, 574578.Google Scholar
Brunzell, J. D. (1995). Familial lipoprotein lipase deficiency and other causes of the chylomicronemia syndrome. In Metabolic Basis of Inherited Disease, pp. 19131932 [Scriver, C. R., Beaudet, A. L., Sly, W. S. and Valle, D., editors]. New York: McGraw-Hill Book Co.Google Scholar
Cryer, A., Riley, S. E., Williams, E. R. & Robinson, D. S. (1976). Effect of nutritional status on rat adipose tissue, muscle and post-heparin plasma clearing factor lipase activities: their relationship to triglyceride fatty acid uptake by fat-cells and to plasma insulin concentrations. Clinical Science and Molecular Medicine 50, 213221.Google Scholar
Doolittle, M. H., Ben-Zeev, O., Elovson, J., Martin, D. & Kirchgessner, T. G. (1990). The response of lipoprotein lipase to feeding and fasting. Evidence for posttranslational regulation. Journal of Biological Chemistry 265, 45704577.Google Scholar
Frayn, K. N., Coppack, S. W., Fielding, B. A. & Humphreys, S. M. (1995). Coordinated regulation of hormonesensitive lipase and lipoprotein lipase in human adipose tissue in vivo: Implications for the control of fat storage and fat mobilization. Advances in Enzyme Regulation 35, 163178.Google Scholar
Harris, K. L. & Harris, P. A. (1973). Kinetics of chylomicron triglyceride removal from plasma in rats: Effect of dose on the volume of distribution. Biochimica et Biophysica Acta 326, 1216.CrossRefGoogle ScholarPubMed
Hultin, M., Savonen, R. & Olivecrona, T. (1996). Chylomicron metabolism in rats: Lipolysis, recirculation of triglyceride-derived fatty acids in plasma FFA, and fate of core lipids as analyzed by compartmental modelling. Journal of Lipid Research 37, 10221036.CrossRefGoogle ScholarPubMed
Karpe, F. & Hultin, M. (1995). Endogenous triglyceride-rich lipoproteins accumulate in rat plasma when competing with a chylomicron-like triglyceride emulsion for a common lipolytic pathway. Journal of Lipid Research 36, 15571566.Google Scholar
Levak-Frank, S., Radner, H., Walsh, A., Stollberger, R., Knipping, G., Hoefler, G., Sattler, W., Weinstock, P. H., Breslow, J. L. & Zechner, R. (1995). Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice. Journal of Clinical Investigation 96, 976986.Google Scholar
Olivecrona, G. & Olivecrona, T. (1995). Triglyceride lipases and atherosclerosis. Current Opinion in Lipidology 6, 291305.Google Scholar
Raynolds, M. V., Awald, P. D., Gordon, D. F., Gutierrez-Hartmann, A., Rule, D. C., Wood, W. M. & Eckel, R. H. (1990). Lipoprotein lipase gene expression in rat adipocytes is regulated by isoproterenol and insulin through different mechanisms. Molecular Endocrinology 4, 14161422.Google Scholar
Samra, J. S., Clark, M. L., Humphreys, S. M., Macdonald, I. A. & Frayn, K. N. (1996). Regulation of lipid metabolism in adipose tissue during early starvation. American Journal of Physiology 271, E541E546.Google ScholarPubMed