Hostname: page-component-cd9895bd7-dk4vv Total loading time: 0 Render date: 2024-12-22T15:26:29.977Z Has data issue: false hasContentIssue false
  • English
  • Français

Fuel selection in white adipose tissue

Published online by Cambridge University Press:  28 February 2007

Keith N. Frayn ,
Sandy M. Humphreys  and
Simon W. Coppack
Keith N. Frayn
Affiliation:
Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE
Sandy M. Humphreys
Affiliation:
Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE
Simon W. Coppack
Affiliation:
Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Meeting Report
Information
Proceedings of the Nutrition Society , Volume 54 , Issue 1 , March 1995 , pp. 177 - 189
Copyright
Copyright © The Nutrition Society 1995

References

Abumrad, N. A., Park, J. H. & Park, C. R. (1984). Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. Journal of Biological Chemistry 259, 8945–8953.CrossRefGoogle ScholarPubMed
Arner, P., Kriegholm, E., Engfeldt, P. & Bolinder, J. (1990). Adrenergic regulation of lipolysis in situ at rest and during exercise. Journal of Clinical Investigation 85, 893–898.CrossRefGoogle ScholarPubMed
Baldo, A., Sniderman, A. D., St-Luce, S., Avramoglu, R. K., Maslowska, M., Hoang, B., Monge, J. C., Bell, A., Mulay, S. & Cainflone, K. (1993). The adipsin-acylation stimulating protein system and regulation of intracellular triglyceride synthesis. Journal of Clinical Investigation 92, 1543–1547.CrossRefGoogle ScholarPubMed
Belfrage, P., Fredrikson, G., Olsson, H. & Strålfors, P. (1985). Molecular mechanisms for hormonal control of adipose tissue lipolysis. International Journal of Obesity 9, Suppl. 1, 129–136.Google ScholarPubMed
Bonadonna, R. C., Groop, L. C., Zych, K., Shank, M. & DeFronzo, R. A. (1990). Dose-dependent effect of insulin on plasma free fatty acid turnover and oxidation in humans. American Journal of Physiology 259, E736–E750.Google ScholarPubMed
Boulton, K. L., Hudson, D. U., Coppack, S. W. & Frayn, K. N. (1992). Steroid hormone interconversions in human adipose tissue in vivo. Metabolism 41, 556–559.CrossRefGoogle ScholarPubMed
Carlson, M. G., Snead, W. L. & Campbell, P. J. (1993). Regulation of free fatty acid metabolism by glucagon. Journal of Clinical Endocrinology and Metabolism 77, 11–15.Google ScholarPubMed
Carlson, M. G., Snead, W. L., Hill, J. O., Nurjhan, N. & Campbell, P. J. (1991). Glucose regulation of lipid metabolism in humans. American Journal of Physiology 261, E815–E820.Google ScholarPubMed
Coppack, S. W., Evans, R. D., Fisher, R. M., Frayn, K. N., Gibbons, G. F., Humphreys, S. M., Kirk, M. J., Potts, J. L. & Hockaday, T. D. R. (1992). Adipose tissue metabolism in obesity: lipase action in vivo before and after a mixed meal. Metabolism 41, 264–272.CrossRefGoogle ScholarPubMed
Coppack, S. W., Fisher, R. M., Gibbons, G. F., Humphreys, S. M., McDonough, M. J., Potts, J. L. & Frayn, K. N. (1990 a). Postprandial substrate deposition in human forearm and adipose tissues in vivo. Clinical Science 79, 339–348.CrossRefGoogle ScholarPubMed
Coppack, S. W., Frayn, K. N., Humphreys, S. M., Dhar, H. & Hockaday, T. D. R. (1989 a). Effects of insulin on human adipose tissue metabolism in vivo. Clinical Science 77, 663–670.CrossRefGoogle ScholarPubMed
Coppack, S. W., Frayn, K. N., Humphreys, S. M., Whyte, P. L. & Hockaday, T. D. R. (1990 b). Arteriovenous differences across human adipose and forearm tissues after overnight fast. Metabolism 39, 384–390.CrossRefGoogle ScholarPubMed
Coppack, S. W., Frayn, K. N., Whyte, P. L. & Humphreys, S. M. (1989 b). Carbohydrate metabolism in human adipose tissue in vivo. Biochemical Society Transactions 17, 145–146.CrossRefGoogle Scholar
Coppack, S. W., Jensen, M. D. & Miles, J. M. (1994). In vivo regulation of lipolysis in humans. Journal of Lipid Research 35, 177–193.CrossRefGoogle ScholarPubMed
Coppack, S. W. & Miles, J. M. (1992). Ketone body metabolism by human adipose tissue. Diabetologia 35, Suppl. 1, A8.Google Scholar
Dawson-Hughes, B., Shipp, C., Sadowski, L. & Dallal, G. (1987). Bone density of the radius, spine, and hip in relation to percent of ideal body weight in postmenopausal women. Calcified Tissue International 40, 310–314.CrossRefGoogle ScholarPubMed
Eckel, R. H. (1989). Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases. New England Journal of Medicine 320, 1060–1068.Google ScholarPubMed
Edens, N. K., Leibel, R. L. & Hirsch, J. (1990). Mechanism of free fatty acid re-esterification in human adipocytes in vitro. Journal of Lipid Research 31, 1423–1431.CrossRefGoogle ScholarPubMed
Elia, M. (1992). Organ and tissue contribution to metabolic rate. In Energy Metabolism: Tissue Determinants and Cellular Corollaries, pp. 61–79 [Kinney, J. M. and Tucker, H. N., editors]. New York: Raven Press.Google Scholar
Frayn, K. N. (1992). Studies of human adipose tissue in vivo. In Energy Metabolism: Tissue Determinants and Cellular Corollaries, pp. 267–295 [Kinney, J. M. and Tucker, H. N. editors]. New York: Raven Press.Google Scholar
Frayn, K. N., Coppack, S. W. & Humphreys, S. M. (1993 a). Subcutaneous adipose tissue metabolism studied by local catheterization. International Journal of Obesity 17, Suppl. 3, S18–S21.Google ScholarPubMed
Frayn, K. N., Coppack, S. W., Humphreys, S. M., Clark, M. L. & Evans, R. D. (1993 b). Periprandial regulation of lipid metabolism in insulin-treated diabetes mellitus. Metabolism 42, 504–510.CrossRefGoogle ScholarPubMed
Frayn, K. N., Coppack, S. W., Humphreys, S. M. & Whyte, P. L. (1989). Metabolic characteristics of human adipose tissue in vivo. Clinical Science 76, 509–516.CrossRefGoogle ScholarPubMed
Frayn, K. N., Coppack, S. W. & Potts, J. L. (1992). Effect of diet on human adipose tissue metabolism. Proceedings of the Nutrition Society 51, 409–418.CrossRefGoogle ScholarPubMed
Frayn, K. N., Coppack, S. W., Walsh, P. E., Butterworth, H. C., Humphreys, S. M. & Pedrosa, H. C. (1990). Metabolic responses of forearm and adipose tissues to acute ethanol ingestion. Metabolism 39, 958–966.CrossRefGoogle ScholarPubMed
Frayn, K. N., Khan, K., Coppack, S. W. & Elia, M. (1991). Amino acid metabolism in human subcutaneous adipose tissue in vivo. Clinical Science 80, 471–474.CrossRefGoogle ScholarPubMed
Frayn, K. N., Shadid, S., Hamlani, R., Humphreys, S. M., Clark, M. L., Fielding, B. A., Boland, O. & Coppack, S. W. (1994). Regulation of fatty acid movement in human adipose tissue in the postabsorptive-to-postprandial transition. American Journal of Physiology 266, E308–E317.Google ScholarPubMed
Hammond, V. A. & Johnston, D. G. (1987). Substrate cycling between triglyceride and fatty acid in human adipocytes. Metabolism 36, 308–313.CrossRefGoogle ScholarPubMed
Harmon, C. M., Luce, P. & Abumrad, N. A. (1992). Labelling of an 88 kDa adipocyte membrane protein by sulpho-N-succinimidyl long-chain fatty acids: inhibition of fatty acid transport. Biochemical Society Transactions 20, 811–813.CrossRefGoogle ScholarPubMed
Harper, R. D. & Saggerson, E. D. (1976). Factors affecting fatty acid oxidation in fat cells isolated from rat white adipose tissue. Journal of Lipid Research 17, 516–526.CrossRefGoogle ScholarPubMed
Jensen, M. D., Caruso, M., Heiling, V. & Miles, J. M. (1989). Insulin regulation of lipolysis in nondiabetic and IDDM subjects. Diabetes 38, 1595–1601.CrossRefGoogle ScholarPubMed
Jensen, M. D., Heiling, V. J. & Miles, J. M. (1991). Effects of glucagon on free fatty acid metabolism in humans. Journal of Clinical Endocrinology and Metabolism 72, 308–315.CrossRefGoogle ScholarPubMed
Kowalski, T. J. & Watford, M. (1994). Production of glutamine and utilization of glutamate by rat subcutaneous adipose tissue in vivo. American Journal of Physiology 266, E151–E154.Google ScholarPubMed
Lafontan, M. & Langin, D. (1995). Cellular aspects of fuel mobilization and selection in white adipocytes. Proceedings of the Nutrition Society 54, 49–63.CrossRefGoogle ScholarPubMed
Leboeuf, B. (1965). Regulation of fatty acid esterification in adipose tissue incubated in vitro. In Handbook of Physiology Section 5: Adipose Tissue, pp. 385–391 [Renold, A. E. and Cahill, G. F., editors]. Washington, DC: American Physiological Society.Google Scholar
Mårin, P., Rebuffé-Scrive, M., Smith, U. & Björntorp, P. (1987). Glucose uptake in human adipose tissue. Metabolism 36, 1154–1160.CrossRefGoogle ScholarPubMed
Napolitano, A., Lowell, B. B., Damm, D., Leibel, R. L., Ravussin, E., Jimerson, D. C., Lesem, M. D., Van Dyke, D. C., Daly, P. A., Chatis, P., White, R. T., Spiegelman, B. M. & Flier, J. S. (1994). Concentrations of adipsin in blood and rates of adipsin secretion by adipose tissue in humans with normal, elevated and diminished adipose tissue mass. International Journal of Obesity 18, 213–218.Google ScholarPubMed
Ong, J. M. & Kern, P. A. (1989). Effect of feeding and obesity on lipoprotein lipase activity, immunoreactive protein, and messenger RNA levels in human adipose tissue. Journal of Clinical Investigation 84, 305–311.CrossRefGoogle ScholarPubMed
Pedersen, O., Kahn, C. R. & Kahn, B. B. (1992). Divergent regulation of the Glut 1 and Glut 4 glucose transporters in isolated adipocytes from Zucker rats. Journal of Clinical Investigation 89, 1964–1973.CrossRefGoogle ScholarPubMed
Potts, J. L., Fisher, R. M., Humphreys, S. M., Coppack, S. W., Gibbons, G. F. & Frayn, K. N. (1991). Peripheral triacylglycerol extraction in the fasting and post-prandial states. Clinical Science 81, 621–626.CrossRefGoogle ScholarPubMed
Richelsen, B. (1992). Release and effects of prostaglandins in adipose tissue. Prostaglandins, Leukotrienes and Essential Fatty Acids 47, 171–182.CrossRefGoogle ScholarPubMed
Rigden, D. J., Jellyman, A. E., Frayn, K. N. & Coppack, S. W. (1990). Human adipose tissue glycogen levels and responses to carbohydrate feeding. European Journal of Clinical Nutrition 44, 689–692.Google ScholarPubMed
Sadur, C. N. & Eckel, R. H. (1982). Insulin stimulation of adipose tissue lipoprotein lipase. Use of the euglycemic clamp technique. Journal of Clinical Investigation 69, 1119–1125.CrossRefGoogle ScholarPubMed
Siiteri, P. K. (1987). Adipose tissue as a source of hormones. American Journal of Clinical Nutrition 45, 277–282.CrossRefGoogle ScholarPubMed
Snell, K. & Duff, D. A. (1977). Alanine release by rat adipose tissue in vitro. Biochemical and Biophysical Research Communications 77, 925–932.CrossRefGoogle ScholarPubMed
Sniderman, A., Baldo, A. & Cainflone, K. (1992). The potential role of acylation stimulating protein as a determinant of plasma triglyceride clearance and intracellular triglyceride synthesis. Current Opinion in Lipidology 3, 202–207.CrossRefGoogle Scholar
Taylor, R., Husband, D. J., Marshall, S. M., Tunbridge, W. M. G. & Alberti, K. G. M. M. (1984). Adipocyte insulin binding and insulin sensitivity in ‘brittle’ diabetes. Diabetologia 27, 441–446.CrossRefGoogle ScholarPubMed
Tischler, M. E. & Goldberg, A. L. (1980). Leucine degradation and release of glutamine and alanine by adipose tissue. Journal of Biological Chemistry 255, 8074–8081.CrossRefGoogle ScholarPubMed
Wu, M. S., Jeng, C. Y., Hollenbeck, C. B., Chen, Y.-D. I., Jaspan, J. & Reaven, G. M. (1990). Does glucagon increase plasma free fatty acid concentration in humans with normal glucose tolerance? Journal of Clinical Endocrinology and Metabolism 70, 410–416.CrossRefGoogle ScholarPubMed