We give several sufficient conditions on a pair of Banach spaces X and Y under which each Lipschitz mapping from a domain in X to Y has, for every $\epsilon > 0$, a point of $\epsilon$-Fréchet differentiability. Most of these conditions are stated in terms of the moduli of asymptotic smoothness and convexity, notions which have appeared in the literature under a variety of names. We prove, for example, that for $\infty > r > p \ge 1$, every Lipschitz mapping from a domain in an $\ell_r$-sum of finite-dimensional spaces into an $\ell_p$-sum of finite-dimensional spaces has, for every $\epsilon > 0$, a point of $\epsilon$-Fréchet differentiability, and that every Lipschitz mapping from an asymptotically uniformly smooth space to a finite-dimensional space has such points. The latter result improves, with a simpler proof, an earlier result of the second and third authors. We also survey some of the known results on the notions of asymptotic smoothness and convexity, prove some new properties, and present some new proofs of existing results.

2000 Mathematical Subject Classification: 46G05, 46T20.