Core collapse supernovae are responsible for at least half of the galactic inventory of Fe-group elements and probably for most of the Fe-group abundances seen in metal poor stars. Recent simulations show the emergence of a proton-rich ($Y_e>0.5$) region in the innermost ejected mass zones due to the neutrino interaction with matter. We explore the nucleosynthesis implications of these findings that result in enhanced abundances of 45Sc, 49Ti, and 64Zn, which is consistent with chemical evolution studies and observations of low metallicity stars.