Super-star clusters are probably the largest star-forming entities in our local Universe, containing hundreds of thousands to millions of young stars usually within less than a few parsecs. While no such systems are known in the Milky Way (MW), they are found especially in pairs of interacting galaxies but also in some dwarf galaxies like R 136 in the Large Magelanic Cloud (LMC). With the use of SPH calculations we show that a natural explanation for this phenomenon is the presence of shear in normal spiral galaxies which facilitates the formation of low-density loose OB associations from giant molecular clouds (GMC) instead of dense super-star clusters. In contrast, in interacting galaxies and in dwarf galaxies, regions can collapse without having a large-scale sense of rotation. This lack of rotational support allows the giant molecular clouds to concentrate into a single, dense and gravitationally bound system.