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Published online by Cambridge University Press: 20 November 2017
The 16kDa peptide hormone leptin is an adipose tissue-derived regulator of food intake and energy homeostasis, and a signal of the status of body energy stores to the brain. Plasma levels of leptin reflect body fat mass in humans, rodents and ruminants (Houseknecht et al., 1998; Delavaud et al., 2000). The aim of this study was to investigate circadian rhythms of plasma leptin and other metabolic variables in rabbits, to assess the influence of the timing of food intake and to investigate the relationship between leptin and lipid metabolites.