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The effect of molybdenum, iron and sulphur supplementation on immune function in growing lambs

Published online by Cambridge University Press:  20 November 2017

C.L. Williams ,
A.M. Mackenzie  and
R.G. Wilkinson
C.L. Williams
Affiliation:
ASRC, Harper Adams University College, Edgmond, Newport, Shropshire TF10 8NB, UK
A.M. Mackenzie
Affiliation:
ASRC, Harper Adams University College, Edgmond, Newport, Shropshire TF10 8NB, UK
R.G. Wilkinson
Affiliation:
ASRC, Harper Adams University College, Edgmond, Newport, Shropshire TF10 8NB, UK
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Extract

Clinical copper (Cu) deficiency in ruminant animals is mainly attributed to antagonistic interactions with molybdenum (Mo), iron (Fe) and sulphur (S) and Williams et al. (2001) reported differential effects between Mo and S, compared with Fe and S on various copper parameters. Suttle and Jones (1986) reported an increased mortality of lambs and infection rate due to copper deficiency which suggests an effect of Cu deficiency on immune function. The aim of this study was to assess the effects of Mo or Fe and S on the cellular and humoral immune responses of growing lambs.

Type
Poster Presentations
Information
Proceedings of the British Society of Animal Science , Volume 2002 , 2002 , pp. 203
Copyright
Copyright © The British Society of Animal Science 2002

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References

Mosmann, T. 1983 Rapid colorimetric assay for cellular growth and survival: Application of proliferation and cytotoxicity assays Journal of Immunological Methods 65: 55–63 Google Scholar
Suttle, N.F. and Jones, D.G. 1986 Copper and disease resistance in sheep: a rare natural confirmation of interaction between specific nutrient and infection. Proceedings of the Nutrition Society 45: 317–325 Google Scholar
Ward, J.D., Gengelbach, G.P. and Spears, J.W. 1997 The effects of copper deficiency with or without high dietary iron or molybdenum on immune function of cattle. Journal of Animal Science 75: 1400–1408 CrossRefGoogle ScholarPubMed
Williams, C.L., Mackenzie, A.M., Illingworth, D.V. and Wilkinson, R.G. 2001 The effect of molybdenum, iron and sulphur supplementation on growth rate and copper status of lambs. Proceedings of the British Society of Animal Science 140 CrossRefGoogle Scholar