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Effect of dietary polyunsaturated fatty acids on ex-vivo lymphocyte stimulation response to Cooperia onchophara L3 antigen in calves

Published online by Cambridge University Press:  20 November 2017

K.N. Muturi ,
M. Birnie ,
M. Wallace ,
J. Struthers ,
J. R. Scaife ,
M.A. Lomax  and
R. Barker
K.N. Muturi*
Affiliation:
Department of Agriculture and Forestry, University of Aberdeen, 581 King Street, Aberdeen, AB24 5UA, UK
M. Birnie
Affiliation:
Department of Agriculture and Forestry, University of Aberdeen, 581 King Street, Aberdeen, AB24 5UA, UK
M. Wallace
Affiliation:
Department of Agriculture and Forestry, University of Aberdeen, 581 King Street, Aberdeen, AB24 5UA, UK
J. Struthers
Affiliation:
Department of Agriculture and Forestry, University of Aberdeen, 581 King Street, Aberdeen, AB24 5UA, UK
J. R. Scaife
Affiliation:
Department of Agriculture and Forestry, University of Aberdeen, 581 King Street, Aberdeen, AB24 5UA, UK
M.A. Lomax
Affiliation:
Department of Agriculture and Forestry, University of Aberdeen, 581 King Street, Aberdeen, AB24 5UA, UK
R. Barker
Affiliation:
Department of Medicine and therpeutics, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD., U.K
*
[email protected]
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Extract

Dietary polyunsaturated fatty acids (PUFA) are known to influence the fatty acid composition of immune and inflammatory cell membranes (Yaqoob et al, 1995). Changing the fatty acid composition and the n-6/n-3 PUFA ratio of cell membranes has been reported to have profound effects on immune cell functionality (Blok et al, 1996). Immune responses to Cooperia onchophara, a nematode parasite that infects calves, are usually slow to develop and inappropriate. The aim of this experiment was to establish the extent to which supplementation of pre-ruminant calves with an n-6 or n-3 PUFA source may influence ex-vivo lymphocyte response to an L3 C onchophara antigen.

Type
Poster Presentations
Information
Proceedings of the British Society of Animal Science , Volume 2003 , 2003 , pp. 88
Copyright
Copyright © The British Society of Animal Science 2003

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References

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