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Published online by Cambridge University Press: 20 November 2017
Biotin plays a critical role in the differentiation of epidermal tissue, in the fatty acid and glucose metabolism. Qualitative and quantitative changes in the synthesis of keratin filaments, interruption of the co-ordination from keratinisation until cornification and intercellular cementing substance of poor quality occur in the hoof horn of biotin deficient calves (Mulling et al., 1999). The addition of supplementary biotin in diets has been found to significantly increase hoof hardness and reduce lameness of cows (Schmid, 1995; Fitzgerald et al., 2000). The aim of this experiment was to compare changes in locomotion score and lesion score with the results of mechanical testing of the sole and white line horn in cows supplemented and not supplemented with biotin.