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Adhesion of K88ac-positive E. coli to porcine brush borders in the presence of various feed additives

Published online by Cambridge University Press:  05 November 2021

P.H. Jones ,
B.G. Miller  and
J. Gibson
P.H. Jones
Affiliation:
University of Bristol, Division of Animal Health and Husbandry, Department of Clinical Veterinary Science, Langford House, Langford, Bristol BS18 7DU, Great Britain
B.G. Miller
Affiliation:
University of Bristol, Division of Animal Health and Husbandry, Department of Clinical Veterinary Science, Langford House, Langford, Bristol BS18 7DU, Great Britain
J. Gibson
Affiliation:
Parnutt Foods Limited, Hadley Road, Woodbridge Industrial Estate, Sleaford, Lincolnshire NG34 7EG, Great Britain
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Extract

Post-weaning diarrhoea (PWD) is a common problem in the pig industry. Following weaning, severe diarrhoea may occur due to colonisation of the small intestine by opportunistic pathogens, predominantly E. coli. Many serotypes of E. coli are associated with the disease but organisms with the K88 fimbrial antigen predominate. The K88 antigen enables E. coli to adhere to the mucosal surface of the small intestine thereby facilitating colonisation. Many feed additives are available which reputedly inhibit this binding. The aim of this project was to assess whether a selection of these feed additives could inhibit binding in an in vitro model.

Type
Programme
Information
Proceedings of the British Society of Animal Science , Volume 1997 , 1997 , pp. 63
Copyright
Copyright © British Society of Animal Science 1997

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References

de Leeuw, and Guinée, (Editors) ‘Current Topics In Veterinary Medicine And Animal Science. Volume 13. Laboratory Diagnosis In Neonatal Calf And Pig Diarrhoea’. Published by Martinus Nijhoff Publishers (1981). Pages 171–174.Google Scholar