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Absence of plasma leptin or metabolite variation after subcutaneous melatonin release in adult ewe
Published online by Cambridge University Press: 20 November 2017
Extract
Leptin is mainly secreted by adipose tissue and plays an important role in body homeostasis and in a great number of physiological functions, particularly in reproduction. Sheep is a seasonal ruminant whose reproductive period is initiated during decreasing day lengths. Leptin expression and secretion have shown to be decreased during short days, independently of adipose cell size, feed intake and ovarian activity (Bocquier et al., 1998). The mechanism by which leptin could be modulated is not well understood (Chilliard and Bocquier, 2000). As nocturnal pineal melatonin secretion is increased during short days, it appears as a potential mediator in the regulation of plasma leptin by photoperiod. The aim of this study was to test this hypothesis by comparing plasma leptin and metabolite concentrations in adult ewes exposed to long days treated (M), or not (LD), with melatonin after 20 and 69 days.
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- Copyright © The British Society of Animal Science 2002